6S7O
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![BU of 6s7o by Molmil](/molmil-images/mine/6s7o) | Cryo-EM structure of human oligosaccharyltransferase complex OST-A | 分子名称: | (2~{S},3~{R},4~{R},5~{S},6~{S})-2-(hydroxymethyl)-6-[(1~{S},2~{R},3~{R},4~{R},5'~{S},6~{S},7~{R},8~{S},9~{R},12~{R},13~{R},15~{S},16~{S},18~{R})-5',7,9,13-tetramethyl-3,15-bis(oxidanyl)spiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosane-6,2'-oxane]-16-yl]oxy-oxane-3,4,5-triol, (4R,7R)-4-hydroxy-N,N,N-trimethyl-4,9-dioxo-7-[(undecanoyloxy)methyl]-3,5,8-trioxa-4lambda~5~-phosphadocosan-1-aminium, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, ... | 著者 | Ramirez, A.S, Kowal, J, Locher, K.P. | 登録日 | 2019-07-05 | 公開日 | 2019-12-18 | 最終更新日 | 2020-07-29 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B. Science, 366, 2019
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4WVH
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![BU of 4wvh by Molmil](/molmil-images/mine/4wvh) | Crystal structure of the Type-I signal peptidase from Staphylococcus aureus (SpsB) in complex with a substrate peptide (pep1). | 分子名称: | Maltose-binding periplasmic protein,Signal peptidase IB, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, substrate peptide (pep1) | 著者 | Young, P.G, Ting, Y.T, Baker, E.N. | 登録日 | 2014-11-05 | 公開日 | 2015-09-23 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Peptide binding to a bacterial signal peptidase visualized by peptide tethering and carrier-driven crystallization. IUCrJ, 3, 2016
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1C04
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![BU of 1c04 by Molmil](/molmil-images/mine/1c04) | IDENTIFICATION OF KNOWN PROTEIN AND RNA STRUCTURES IN A 5 A MAP OF THE LARGE RIBOSOMAL SUBUNIT FROM HALOARCULA MARISMORTUI | 分子名称: | 23S RRNA FRAGMENT, RIBOSOMAL PROTEIN L11, RIBOSOMAL PROTEIN L14, ... | 著者 | Ban, N, Nissen, P, Capel, M, Moore, P.B, Steitz, T.A. | 登録日 | 1999-07-14 | 公開日 | 1999-08-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (5 Å) | 主引用文献 | Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit. Nature, 400, 1999
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8HFD
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![BU of 8hfd by Molmil](/molmil-images/mine/8hfd) | Crystal structure of allantoinase from E. coli BL21 | 分子名称: | Allantoinase, DI(HYDROXYETHYL)ETHER, ZINC ION | 著者 | Lin, E.S, Huang, H.Y, Yang, P.C, Liu, H.W, Huang, C.Y. | 登録日 | 2022-11-10 | 公開日 | 2023-10-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | 主引用文献 | Crystal Structure of Allantoinase from Escherichia coli BL21: A Molecular Insight into a Role of the Active Site Loops in Catalysis. Molecules, 28, 2023
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5M3O
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7Q63
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![BU of 7q63 by Molmil](/molmil-images/mine/7q63) | The tandem SH2 domains of SYK | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Bradshaw, W.J, Katis, V.L, Chen, Z, Bountra, C, von Delft, F, Gileadi, O, Brennan, P.E. | 登録日 | 2021-11-05 | 公開日 | 2021-11-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The tandem SH2 domains of SYK To Be Published
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8PFK
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![BU of 8pfk by Molmil](/molmil-images/mine/8pfk) | RNA structure with 1-methylpseudoridine, C2 space group | 分子名称: | MAGNESIUM ION, RNA (12-mer) | 著者 | Spingler, B, McAuley, K, Nievergelt, P, Thorn, A. | 登録日 | 2023-06-16 | 公開日 | 2024-01-31 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.321 Å) | 主引用文献 | RNA oligomers at atomic resolution containing 1-methylpseudouridine, an essential building block of mRNA vaccines. Chemmedchem, 19, 2024
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5LE6
