7OH4

Cryo-EM structure of Drs2p-Cdc50p in the E1 state with PI4P and Mg2+ bound

Summary for 7OH4

Entry DOI	10.2210/pdb7oh4/pdb
EMDB information	12893 12894 12895 12896
Descriptor	Probable phospholipid-transporting ATPase DRS2,Probable phospholipid-transporting ATPase DRS2, Cell division control protein 50, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywords	lipid flippase, p4 atpase, trans-golgi network, phosphatidylserine transport, membrane protein
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More
Total number of polymer chains	2
Total formula weight	214357.26
Authors	Timcenko, M.,Dieudonne, T.,Montigny, C.,Boesen, T.,Lyons, J.A.,Lenoir, G.,Nissen, P. (deposition date: 2021-05-09, release date: 2021-06-09)
Primary citation	Timcenko, M.,Dieudonne, T.,Montigny, C.,Boesen, T.,Lyons, J.A.,Lenoir, G.,Nissen, P. Structural basis of substrate-independent phosphorylation in a P4-ATPase lipid flippase J.Mol.Biol., :167062-, 2021 Cited by PubMed: 34023399 DOI: 10.1016/j.jmb.2021.167062 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation