5S8Q

XChem group deposition -- Crystal Structure of the second bromodomain of pleckstrin homology domain interacting protein (PHIP) in complex with FMO3D000185a (space group P212121)

Summary for 5S8Q

• Entry DOI: 10.2210/pdb5s8q/pdb
• Group deposition: XChem group deposition (G_1002187)
• Descriptor: PH-interacting protein, CALCIUM ION, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: sgc - diamond i04-1 fragment screening, bromodomain, phip, xchemexplorer, signaling protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 31105.36

Authors

Krojer, T.,Talon, R.,Fairhead, M.,Szykowska, A.,Burgess-Brown, N.A.,Brennan, P.E.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F. (deposition date: 2020-12-17, release date: 2021-01-13, Last modification date: 2024-03-06)

• Primary citation: Krojer, T.,Talon, R.,Fairhead, M.,Szykowska, A.,Burgess-Brown, N.A.,Brennan, P.E.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,von Delft, F.; XChem group deposition; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.5 Å)