2J8J
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![BU of 2j8j by Molmil](/molmil-images/mine/2j8j) | Solution Structure of the A4 Domain of Blood Coagulation Factor XI | 分子名称: | COAGULATION FACTOR XI | 著者 | Samuel, D, Cheng, H, Riley, P.W, Canutescu, A.A, Bu, Z, Walsh, P.N, Roder, H. | 登録日 | 2006-10-25 | 公開日 | 2007-10-02 | 最終更新日 | 2011-07-13 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the A4 Domain of Factor Xi Sheds Light on the Mechanism of Zymogen Activation. Proc.Natl.Acad.Sci.USA, 104, 2007
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4E36
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![BU of 4e36 by Molmil](/molmil-images/mine/4e36) | Crystal structure of the human Endoplasmic Reticulum Aminopeptidase 2 variant N392K | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Birtley, J.R, Saridakis, E, Pegias, P, Stratikos, E, Mavridis, I.M. | 登録日 | 2012-03-09 | 公開日 | 2012-08-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | A common single nucleotide polymorphism in endoplasmic reticulum aminopeptidase 2 induces a specificity switch that leads to altered antigen processing. J.Immunol., 189, 2012
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4Q6X
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![BU of 4q6x by Molmil](/molmil-images/mine/4q6x) | Structure of phospholipase D Beta1B1i from Sicarius terrosus venom at 2.14 A resolution | 分子名称: | MAGNESIUM ION, Phospholipase D StSicTox-betaIC1 | 著者 | Lajoie, D.M, Roberts, S.A, Zobel-Thropp, P.A, Binford, G.J, Cordes, M.H. | 登録日 | 2014-04-23 | 公開日 | 2015-03-18 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | 主引用文献 | Variable Substrate Preference among Phospholipase D Toxins from Sicariid Spiders. J.Biol.Chem., 290, 2015
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1XI6
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![BU of 1xi6 by Molmil](/molmil-images/mine/1xi6) | Extragenic suppressor from Pyrococcus furiosus Pfu-1862794-001 | 分子名称: | extragenic suppressor | 著者 | Zhao, M, Chang, J.C, Zhou, W, Chen, L, Horanyi, P, Xu, H, Yang, H, Liu, Z.-J, Habel, J.E, Lee, D, Chang, S.-H, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2004-09-21 | 公開日 | 2004-11-30 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Extragenic suppressor from Pyrococcus furiosus Pfu-1862794-001 To be published
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2ZZ8
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![BU of 2zz8 by Molmil](/molmil-images/mine/2zz8) | |
1S0P
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![BU of 1s0p by Molmil](/molmil-images/mine/1s0p) | Structure of the N-Terminal Domain of the Adenylyl Cyclase-Associated Protein (CAP) from Dictyostelium discoideum. | 分子名称: | Adenylyl cyclase-associated protein, MAGNESIUM ION | 著者 | Ksiazek, D, Brandstetter, H, Israel, L, Bourenkov, G.P, Katchalova, G, Janssen, K.P, Bartunik, H.D, Noegel, A.A, Schleicher, M, Holak, T.A. | 登録日 | 2004-01-01 | 公開日 | 2004-01-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | STRUCTURE OF THE N-TERMINAL DOMAIN OF THE ADENYLYL
CYCLASE-ASSOCIATED PROTEIN (CAP) FROM DICTYOSTELIUM DISCOIDEUM Structure, 11, 2003
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5I67
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![BU of 5i67 by Molmil](/molmil-images/mine/5i67) | Crystal Structure Analysis of MTB PEPCK mutant C273S | 分子名称: | DI(HYDROXYETHYL)ETHER, GUANOSINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ... | 著者 | Dostal, J, Pachl, P, Machova, I, Pichova, I, Snasel, J. | 登録日 | 2016-02-16 | 公開日 | 2016-04-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.602 Å) | 主引用文献 | Crystal Structure Analysis of MTB PEPCK mutant C273S To Be Published
