8T62
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8T61
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8T63
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2YFU
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![BU of 2yfu by Molmil](/molmil-images/mine/2yfu) | CBM62 FROM CLOSTRIDIUM THERMOCELLUM XYL5A | 分子名称: | CALCIUM ION, CARBOHYDRATE BINDING FAMILY 6, GLYCEROL | 著者 | Montanier, C.Y, Correia, M.A.S, Flint, J.E, Zhu, Y, Basle, A, Mckee, L.S, Prates, J.A.M, Polizzi, S.J, Coutinho, P.M, Henrissat, B, Fontes, C.M.G.A, Gilbert, H.J. | 登録日 | 2011-04-08 | 公開日 | 2011-05-18 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | A Novel, Noncatalytic Carbohydrate-Binding Module Displays Specificity for Galactose-Containing Polysaccharides Through Calcium-Mediated Oligomerization. J.Biol.Chem., 286, 2011
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4UBN
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![BU of 4ubn by Molmil](/molmil-images/mine/4ubn) | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 1.85 MGy TEMP 150K | 分子名称: | DIETHYL HYDROGEN PHOSPHATE, E3 | 著者 | Jackson, C.J, Carr, P.D, Weik, M, Huber, T, Meirelles, T, Correy, G. | 登録日 | 2014-08-13 | 公開日 | 2015-08-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography Structure, 24, 2016
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8T5K
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![BU of 8t5k by Molmil](/molmil-images/mine/8t5k) | Crystal structure of STING CTD in complex with BDW-OH | 分子名称: | Stimulator of interferon genes protein, {[(4S)-8,9-dimethylthieno[3,2-e][1,2,4]triazolo[4,3-c]pyrimidin-3-yl]sulfanyl}acetic acid | 著者 | Li, Y, Li, P, Sun, D. | 登録日 | 2023-06-13 | 公開日 | 2023-07-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural and Biological Evaluations of a Non-Nucleoside STING Agonist Specific for Human STING A230 Variants. Biorxiv, 2023
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2YCX
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![BU of 2ycx by Molmil](/molmil-images/mine/2ycx) | TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND ANTAGONIST CYANOPINDOLOL | 分子名称: | 4-{[(2S)-3-(tert-butylamino)-2-hydroxypropyl]oxy}-3H-indole-2-carbonitrile, BETA-1 ADRENERGIC RECEPTOR, octyl 1-thio-beta-D-glucopyranoside | 著者 | Moukhametzianov, R, Warne, T, Edwards, P.C, Serrano-Vega, M.J, Leslie, A.G.W, Tate, C.G, Schertler, G.F.X. | 登録日 | 2011-03-17 | 公開日 | 2011-06-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Two Distinct Conformations of Helix 6 Observed in Antagonist-Bound Structures of a Beta-1- Adrenergic Receptor. Proc.Natl.Acad.Sci.USA, 108, 2011
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4UBI
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![BU of 4ubi by Molmil](/molmil-images/mine/4ubi) | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 3.70 MGy at 100K | 分子名称: | DIETHYL HYDROGEN PHOSPHATE, E3 | 著者 | Jackson, C.J, Carr, P.D, Weik, M, Huber, T, Meirelles, T, Correy, G. | 登録日 | 2014-08-13 | 公開日 | 2015-08-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography Structure, 24, 2016
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4UBF
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![BU of 4ubf by Molmil](/molmil-images/mine/4ubf) | HsMCAK motor domain complex | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Kinesin-like protein KIF2C, MAGNESIUM ION | 著者 | Welburn, J.P.I, Talapatra, S.K. | 登録日 | 2014-08-12 | 公開日 | 2015-05-06 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch. Elife, 4, 2015
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4UOA
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![BU of 4uoa by Molmil](/molmil-images/mine/4uoa) | Structure of the A_Canine_Colorado_17864_06 H3 haemagglutinin Met29Ile mutant | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HA1, ... | 著者 | Vachieri, S.G, Collins, P.J, Haire, L.F, Ogrodowicz, R.W, Martin, S.R, Walker, P.A, Xiong, X, Gamblin, S.J, Skehel, J.J. | 登録日 | 2014-05-31 | 公開日 | 2014-07-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Recent Evolution of Equine Influenza and the Origin of Canine Influenza. Proc.Natl.Acad.Sci.USA, 111, 2014
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4UBL
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![BU of 4ubl by Molmil](/molmil-images/mine/4ubl) | KINETIC CRYSTALLOGRAPHY OF ALPHA_E7-CARBOXYLESTERSE FROM LUCILLA CUPRINA - ABSORBED X-RAY DOSE 9.26 MGy | 分子名称: | DIETHYL HYDROGEN PHOSPHATE, E3 | 著者 | Jackson, C.J, Carr, P.D, Weik, M, Huber, T, Meirelles, T, Correy, G. | 登録日 | 2014-08-13 | 公開日 | 2015-08-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography Structure, 24, 2016
