2K2J
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![BU of 2k2j by Molmil](/molmil-images/mine/2k2j) | NMR solution structure of the split PH domain from Phospholipase C gamma 2 | 分子名称: | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 | 著者 | Harris, R, Bunney, T.D, Katan, M, Driscoll, P.C. | 登録日 | 2008-04-02 | 公開日 | 2008-09-09 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Rac Regulates Its Effector Phospholipase C{gamma}2 through Interaction with a Split Pleckstrin Homology Domain. J.Biol.Chem., 283, 2008
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7D5F
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![BU of 7d5f by Molmil](/molmil-images/mine/7d5f) | Left-handed G-quadruplex containing 3 bulges | 分子名称: | 3xBulge-LHG4motif | 著者 | Winnerdy, F.R, Das, P, Ngo, K.H, Maity, A, Bakalar, B, Mechulam, Y, Schmitt, E, Phan, A.T. | 登録日 | 2020-09-25 | 公開日 | 2021-02-10 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Bulges in left-handed G-quadruplexes. Nucleic Acids Res., 49, 2021
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3UOX
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![BU of 3uox by Molmil](/molmil-images/mine/3uox) | Crystal Structure of OTEMO (FAD bound form 2) | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, OTEMO | 著者 | Shi, R, Matte, A, Cygler, M, Lau, P. | 登録日 | 2011-11-17 | 公開日 | 2012-02-01 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.956 Å) | 主引用文献 | Cloning, Baeyer-Villiger biooxidations, and structures of the camphor pathway 2-oxo-{Delta}(3)-4,5,5-trimethylcyclopentenylacetyl-coenzyme A monooxygenase of Pseudomonas putida ATCC 17453. Appl.Environ.Microbiol., 78, 2012
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1YWR
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![BU of 1ywr by Molmil](/molmil-images/mine/1ywr) | Crystal Structure Analysis of inactive P38 kinase domain in complex with a Monocyclic Pyrazolone Inhibitor | 分子名称: | 4-(4-FLUOROPHENYL)-1-METHYL-5-(2-{[(1S)-1-PHENYLETHYL]AMINO}PYRIMIDIN-4-YL)-2-PIPERIDIN-4-YL-1,2-DIHYDRO-3H-PYRAZOL-3-ONE, Mitogen-activated protein kinase 14 | 著者 | Golebiowski, A, Townes, J.A, Laufersweiler, M.J, Brugel, T.A, Clark, M.P, Clark, C.M, Djung, J.F, Laughlin, S.K, Sabat, M.P, Bookland, R.G, Vanrens, J.C, De, B, Hsieh, L.C, Janusz, M.J, Walter, R.L, Webster, M.E, Mekel, M.J. | 登録日 | 2005-02-18 | 公開日 | 2005-05-10 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | The development of monocyclic pyrazolone based cytokine synthesis inhibitors. Bioorg.Med.Chem.Lett., 15, 2005
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1U5J
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![BU of 1u5j by Molmil](/molmil-images/mine/1u5j) | Propionibacterium shermanii transcarboxylase 5S subunit, Met186Ile | 分子名称: | COBALT (II) ION, transcarboxylase 5S subunit | 著者 | Hall, P.R, Zheng, R, Antony, L, Pusztai-Carey, M, Carey, P.R, Yee, V.C. | 登録日 | 2004-07-27 | 公開日 | 2004-09-07 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Transcarboxylase 5S structures: assembly and catalytic mechanism of a multienzyme complex subunit. Embo J., 23, 2004
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8JOO
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![BU of 8joo by Molmil](/molmil-images/mine/8joo) | Crystal structure of cytochrome P450 IkaD from Streptomyces sp. ZJ306, in complex with the substrate ikarugamycin | 分子名称: | (1Z,3E,5S,7R,8R,10R,11R,12S,15R,16S,18Z,25S)-11-ethyl-2-hydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.05,16.07,15.08,12]octacosa-1(2),3,13,18-tetraene-20,27,28-trione, Cytochrome P450, FORMIC ACID, ... | 著者 | Zhang, Y.L, Zhang, L.P, Zhang, C.S. | 登録日 | 2023-06-08 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates. Angew.Chem.Int.Ed.Engl., 62, 2023
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5CPB