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![BU of 5le6 by Molmil](/molmil-images/mine/5le6) | Crystal structure of DARPin-DARPin rigid fusion, variant DD_D12_09_D12 | 分子名称: | DD_D12_09_D12, GLYCEROL, SULFATE ION | 著者 | Batyuk, A, Wu, Y, Mittl, P.R, Plueckthun, A. | 登録日 | 2016-06-29 | 公開日 | 2017-08-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Rigidly connected multispecific artificial binders with adjustable geometries. Sci Rep, 7, 2017
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6LYV
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5LJY
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![BU of 5ljy by Molmil](/molmil-images/mine/5ljy) | Structure of hantavirus envelope glycoprotein Gc in complex with scFv A5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, COBALT HEXAMMINE(III), Envelopment polyprotein, ... | 著者 | Guardado-Calvo, P, Stettner, E, Jeffers, S.A, Rey, F.A. | 登録日 | 2016-07-20 | 公開日 | 2016-09-14 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Mechanistic Insight into Bunyavirus-Induced Membrane Fusion from Structure-Function Analyses of the Hantavirus Envelope Glycoprotein Gc. Plos Pathog., 12, 2016
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7UFV
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![BU of 7ufv by Molmil](/molmil-images/mine/7ufv) | Crystal structure of the WDR domain of human DCAF1 in complex with OICR-6766 | 分子名称: | (3P)-N-[(1S)-3-amino-1-(3-chlorophenyl)-3-oxopropyl]-3-(2-fluorophenyl)-1H-pyrazole-4-carboxamide, DDB1- and CUL4-associated factor 1, UNKNOWN ATOM OR ION | 著者 | Kimani, S, Li, A, Li, Y, Dong, A, Hutchinson, A, Seitova, A, Wilson, B, Al-Awar, R, Vedadi, M, Brown, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC) | 登録日 | 2022-03-23 | 公開日 | 2022-05-04 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Discovery of Nanomolar DCAF1 Small Molecule Ligands. J.Med.Chem., 66, 2023
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6GRJ
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![BU of 6grj by Molmil](/molmil-images/mine/6grj) | Structure of the AhlB pore of the tripartite alpha-pore forming toxin, AHL, from Aeromonas hydrophila. | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, AhlB, CHLORIDE ION, ... | 著者 | Churchill-Angus, A.M, Wilson, J.S, Baker, P.J. | 登録日 | 2018-06-11 | 公開日 | 2019-07-03 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Identification and structural analysis of the tripartite alpha-pore forming toxin of Aeromonas hydrophila. Nat Commun, 10, 2019
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6SA7
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![BU of 6sa7 by Molmil](/molmil-images/mine/6sa7) | DARPin-Armadillo fusion C8long83 | 分子名称: | DARPin-Armadillo fusion C8long83 | 著者 | Ernst, P, Honegger, A, van der Valk, F, Ewald, C, Mittl, P.R.E, Plucktun, A. | 登録日 | 2019-07-16 | 公開日 | 2019-11-20 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts. Sci Rep, 9, 2019
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5I9J
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![BU of 5i9j by Molmil](/molmil-images/mine/5i9j) | Structure of the cholesterol and lutein-binding domain of human STARD3 at 1.74A | 分子名称: | 1,2-ETHANEDIOL, L(+)-TARTARIC ACID, SULFATE ION, ... | 著者 | Horvath, M.P, Bernstein, P.S, Li, B, George, E.W, Tran, Q.T. | 登録日 | 2016-02-20 | 公開日 | 2016-03-16 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Structure of the lutein-binding domain of human StARD3 at 1.74 angstrom resolution and model of a complex with lutein. Acta Crystallogr.,Sect.F, 72, 2016
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5AJZ
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![BU of 5ajz by Molmil](/molmil-images/mine/5ajz) | Human PFKFB3 in complex with an indole inhibitor 5 | 分子名称: | 2-azanyl-N-[4-[(3-cyano-1H-indol-5-yl)oxy]phenyl]ethanamide, 6-O-phosphono-beta-D-fructofuranose, 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 3, ... | 著者 | Boyd, S, Brookfield, J.L, Critchlow, S.E, Cumming, I.A, Curtis, N.J, Debreczeni, J.E, Degorce, S.L, Donald, C, Evans, N.J, Groombridge, S, Hopcroft, P, Jones, N.P, Kettle, J.G, Lamont, S, Lewis, H.J, MacFaull, P, McLoughlin, S.B, Rigoreau, L.J.M, Smith, J.M, St-Gallay, S, Stock, J.K, Wheatley, E.R, Winter, J, Wingfield, J. | 登録日 | 2015-02-27 | 公開日 | 2015-04-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase Pfkfb3. J.Med.Chem., 58, 2015
