5S8Q
XChem group deposition -- Crystal Structure of the second bromodomain of pleckstrin homology domain interacting protein (PHIP) in complex with FMO3D000185a (space group P212121)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PH-interacting protein | polymer | 128 | 15156.2 | 2 | UniProt (Q8WWQ0) Pfam (PF00439) | Homo sapiens (Human) | PHIP,DDB1- and CUL4-associated factor 14,IRS-1 PH domain-binding protein,WD repeat-containing protein 11 |
| 2 | C, G, H (A, B) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 3 | D, E, I, J, K... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 4 | F (B) | (3R)-3-methyl-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one | non-polymer | 176.2 | 1 | Chemie (XLY) | |||
| 5 | O, P (A, B) | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A, B: 1315 - 1440 (UniProt: Q8WWQ0)
| PDB | External Database | Details |
|---|---|---|
| Ser 1313 | - | expression tag |
| Met 1314 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30312.4 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 793.0 | |
| All* | Total formula weight | 31105.4 |
