8QZN

DARPin-Armadillo fusion protein with a selected Tyrosin pocket binding to the fused target peptide

Summary for 8QZN

Entry DOI	10.2210/pdb8qzn/pdb
Descriptor	DARPin-Armadillo fusion protein with Tyrosin pocket and linked target peptide, 1,2-ETHANEDIOL, SULFATE ION, ... (4 entities in total)
Functional Keywords	designed armadillo repeat proteins, yeast surface display, modular binder technology, specificity selection, ngs, de novo protein
Biological source	synthetic construct
Total number of polymer chains	1
Total formula weight	38463.61
Authors	Stark, Y.,Menard, F.,Jeliazkov, J.,Ernst, P.,Chembath, A.,Ashraf, M.,Hine, A.,Plueckthun, A. (deposition date: 2023-10-27, release date: 2024-07-03)
Primary citation	Stark, Y.,Menard, F.,Jeliazkov, J.R.,Ernst, P.,Chembath, A.,Ashraf, M.,Hine, A.V.,Pluckthun, A. Modular binder technology by NGS-aided, high-resolution selection in yeast of designed armadillo modules. Proc.Natl.Acad.Sci.USA, 121:e2318198121-e2318198121, 2024 Cited by PubMed: 38917007 DOI: 10.1073/pnas.2318198121 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation