4XDO
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6XRT
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5J0E
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![BU of 5j0e by Molmil](/molmil-images/mine/5j0e) | Crystal structures of Pribnow box consensus promoter sequence (P32) | 分子名称: | Complementary sequence, Pribnow box consensus promoter sequence, ZINC ION | 著者 | Mandal, P.K, Collie, G.W, Kauffmann, B, Huc, I. | 登録日 | 2016-03-28 | 公開日 | 2016-05-18 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structure elucidation of the Pribnow box consensus promoter sequence by racemic DNA crystallography. Nucleic Acids Res., 44, 2016
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6V6Z
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![BU of 6v6z by Molmil](/molmil-images/mine/6v6z) | Crystal structure of N-[(4-methoxyphenyl)sulfonyl]-N-(4-{[(4-methoxyphenyl)sulfonyl]amino}naphthalen-1-yl)glycine bound to human Keap1 Kelch domain | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, DITHIANE DIOL, FORMIC ACID, ... | 著者 | Lazzara, P.R, David, B.P, Ankireddy, A, Richardson, B.G, Dye, K, Ratia, K.M, Reddy, S.P, Moore, T.W. | 登録日 | 2019-12-06 | 公開日 | 2020-04-29 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Synthesis and Evaluation of Noncovalent Naphthalene-Based KEAP1-NRF2 Inhibitors. Acs Med.Chem.Lett., 11, 2020
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5MFN
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![BU of 5mfn by Molmil](/molmil-images/mine/5mfn) | Designed armadillo repeat protein YIIIM5AII | 分子名称: | CALCIUM ION, D-MALATE, YIIIM5AII | 著者 | Hansen, S, Ernst, P, Reichen, C, Ewald, C, Mittl, P, Plueckthun, A. | 登録日 | 2016-11-18 | 公開日 | 2017-09-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Curvature of designed armadillo repeat proteins allows modular peptide binding. J. Struct. Biol., 201, 2018
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4XBB
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![BU of 4xbb by Molmil](/molmil-images/mine/4xbb) | 1.85A resolution structure of Norovirus 3CL protease complex with a covalently bound dipeptidyl inhibitor diethyl [(1R,2S)-2-[(N-{[(3-chlorobenzyl)oxy]carbonyl}-3-cyclohexyl-L-alanyl)amino]-1-hydroxy-3-(2-oxo-2H-pyrrol-3-yl)propyl]phosphonate | 分子名称: | 3C-LIKE PROTEASE, SULFATE ION, diethyl [(1R,2S)-2-[(N-{[(3-chlorobenzyl)oxy]carbonyl}-3-cyclohexyl-L-alanyl)amino]-1-hydroxy-3-(2-oxo-2H-pyrrol-3-yl)propyl]phosphonate | 著者 | Lovell, S, Battaile, K.P, Mehzabeen, N, Kankanamalage, A.C.G, Kim, Y, Weerawarna, P.M, Uy, R.A.Z, Damalanka, V.C, Mandadapu, S.R, Alliston, K.R, Groutas, W.C, Chang, K.-O. | 登録日 | 2014-12-16 | 公開日 | 2015-03-25 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structure-Guided Design and Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease. Structure-Activity Relationships and Biochemical, X-ray Crystallographic, Cell-Based, and In Vivo Studies. J.Med.Chem., 58, 2015
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4XBI
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![BU of 4xbi by Molmil](/molmil-images/mine/4xbi) | Structure Of A Malarial Protein Involved in Proteostasis | 分子名称: | ClpB protein, putative,Green fluorescent protein, SULFATE ION | 著者 | Egea, P.F, Ah Young, A.P, Cascio, D. | 登録日 | 2014-12-17 | 公開日 | 2015-07-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.013 Å) | 主引用文献 | Structural mapping of the ClpB ATPases of Plasmodium falciparum: Targeting protein folding and secretion for antimalarial drug design. Protein Sci., 24, 2015
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7JQL
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![BU of 7jql by Molmil](/molmil-images/mine/7jql) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with Bac7-001, mRNA, and deacylated P-site tRNA at 3.00A resolution | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Mardirossian, M, Sola, R, Beckert, B, Valencic, E, Collis, D.W.P, Borisek, J, Armas, F, Di Stasi, A, Buchmann, J, Syroegin, E.A, Polikanov, Y.S, Magistrato, A, Hilpert, K, Wilson, D.N, Scocchi, M. | 登録日 | 2020-08-11 | 公開日 | 2020-08-26 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Peptide Inhibitors of Bacterial Protein Synthesis with Broad Spectrum and SbmA-Independent Bactericidal Activity against Clinical Pathogens. J.Med.Chem., 63, 2020
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3IVN
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![BU of 3ivn by Molmil](/molmil-images/mine/3ivn) | Structure of the U65C mutant A-riboswitch aptamer from the Bacillus subtilis pbuE operon | 分子名称: | A-riboswitch, BROMIDE ION, MAGNESIUM ION | 著者 | Delfosse, V, Dagenais, P, Chausse, D, Di Tomasso, G, Legault, P. | 登録日 | 2009-09-01 | 公開日 | 2010-01-19 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Riboswitch structure: an internal residue mimicking the purine ligand. Nucleic Acids Res., 38, 2010
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6XU5
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![BU of 6xu5 by Molmil](/molmil-images/mine/6xu5) | Human myelin protein P2 mutant N2D | 分子名称: | CITRIC ACID, Myelin P2 protein, PALMITIC ACID | 著者 | Ruskamo, S, Lehtimaki, M, Kursula, P. | 登録日 | 2020-01-17 | 公開日 | 2020-04-08 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Cryo-EM, X-ray diffraction, and atomistic simulations reveal determinants for the formation of a supramolecular myelin-like proteolipid lattice. J.Biol.Chem., 295, 2020
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4XHE
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![BU of 4xhe by Molmil](/molmil-images/mine/4xhe) | Crystal Structure of A-AChBP in complex with pinnatoxin A | 分子名称: | CALCIUM ION, CHLORIDE ION, Pinnatoxin A, ... | 著者 | Bourne, Y, Sulzenbacher, G, Marchot, P. | 登録日 | 2015-01-05 | 公開日 | 2015-06-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal alpha 7 from Muscle alpha 12 beta gamma delta nAChRs. Structure, 23, 2015
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6T17
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6Y4L
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6PPG
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6FBU
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![BU of 6fbu by Molmil](/molmil-images/mine/6fbu) | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (E2Q) in complex with AP-site containing DNA substrate | 分子名称: | ACETATE ION, DNA (5'-D(P*CP*CP*AP*GP*GP*AP*(PED)P*GP*AP*AP*GP*CP*C)-3'), DNA (5'-D(P*GP*GP*CP*TP*TP*CP*AP*TP*CP*CP*TP*G)-3'), ... | 著者 | Pomyalov, S, Lansky, S, Golan, G, Zharkov, D.O, Grollman, A.P, Shoham, G. | 登録日 | 2017-12-19 | 公開日 | 2019-01-30 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of the DNA repair enzyme endonuclease-VIII (Nei) from E. coli (E2Q) in complex with AP-site containing DNA substrate To Be Published
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7O1Q
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![BU of 7o1q by Molmil](/molmil-images/mine/7o1q) | Amyloid beta oligomer displayed on the alpha hemolysin scaffold | 分子名称: | Alpha-hemolysin hybridized Abeta | 著者 | Wu, J, Blum, T.B, Farrell, D.P, DiMaio, F, Abrahams, J.P, Luo, J. | 登録日 | 2021-03-30 | 公開日 | 2021-04-14 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-electron Microscopy Imaging of Alzheimer's Amyloid-beta 42 Oligomer Displayed on a Functionally and Structurally Relevant Scaffold. Angew.Chem.Int.Ed.Engl., 60, 2021
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7NRI
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![BU of 7nri by Molmil](/molmil-images/mine/7nri) | Structure of the darobactin-bound E. coli BAM complex (BamABCDE) | 分子名称: | 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, Outer membrane protein assembly factor BamA, Outer membrane protein assembly factor BamB, ... | 著者 | Jakob, R.P, Kaur, H, Marzinek, J.K, Green, R, Imai, Y, Bolla, J, Robinson, C, Bond, P.J, Lewis, K, Maier, T, Hiller, S. | 登録日 | 2021-03-03 | 公開日 | 2021-04-21 | 最終更新日 | 2021-05-19 | 実験手法 | ELECTRON MICROSCOPY (3.03 Å) | 主引用文献 | The antibiotic darobactin mimics a beta-strand to inhibit outer membrane insertase. Nature, 593, 2021
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6YDK
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![BU of 6ydk by Molmil](/molmil-images/mine/6ydk) | Substrate-free P146A variant of beta-phosphoglucomutase from Lactococcus lactis | 分子名称: | Beta-phosphoglucomutase, MAGNESIUM ION | 著者 | Wood, H.P, Cruz-Navarrete, F.A, Baxter, N.J, Trevitt, C.R, Robertson, A.J, Dix, S.R, Hounslow, A.M, Cliff, M.J, Waltho, J.P. | 登録日 | 2020-03-20 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Allomorphy as a mechanism of post-translational control of enzyme activity. Nat Commun, 11, 2020
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5FMA
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![BU of 5fma by Molmil](/molmil-images/mine/5fma) | human Notch 1, EGF 4-7 | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ... | 著者 | Weisshuhn, P.C, Sheppard, D, Taylor, P, Whiteman, P, Lea, S.M, Handford, P.A, Redfield, C. | 登録日 | 2015-11-02 | 公開日 | 2016-04-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Non-Linear and Flexible Regions of the Human Notch1 Extracellular Domain Revealed by High-Resolution Structural Studies. Structure, 24, 2016
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5JAU
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6VMB
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![BU of 6vmb by Molmil](/molmil-images/mine/6vmb) | Chloroplast ATP synthase (C1, CF1FO) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase delta chain, ... | 著者 | Yang, J.-H, Williams, D, Kandiah, E, Fromme, P, Chiu, P.-L. | 登録日 | 2020-01-27 | 公開日 | 2020-09-09 | 最終更新日 | 2020-09-16 | 実験手法 | ELECTRON MICROSCOPY (5.23 Å) | 主引用文献 | Structural basis of redox modulation on chloroplast ATP synthase. Commun Biol, 3, 2020
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6GTF
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![BU of 6gtf by Molmil](/molmil-images/mine/6gtf) | Transient state structure of CRISPR-Cpf1 (Cas12a) I5 conformation | 分子名称: | CRISPR-associated endonuclease Cas12a, DNA (5'-D(P*AP*TP*GP*AP*CP*TP*TP*CP*TP*CP*TP*AP*AP*CP*AP*AP*GP*CP*TP*CP*G)-3'), DNA (5'-D(P*CP*GP*AP*GP*CP*TP*CP*GP*TP*TP*AP*GP*AP*GP*AP*A)-3'), ... | 著者 | Montoya, G, Mesa, P, Stella, S. | 登録日 | 2018-06-18 | 公開日 | 2018-12-19 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | 主引用文献 | Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity. Cell, 175, 2018
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7OH4
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![BU of 7oh4 by Molmil](/molmil-images/mine/7oh4) | Cryo-EM structure of Drs2p-Cdc50p in the E1 state with PI4P and Mg2+ bound | 分子名称: | (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Timcenko, M, Dieudonne, T, Montigny, C, Boesen, T, Lyons, J.A, Lenoir, G, Nissen, P. | 登録日 | 2021-05-09 | 公開日 | 2021-06-09 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis of substrate-independent phosphorylation in a P4-ATPase lipid flippase J.Mol.Biol., 2021
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7OH7
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![BU of 7oh7 by Molmil](/molmil-images/mine/7oh7) | Cryo-EM structure of Drs2p-Cdc50p in the E1-AMPPCP state with PI4P bound | 分子名称: | (2R)-1-{[(R)-hydroxy{[(1R,2R,3R,4R,5S,6R)-2,3,5,6-tetrahydroxy-4-(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy)propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cell division control protein 50, ... | 著者 | Timcenko, M, Dieudonne, T, Montigny, C, Boesen, T, Lyons, J.A, Lenoir, G, Nissen, P. | 登録日 | 2021-05-09 | 公開日 | 2021-06-09 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structural basis of substrate-independent phosphorylation in a P4-ATPase lipid flippase J.Mol.Biol., 2021
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6VI0
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