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4UOV
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![BU of 4uov by Molmil](/molmil-images/mine/4uov) | The structure of a tetrameric alpha-carbonic anhydrase from Thermovibrio ammonificans reveals a core formed around intermolecular disulfides, which contribute to its thermostability. | 分子名称: | 1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, ... | 著者 | James, P, Isupov, M, Sayer, C, Berg, S, Lioliou, M, Kotlar, H, Littlechild, J. | 登録日 | 2014-06-10 | 公開日 | 2014-10-15 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The Structure of a Tetrameric [Alpha]-Carbonic Anhydrase from Thermovibrio Ammonificans Reveals a Core Formed Around Intermolecular Disulfides that Contribute to its Thermostability Acta Crystallogr.,Sect.D, 70, 2014
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4UO9
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![BU of 4uo9 by Molmil](/molmil-images/mine/4uo9) | Structure of the A_Canine_Colorado_17864_06 H3 haemagglutinin Ser30Thr mutant | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HA1, ... | 著者 | Vachieri, S.G, Collins, P.J, Haire, L.F, Ogrodowicz, R.W, Martin, S.R, Walker, P.A, Xiong, X, Gamblin, S.J, Skehel, J.J. | 登録日 | 2014-05-31 | 公開日 | 2014-07-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Recent Evolution of Equine Influenza and the Origin of Canine Influenza. Proc.Natl.Acad.Sci.USA, 111, 2014
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4UCG
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![BU of 4ucg by Molmil](/molmil-images/mine/4ucg) | NmeDAH7PS R126S variant | 分子名称: | DI(HYDROXYETHYL)ETHER, MANGANESE (II) ION, PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE, ... | 著者 | Cross, P.J, Heyes, L.C, Zhang, S, Nazmi, A.R, Parker, E.J. | 登録日 | 2014-12-03 | 公開日 | 2016-01-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Functional Unit of Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase is Dimeric. Plos One, 11, 2016
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4UMA
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![BU of 4uma by Molmil](/molmil-images/mine/4uma) | Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3 deoxy D arabino heptulosonate 7 phosphate synthase the importance of accommodating the active site water | 分子名称: | (E)-2-METHYL-3-PHOSPHONOACRYLATE, MANGANESE (II) ION, PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE | 著者 | Heyes, L.C, Reichau, S, Cross, P.J, Parker, E.J. | 登録日 | 2014-05-16 | 公開日 | 2014-10-08 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | Structural Analysis of Substrate-Mimicking Inhibitors in Complex with Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase - the Importance of Accommodating the Active Site Water. Bioorg.Chem., 57, 2014
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4V2O
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![BU of 4v2o by Molmil](/molmil-images/mine/4v2o) | Structure of saposin B in complex with chloroquine | 分子名称: | N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE, SAPOSIN-B | 著者 | Zubieta, C, Lai, X, Doyle, R.P. | 登録日 | 2014-10-13 | 公開日 | 2015-12-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.13 Å) | 主引用文献 | The Lysosomal Protein Saposin B Binds Chloroquine. Chemmedchem, 11, 2016
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4UY2
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![BU of 4uy2 by Molmil](/molmil-images/mine/4uy2) | Crystal structure of the complex of the extracellular domain of human alpha9 nAChR with alpha-bungarotoxin. | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ALPHA-BUNGAROTOXIN ISOFORM V31, NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-9 | 著者 | Giastas, P, Zouridakis, M, Zarkadas, E, Tzartos, S.J. | 登録日 | 2014-08-28 | 公開日 | 2014-10-01 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.697 Å) | 主引用文献 | Crystal Structures of Free and Antagonist-Bound States of Human Alpha9 Nicotinic Receptor Extracellular Domain Nat.Struct.Mol.Biol., 21, 2014
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4V98