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![BU of 5cpb by Molmil](/molmil-images/mine/5cpb) | The effect of isoleucine to alanine mutation on InhA enzyme crystallization pattern and inhibition by ligand PT70 (TCU) | 分子名称: | Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE | 著者 | Li, H.-J, Lai, C.-T, Liu, N, Yu, W, Shah, S, Bommineni, G.R, Perrone, V, Garcia-Diaz, M, Tonge, P.J, Simmerling, C. | 登録日 | 2015-07-21 | 公開日 | 2015-08-19 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | Rational Modulation of the Induced-Fit Conformational Change for Slow-Onset Inhibition in Mycobacterium tuberculosis InhA. Biochemistry, 54, 2015
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3NFT
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![BU of 3nft by Molmil](/molmil-images/mine/3nft) | Near-atomic resolution analysis of BipD- A component of the type-III secretion system of Burkholderia pseudomallei | 分子名称: | Translocator protein bipD | 著者 | Pal, M, Erskine, P.T, Gill, R.S, Wood, S.P, Cooper, J.B. | 登録日 | 2010-06-10 | 公開日 | 2010-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | 主引用文献 | Near-atomic resolution analysis of BipD, a component of the type III secretion system of Burkholderia pseudomallei. Acta Crystallogr.,Sect.F, 66, 2010
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3D85
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![BU of 3d85 by Molmil](/molmil-images/mine/3d85) | Crystal structure of IL-23 in complex with neutralizing FAB | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, FAB of antibody 7G10, heavy chain, ... | 著者 | Beyer, B.M, Ingram, R, Ramanathan, L, Reichert, P, Le, H, Madison, V. | 登録日 | 2008-05-22 | 公開日 | 2008-09-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structures of the pro-inflammatory cytokine interleukin-23 and its complex with a high-affinity neutralizing antibody J.Mol.Biol., 382, 2008
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1CFP
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![BU of 1cfp by Molmil](/molmil-images/mine/1cfp) | |
8JNO
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![BU of 8jno by Molmil](/molmil-images/mine/8jno) | Crystal structure of cytochrome P450 IkaD from Streptomyces sp. ZJ306, in complex with the substrate 10-epi-deOH-HSAF | 分子名称: | (1Z,3E,5S,7S,8R,9S,10S,11R,13R,15R,16S,18Z,25S)-11-ethyl-2,7-dihydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.09,13.08,15.05,16]octacosa-1(2),3,18-triene-20,27,28-trione, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Zhang, Y.L, Zhang, L.P, Zhang, C.S. | 登録日 | 2023-06-06 | 公開日 | 2023-11-22 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | A Mechanistic Understanding of the Distinct Regio- and Chemoselectivity of Multifunctional P450s by Structural Comparison of IkaD and CftA Complexed with Common Substrates. Angew.Chem.Int.Ed.Engl., 62, 2023
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1Y7K
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![BU of 1y7k by Molmil](/molmil-images/mine/1y7k) | NMR structure family of Human Agouti Signalling Protein (80-132: Q115Y, S124Y) | 分子名称: | Agouti Signaling Protein | 著者 | McNulty, J.C, Jackson, P.J, Thompson, D.A, Chai, B, Gantz, I, Barsh, G.S, Dawson, P.E, Millhauser, G.L. | 登録日 | 2004-12-08 | 公開日 | 2005-02-15 | 最終更新日 | 2021-10-20 | 実験手法 | SOLUTION NMR | 主引用文献 | Structures of the agouti signaling protein. J.Mol.Biol., 346, 2005
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1Y81
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![BU of 1y81 by Molmil](/molmil-images/mine/1y81) | Conserved hypothetical protein Pfu-723267-001 from Pyrococcus furiosus | 分子名称: | COENZYME A, THIOCYANATE ION, UNKNOWN ATOM OR ION, ... | 著者 | Zhao, M, Chang, J, Habel, J, Xu, H, Chen, L, Lee, D, Nguyen, D, Chang, S.-H, Horanyi, P, Florence, Q, Tempel, W, Zhou, W, Lin, D, Zhang, H, Praissman, J, Jenney Jr, F.E, Adams, M.W.W, Liu, Z.-J, Rose, J.P, Wang, B.-C, Southeast Collaboratory for Structural Genomics (SECSG) | 登録日 | 2004-12-10 | 公開日 | 2005-01-25 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (1.701 Å) | 主引用文献 | Conserved hypothetical protein Pfu-723267-001 from Pyrococcus furiosus To be published