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1XJK
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![BU of 1xjk by Molmil](/molmil-images/mine/1xjk) | Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dGTP-ADP complex | 分子名称: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Larsson, K.-M, Jordan, A, Eliasson, R, Reichard, P, Logan, D.T, Nordlund, P. | 登録日 | 2004-09-23 | 公開日 | 2005-11-22 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | 主引用文献 | Structural mechanism of allosteric substrate specificity regulation in a ribonucleotide reductase. Nat.Struct.Mol.Biol., 11, 2004
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3IF4
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![BU of 3if4 by Molmil](/molmil-images/mine/3if4) | Structure from the mobile metagenome of North West Arm Sewage Outfall: Integron Cassette Protein Hfx_Cass5 | 分子名称: | Integron Cassette Protein Hfx_Cass5 | 著者 | Sureshan, V, Deshpande, C.N, Harrop, S.J, Evdokimova, E, Kudrytska, M, Koenig, J.E, Osipiuk, J, Edwards, A, Savchenko, A, Joachimiak, A, Doolittle, W.F, Stokes, H.W, Curmi, P.M.G, Mabbutt, B.C, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2009-07-24 | 公開日 | 2009-09-08 | 最終更新日 | 2013-02-06 | 実験手法 | X-RAY DIFFRACTION (2.181 Å) | 主引用文献 | Integron gene cassettes: a repository of novel protein folds with distinct interaction sites. Plos One, 8, 2013
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5I7E
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7KI0
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![BU of 7ki0 by Molmil](/molmil-images/mine/7ki0) | Semaglutide-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in Complex with Gs protein | 分子名称: | 17-amino-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan-1-oic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | 著者 | Zhang, X, Belousoff, M.J, Danev, R, Sexton, P.M, Wootten, D. | 登録日 | 2020-10-22 | 公開日 | 2021-08-04 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes. Cell Rep, 36, 2021
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7WSJ
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![BU of 7wsj by Molmil](/molmil-images/mine/7wsj) | Crystal structure of the tandem B-box domain of Arabidopsis thaliana CONSTANS | 分子名称: | ZINC ION, Zinc finger protein CONSTANS | 著者 | Dahal, P, Pathak, D, Kwon, E, Kim, D.Y. | 登録日 | 2022-01-29 | 公開日 | 2022-03-02 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of a tandem B-box domain from Arabidopsis CONSTANS. Biochem.Biophys.Res.Commun., 599, 2022
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4LAU
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![BU of 4lau by Molmil](/molmil-images/mine/4lau) | Crystal structure of human AR complexed with NADP+ and {2-[(4-bromobenzyl)carbamoyl]-5-chlorophenoxy}acetic acid | 分子名称: | Aldose reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, {2-[(4-bromobenzyl)carbamoyl]-5-chlorophenoxy}acetic acid | 著者 | Cousido-Siah, A, Mitschler, A, Ruiz, F.X, Fanfrlik, J, Kolar, M, Hobza, P, Podjarny, A. | 登録日 | 2013-06-20 | 公開日 | 2014-04-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (0.843 Å) | 主引用文献 | Modulation of aldose reductase inhibition by halogen bond tuning. Acs Chem.Biol., 8, 2013
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7KI1
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![BU of 7ki1 by Molmil](/molmil-images/mine/7ki1) | Taspoglutide-bound Glucagon-Like Peptide-1 (GLP-1) Receptor in Complex with Gs Protein | 分子名称: | Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Zhang, X, Belousoff, M.J, Danev, R, Sexton, P.M, Wootten, D. | 登録日 | 2020-10-22 | 公開日 | 2021-08-04 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Structure and dynamics of semaglutide- and taspoglutide-bound GLP-1R-Gs complexes. Cell Rep, 36, 2021
