2M27
Major G-quadruplex structure formed in human VEGF promoter, a monomeric parallel-stranded quadruplex
Summary for 2M27
Entry DOI | 10.2210/pdb2m27/pdb |
Related | 1XAV 2F8U 2L7V 2LBY |
NMR Information | BMRB: 18902 |
Descriptor | DNA_(5'-D(*CP*GP*GP*GP*GP*CP*GP*GP*GP*CP*CP*TP*TP*GP*GP*GP*CP*GP*GP*GP*GP*T)-3')_ (1 entity in total) |
Functional Keywords | vegf promoter, g-quadruplex structure, anticancer drug target, parallel g-quadruplex, variable loop interactions, dna |
Biological source | Homo sapiens |
Total number of polymer chains | 1 |
Total formula weight | 6922.41 |
Authors | Agrawal, P.,Hatzakis, E.,Guo, K.,Carver, M.,Yang, D. (deposition date: 2012-12-14, release date: 2013-09-18, Last modification date: 2024-05-15) |
Primary citation | Agrawal, P.,Hatzakis, E.,Guo, K.,Carver, M.,Yang, D. Solution structure of the major G-quadruplex formed in the human VEGF promoter in K+: insights into loop interactions of the parallel G-quadruplexes. Nucleic Acids Res., 41:10584-10592, 2013 Cited by PubMed: 24005038DOI: 10.1093/nar/gkt784 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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