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3DEZ
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![BU of 3dez by Molmil](/molmil-images/mine/3dez) | Crystal structure of Orotate phosphoribosyltransferase from Streptococcus mutans | 分子名称: | Orotate phosphoribosyltransferase, SULFATE ION | 著者 | Liu, C.P, Gao, Z.Q, Hou, H.F, Li, L.F, Su, X.D, Dong, Y.H. | 登録日 | 2008-06-11 | 公開日 | 2009-06-16 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of orotate phosphoribosyltransferase from the caries pathogen Streptococcus mutans Acta Crystallogr.,Sect.F, 66, 2010
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5CUX
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![BU of 5cux by Molmil](/molmil-images/mine/5cux) | Crystal structure of N-terminal domain truncated Trypanosoma cruzi Vacuolar Soluble Pyrophosphatases in complex with PPi | 分子名称: | Acidocalcisomal pyrophosphatase, PHOSPHATE ION, PYROPHOSPHATE 2- | 著者 | Liu, W.D, Yang, Y.Y, Ko, T.P, Zheng, Y.Y, Chen, C.C, Guo, R.T. | 登録日 | 2015-07-25 | 公開日 | 2016-03-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structure of Trypanosoma cruzi protein in complex with ligand Acs Chem.Biol., 2016
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1Q1G
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![BU of 1q1g by Molmil](/molmil-images/mine/1q1g) | Crystal structure of Plasmodium falciparum PNP with 5'-methylthio-immucillin-H | 分子名称: | 3,4-DIHYDROXY-2-[(METHYLSULFANYL)METHYL]-5-(4-OXO-4,5-DIHYDRO-3H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)PYRROLIDINIUM, ISOPROPYL ALCOHOL, SULFATE ION, ... | 著者 | Shi, W, Ting, L.M, Kicska, G.A, Lewandowicz, A, Tyler, P.C, Evans, G.B, Furneaux, R.H, Kim, K, Almo, S.C, Schramm, V.L. | 登録日 | 2003-07-19 | 公開日 | 2004-03-16 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Plasmodium falciparum Purine Nucleoside Phosphorylase: CRYSTAL STRUCTURES, IMMUCILLIN INHIBITORS, AND DUAL CATALYTIC FUNCTION. J.Biol.Chem., 279, 2004
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2YGH
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![BU of 2ygh by Molmil](/molmil-images/mine/2ygh) | SAM-I riboswitch with a G2nA mutation in the Kink turn in complex with S-adenosylmethionine | 分子名称: | POTASSIUM ION, S-ADENOSYLMETHIONINE, SAM-I RIBOSWITCH, ... | 著者 | Schroeder, K, Daldrop, P, Lilley, D. | 登録日 | 2011-04-17 | 公開日 | 2011-09-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | RNA Tertiary Interactions in a Riboswitch Stabilize the Structure of a Kink Turn. Structure, 19, 2011
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2WSQ
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![BU of 2wsq by Molmil](/molmil-images/mine/2wsq) | MonoTIM mutant RMM0-1, dimeric form. | 分子名称: | SULFATE ION, TRIOSE PHOSPHATE ISOMERASE, GLYCOSOMAL | 著者 | Rudino-Pinera, E, Rojas-Trejo, S.P, Arreola, R, Saab-Rincon, G, Soberon, X, Horjales, E. | 登録日 | 2009-09-08 | 公開日 | 2009-09-15 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Space Group Transition Driven by Temperature and Related to Monomer-Dimer Transition in Solution: The Case of Monomeric Tim of Trypanosoma Brucei Brucei To be Published
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7E6Q
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![BU of 7e6q by Molmil](/molmil-images/mine/7e6q) | Crystal structure of influenza A virus neuraminidase N5 complexed with 4'-phenyl-1,2,3-triazolylated oseltamivir carboxylate | 分子名称: | (3R,4R,5S)-4-acetamido-3-pentan-3-yloxy-5-(4-phenyl-1,2,3-triazol-1-yl)cyclohexene-1-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Wang, P.F, Babayemi, O.O, Li, C.N, Fu, L.F, Zhang, S.S, Qi, J.X, Lv, X, Li, X.B. | 登録日 | 2021-02-23 | 公開日 | 2021-03-17 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-based design of 5'-substituted 1,2,3-triazolylated oseltamivir derivatives as potent influenza neuraminidase inhibitors. Rsc Adv, 11, 2021