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![BU of 4v98 by Molmil](/molmil-images/mine/4v98) | The 8S snRNP Assembly Intermediate | 分子名称: | CG10419, Icln, LD23602p, ... | 著者 | Grimm, C, Pelz, J.P, Schindelin, H, Diederichs, K, Kuper, J, Kisker, C. | 登録日 | 2012-05-15 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural Basis of Assembly Chaperone- Mediated snRNP Formation. Mol.Cell, 49, 2013
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5CSH
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![BU of 5csh by Molmil](/molmil-images/mine/5csh) | Crystal Structure of CK2alpha with Compound 4 bound | 分子名称: | 1-(2-chlorobiphenyl-4-yl)methanamine, ACETATE ION, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Brear, P, De Fusco, C, Georgiou, K.H, Spring, D, Hyvonen, M. | 登録日 | 2015-07-23 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | 主引用文献 | Specific inhibition of CK2 alpha from an anchor outside the active site. Chem Sci, 7, 2016
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6QBH
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![BU of 6qbh by Molmil](/molmil-images/mine/6qbh) | Crystal structure of human cathepsin D in complex with macrocyclic inhibitor 33 | 分子名称: | (4~{S},5~{S},9~{S})-5-oxidanyl-4-(phenylmethyl)-9-propan-2-yl-1-oxa-3,8,11-triazacyclodocosane-2,7,10-trione, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Brynda, J, Houstecka, R, Majer, P, Mares, M. | 登録日 | 2018-12-21 | 公開日 | 2020-01-29 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Biomimetic Macrocyclic Inhibitors of Human Cathepsin D: Structure-Activity Relationship and Binding Mode Analysis. J.Med.Chem., 63, 2020
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8DQK
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![BU of 8dqk by Molmil](/molmil-images/mine/8dqk) | Intermediate resolution structure of barley (1,3;1,4)-beta-glucan synthase CslF6. | 分子名称: | Cellulose synthase-like CslF6 | 著者 | Ho, R, Purushotham, P, Zimmer, J. | 登録日 | 2022-07-19 | 公開日 | 2022-11-30 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Mechanism of mixed-linkage glucan biosynthesis by barley cellulose synthase-like CslF6 (1,3;1,4)-beta-glucan synthase. Sci Adv, 8, 2022
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6DB2
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![BU of 6db2 by Molmil](/molmil-images/mine/6db2) | X-ray crystal structure of VioC bound to vanadyl ion, L-homoarginine, and succinate | 分子名称: | 1,2-ETHANEDIOL, Alpha-ketoglutarate-dependent L-arginine hydroxylase, L-HOMOARGININE, ... | 著者 | Dunham, N.P, Mitchell, A.J, Boal, A.K. | 登録日 | 2018-05-02 | 公開日 | 2018-05-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of alpha-Heteroatom Assistance. J. Am. Chem. Soc., 140, 2018
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8DW2
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![BU of 8dw2 by Molmil](/molmil-images/mine/8dw2) | Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR22, and two antibody Fabs, S309 and CR3022 | 分子名称: | Antibody CR3022 heavy chain, Antibody CR3022 light chain, Antibody S309 heavy chain, ... | 著者 | Kwon, Y.D, Gorman, J, Kwong, P.D. | 登録日 | 2022-07-30 | 公開日 | 2022-12-07 | 最終更新日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (4.11 Å) | 主引用文献 | A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins. Nat.Chem.Biol., 19, 2023
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8DW3
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![BU of 8dw3 by Molmil](/molmil-images/mine/8dw3) | Cryo-EM structure of SARS-CoV-2 RBD in complex with anti-SARS-CoV-2 DARPin,SR16m, and two antibody Fabs, S309 and CR3022 | 分子名称: | Anti-SARS-CoV-2 DARPin SR16m, Antibody S309 light chain, Spike protein S1, ... | 著者 | Kwon, Y.D, Gorman, J, Kwong, P.D. | 登録日 | 2022-07-30 | 公開日 | 2022-12-07 | 最終更新日 | 2023-03-15 | 実験手法 | ELECTRON MICROSCOPY (4.26 Å) | 主引用文献 | A potent and broad neutralization of SARS-CoV-2 variants of concern by DARPins. Nat.Chem.Biol., 19, 2023
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5DBF
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![BU of 5dbf by Molmil](/molmil-images/mine/5dbf) | Crystal Structure of Iridoid Synthase from Cantharanthus roseus in complex with NADPH | 分子名称: | Iridoid synthase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Hu, Y.M, Liu, W.D, Zheng, Y.Y, Xu, Z.X, Ko, T.P, Chen, C.C, Guo, R.T. | 登録日 | 2015-08-21 | 公開日 | 2015-11-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of Iridoid Synthase from Cantharanthus roseus with Bound NAD(+) , NADPH, or NAD(+) /10-Oxogeranial: Reaction Mechanisms Angew.Chem.Int.Ed.Engl., 54, 2015
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