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1P9U
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![BU of 1p9u by Molmil](/molmil-images/mine/1p9u) | Coronavirus Main Proteinase (3CLpro) Structure: Basis for Design of anti-SARS Drugs | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, PHQ-VNSTLQ-CHLOROMETHYLKETONE INHIBITOR, SULFATE ION, ... | 著者 | Anand, K, Ziebuhr, J, Wadhwani, P, Mesters, J.R, Hilgenfeld, R. | 登録日 | 2003-05-12 | 公開日 | 2003-05-20 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Coronavirus Main Proteinase (3CLpro) Structure: Basis for Design of anti-SARS Drugs Science, 300, 2003
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1DIP
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![BU of 1dip by Molmil](/molmil-images/mine/1dip) | THE SOLUTION STRUCTURE OF PORCINE DELTA-SLEEP-INDUCING PEPTIDE IMMUNOREACTIVE PEPTIDE, NMR, 10 STRUCTURES | 分子名称: | DELTA-SLEEP-INDUCING PEPTIDE IMMUNOREACTIVE PEPTIDE | 著者 | Roesch, P, Seidel, G, Adermann, K, Schindler, T, Ejchart, A, Jaenicke, R, Forssmann, W.G. | 登録日 | 1997-04-09 | 公開日 | 1997-10-15 | 最終更新日 | 2022-02-16 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of porcine delta sleep-inducing peptide immunoreactive peptide A homolog of the shortsighted gene product. J.Biol.Chem., 272, 1997
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1XOS
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![BU of 1xos by Molmil](/molmil-images/mine/1xos) | Catalytic Domain Of Human Phosphodiesterase 4B In Complex With Sildenafil | 分子名称: | 5-{2-ETHOXY-5-[(4-METHYLPIPERAZIN-1-YL)SULFONYL]PHENYL}-1-METHYL-3-PROPYL-1H,6H,7H-PYRAZOLO[4,3-D]PYRIMIDIN-7-ONE, MAGNESIUM ION, SULFATE ION, ... | 著者 | Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | 登録日 | 2004-10-06 | 公開日 | 2004-12-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases. STRUCTURE, 12, 2004
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2DQY
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![BU of 2dqy by Molmil](/molmil-images/mine/2dqy) | Crystal structure of human carboxylesterase in complex with cholate and palmitate | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLIC ACID, Liver carboxylesterase 1, ... | 著者 | Bencharit, S, Edwards, C.C, Morton, C.L, Howard-Williams, E.L, Potter, P.M, Redinbo, M.R. | 登録日 | 2006-06-02 | 公開日 | 2006-08-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Multisite promiscuity in the processing of endogenous substrates by human carboxylesterase 1 J.Mol.Biol., 363, 2006
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1XQM
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![BU of 1xqm by Molmil](/molmil-images/mine/1xqm) | Variations on the GFP chromophore scaffold: A fragmented 5-membered heterocycle revealed in the 2.1A crystal structure of a non-fluorescent chromoprotein | 分子名称: | ACETIC ACID, kindling fluorescent protein | 著者 | Wilmann, P.G, Petersen, J, Devenish, R.J, Prescott, M, Rossjohn, J. | 登録日 | 2004-10-13 | 公開日 | 2004-11-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Variations on the GFP chromophore: A polypeptide fragmentation within the chromophore revealed in the 2.1-A crystal structure of a nonfluorescent chromoprotein from Anemonia sulcata J.Biol.Chem., 280, 2005
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1XOZ