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5MVG
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![BU of 5mvg by Molmil](/molmil-images/mine/5mvg) | Crystal structure of non-amyloidogenic light chain dimer M7 | 分子名称: | GLYCEROL, light chain dimer | 著者 | Oberti, L, Rognoni, P, Bacarizo, J, Bolognesi, M, Ricagno, S. | 登録日 | 2017-01-16 | 公開日 | 2017-12-13 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity. Sci Rep, 7, 2017
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5S8Q
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![BU of 5s8q by Molmil](/molmil-images/mine/5s8q) | XChem group deposition -- Crystal Structure of the second bromodomain of pleckstrin homology domain interacting protein (PHIP) in complex with FMO3D000185a (space group P212121) | 分子名称: | (3R)-3-methyl-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one, 1,2-ETHANEDIOL, CALCIUM ION, ... | 著者 | Krojer, T, Talon, R, Fairhead, M, Szykowska, A, Burgess-Brown, N.A, Brennan, P.E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, von Delft, F. | 登録日 | 2020-12-17 | 公開日 | 2021-01-13 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | XChem group deposition To Be Published
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3NI3
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![BU of 3ni3 by Molmil](/molmil-images/mine/3ni3) | 54-Membered ring macrocyclic beta-sheet peptide | 分子名称: | 54-membered ring macrocyclic beta-sheet peptide, ISOPROPYL ALCOHOL | 著者 | Sawaya, M.R, Eisenberg, D, Nowick, J.S, Korman, T.P, Khakshoor, O. | 登録日 | 2010-06-15 | 公開日 | 2010-09-15 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | X-ray crystallographic structure of an artificial beta-sheet dimer. J.Am.Chem.Soc., 132, 2010
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4CVI
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![BU of 4cvi by Molmil](/molmil-images/mine/4cvi) | Neutron Structure of Ferric Cytochrome c Peroxidase - Deuterium exchanged at room temperature | 分子名称: | CYTOCHROME C PEROXIDASE, MITOCHONDRIAL, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Casadei, C.M, Gumiero, A, Blakeley, M.P, Ostermann, A, Raven, E.L, Moody, P.C.E. | 登録日 | 2014-03-27 | 公開日 | 2014-07-16 | 最終更新日 | 2024-05-08 | 実験手法 | NEUTRON DIFFRACTION (2.1 Å), X-RAY DIFFRACTION | 主引用文献 | Neutron Cryo-Crystallography Captures the Protonation State of Ferryl Heme in a Peroxidase Science, 345, 2014
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8K4X
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![BU of 8k4x by Molmil](/molmil-images/mine/8k4x) | Structure of a triple-helix region of human Collagen type XVII from Trautec | 分子名称: | triple-helix region of human Collagen type XVII | 著者 | Chu, Y, Zhai, Y, Fan, X, Li, J, Wang, L, Fu, S, Feng, P, Qian, S. | 登録日 | 2023-07-20 | 公開日 | 2023-08-02 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Structure of a triple-helix region of human Collagen type XVII from Trautec. To Be Published
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5MX9
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![BU of 5mx9 by Molmil](/molmil-images/mine/5mx9) | High resolution crystal structure of the MCR-2 catalytic domain | 分子名称: | GLYCEROL, Phosphatidylethanolamine transferase Mcr-2, ZINC ION | 著者 | Hinchliffe, P, Coates, K, Walsh, T.R, Spencer, J. | 登録日 | 2017-01-22 | 公開日 | 2017-08-09 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.12 Å) | 主引用文献 | 1.12 angstrom resolution crystal structure of the catalytic domain of the plasmid-mediated colistin resistance determinant MCR-2. Acta Crystallogr F Struct Biol Commun, 73, 2017
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