Tobacco 5-epi-aristolochene synthase M4 mutant with (-)-premnaspirodiene

Summary for 5IKH

Related5IK0 5IK6 5IK9 5IKA 5IL3 5IL8 5ILD 5ILH 5ILI 5ILJ 5ILK 5ILY 5ILZ 5IM1
Descriptor5-epi-aristolochene synthase, (2R,5S,10R)-6,10-dimethyl-2-(prop-1-en-2-yl)spiro[4.5]dec-6-ene, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsterpene synthase, teas, teas-m4, premnaspirodiene, lyase
Biological sourceNicotiana tabacum (Common tobacco)
Cellular locationCytoplasm Q40577
Total number of polymer chains1
Total molecular weight63462.72
Koo, H.J.,O'Maille, P.E.,Louie, G.V.,Bowman, M.,Noel, J.P. (deposition date: 2016-03-03, release date: 2016-10-05)
Primary citation
Koo, H.J.,Vickery, C.R.,Xu, Y.,Louie, G.V.,O'Maille, P.E.,Bowman, M.,Nartey, C.M.,Burkart, M.D.,Noel, J.P.
Biosynthetic potential of sesquiterpene synthases: product profiles of Egyptian Henbane premnaspirodiene synthase and related mutants.
J.Antibiot., 69:524-533, 2016
PubMed: 27328867 (PDB entries with the same primary citation)
DOI: 10.1038/ja.2016.68
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22750.9%2.5%6.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-08-05