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![BU of 1xoz by Molmil](/molmil-images/mine/1xoz) | Catalytic Domain Of Human Phosphodiesterase 5A In Complex With Tadalafil | 分子名称: | 6-BENZO[1,3]DIOXOL-5-YL-2-METHYL-2,3,6,7,12,12A-HEXAHYDRO-PYRAZINO[1',2':1,6]PYRIDO[3,4-B]INDOLE-1,4-DIONE, MAGNESIUM ION, ZINC ION, ... | 著者 | Card, G.L, England, B.P, Suzuki, Y, Fong, D, Powell, B, Lee, B, Luu, C, Tabrizizad, M, Gillette, S, Ibrahim, P.N, Artis, D.R, Bollag, G, Milburn, M.V, Kim, S.-H, Schlessinger, J, Zhang, K.Y.J. | 登録日 | 2004-10-07 | 公開日 | 2004-12-14 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Structural Basis for the Activity of Drugs that Inhibit Phosphodiesterases. STRUCTURE, 12, 2004
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1XRF
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![BU of 1xrf by Molmil](/molmil-images/mine/1xrf) | The Crystal Structure of a Novel, Latent Dihydroorotase from Aquifex aeolicus at 1.7 A resolution | 分子名称: | Dihydroorotase, SULFATE ION, ZINC ION | 著者 | Martin, P.D, Purcarea, C, Zhang, P, Vaishnav, A, Sadecki, S, Guy-Evans, H.I, Evans, D.R, Edwards, B.F. | 登録日 | 2004-10-14 | 公開日 | 2005-07-05 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The crystal structure of a novel, latent dihydroorotase from Aquifex aeolicus at 1.7A resolution J.Mol.Biol., 348, 2005
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4LHO
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![BU of 4lho by Molmil](/molmil-images/mine/4lho) | Crystal Structure of FG41Malonate Semialdehyde Decarboxylase inhibited by 3-bromopropiolate | 分子名称: | 3-chloro-3-oxopropanoic acid, FG41 Malonate Semialdehyde Decarboxylase, PHOSPHATE ION | 著者 | Guo, Y, Serrano, H, Poelarends, G.J, Johnson Jr, W.H, Hackert, M.L, Whitman, C.P. | 登録日 | 2013-07-01 | 公開日 | 2013-07-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.224 Å) | 主引用文献 | Kinetic, Mutational, and Structural Analysis of Malonate Semialdehyde Decarboxylase from Coryneform Bacterium Strain FG41: Mechanistic Implications for the Decarboxylase and Hydratase Activities. Biochemistry, 52, 2013
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1JWT
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![BU of 1jwt by Molmil](/molmil-images/mine/1jwt) | CRYSTAL STRUCTURE OF THROMBIN IN COMPLEX WITH A NOVEL BICYCLIC LACTAM INHIBITOR | 分子名称: | 4-OXO-2-PHENYLMETHANESULFONYL-OCTAHYDRO-PYRROLO[1,2-A]PYRAZINE-6-CARBOXYLIC ACID [1-(N-HYDROXYCARBAMIMIDOYL)-PIPERIDIN-4-YLMETHYL]-AMIDE, Prothrombin | 著者 | Levesque, S, St-Denis, Y, Bachand, B, Preville, P, Leblond, L, Winocour, P.D, Edmunds, J.J, Rubin, J.R, Siddiqui, M.A. | 登録日 | 2001-09-05 | 公開日 | 2002-02-27 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Novel bicyclic lactam inhibitors of thrombin: potency and selectivity optimization through P1 residues. Bioorg.Med.Chem.Lett., 11, 2001
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2M27
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![BU of 2m27 by Molmil](/molmil-images/mine/2m27) | Major G-quadruplex structure formed in human VEGF promoter, a monomeric parallel-stranded quadruplex | 分子名称: | DNA_(5'-D(*CP*GP*GP*GP*GP*CP*GP*GP*GP*CP*CP*TP*TP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3')_ | 著者 | Agrawal, P, Hatzakis, E, Guo, K, Carver, M, Yang, D. | 登録日 | 2012-12-14 | 公開日 | 2013-09-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the major G-quadruplex formed in the human VEGF promoter in K+: insights into loop interactions of the parallel G-quadruplexes. Nucleic Acids Res., 41, 2013
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3I7L
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![BU of 3i7l by Molmil](/molmil-images/mine/3i7l) | Crystal Structure of DDB1 in Complex with the H-Box Motif of DDB2 | 分子名称: | DNA damage-binding protein 1, DNA damage-binding protein 2 | 著者 | Li, T, Robert, E.I, Breugel, P.C.V, Strubin, M, Zheng, N. | 登録日 | 2009-07-08 | 公開日 | 2009-12-08 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17, 2010
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