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6LSG
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![BU of 6lsg by Molmil](/molmil-images/mine/6lsg) | Crystal structure of the enterovirus 71 polymerase elongation complex (C0S6M form) | 分子名称: | Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ... | 著者 | Li, R, Wang, M, Jing, X, Gong, P. | 登録日 | 2020-01-17 | 公開日 | 2020-04-29 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures. Nat Commun, 11, 2020
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6GYL
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![BU of 6gyl by Molmil](/molmil-images/mine/6gyl) | Structure of a yeast closed complex with distorted DNA (core CCdist) | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB2, ... | 著者 | Dienemann, C, Schwalb, B, Schilbach, S, Cramer, P. | 登録日 | 2018-06-30 | 公開日 | 2018-12-05 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Promoter Distortion and Opening in the RNA Polymerase II Cleft. Mol. Cell, 73, 2019
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7NH4
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8P5Q
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7NH5
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6ETJ
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![BU of 6etj by Molmil](/molmil-images/mine/6etj) | HUMAN PFKFB3 IN COMPLEX WITH KAN0438241 | 分子名称: | 4-[[3-(5-fluoranyl-2-oxidanyl-phenyl)phenyl]sulfonylamino]-2-oxidanyl-benzoic acid, 6-O-phosphono-beta-D-fructofuranose, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3, ... | 著者 | Gustafsson, N.M.S, Lundback, T, Farnegardh, K, Groth, P, Wiitta, E, Jonsson, M, Hallberg, K, Pennisi, R, Huguet Ninou, A, Martinsson, J, Norstrom, C, Schultz, J, Andersson, M, Markova, N, Marttila, P, Norin, M, Olin, T, Helleday, T. | 登録日 | 2017-10-26 | 公開日 | 2018-11-07 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun, 9, 2018
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7Q5P
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![BU of 7q5p by Molmil](/molmil-images/mine/7q5p) | Structure of VgrG1 from Pseudomonas protegens. | 分子名称: | Type VI secretion protein VgrG | 著者 | Guenther, P, Quentin, D, Ahmad, S, Sachar, K, Gatsogiannis, C, Whitney, J.C, Raunser, S. | 登録日 | 2021-11-04 | 公開日 | 2021-12-15 | 最終更新日 | 2022-02-02 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of a bacterial Rhs effector exported by the type VI secretion system. Plos Pathog., 18, 2022
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5IKH
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![BU of 5ikh by Molmil](/molmil-images/mine/5ikh) | Tobacco 5-epi-aristolochene synthase M4 mutant with (-)-premnaspirodiene | 分子名称: | (2R,5S,10R)-6,10-dimethyl-2-(prop-1-en-2-yl)spiro[4.5]dec-6-ene, 5-epi-aristolochene synthase, MAGNESIUM ION | 著者 | Koo, H.J, O'Maille, P.E, Louie, G.V, Bowman, M, Noel, J.P. | 登録日 | 2016-03-03 | 公開日 | 2016-10-05 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants. J.Antibiot., 69, 2016
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5FJX
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6EZZ
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![BU of 6ezz by Molmil](/molmil-images/mine/6ezz) | Crystal structure of Escherichia coli amine oxidase mutant E573Q | 分子名称: | CALCIUM ION, COPPER (II) ION, GLYCEROL, ... | 著者 | Gaule, T.G, Smith, M.A, Tych, K.M, Pirrat, P, Trinh, C.H, Pearson, A.R, Knowles, P.F, McPherson, M.J. | 登録日 | 2017-11-16 | 公開日 | 2018-08-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Oxygen Activation Switch in the Copper Amine Oxidase of Escherichia coli. Biochemistry, 57, 2018
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