2PVK
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![BU of 2pvk by Molmil](/molmil-images/mine/2pvk) | Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 | 分子名称: | 2-(4-CHLOROBENZYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[1,5-A][1,3,5]TRIAZINE-8-CARBONITRILE, Casein kinase II subunit alpha | 著者 | Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. | 登録日 | 2007-05-09 | 公開日 | 2008-05-13 | 最終更新日 | 2021-10-20 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
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2EFO
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![BU of 2efo by Molmil](/molmil-images/mine/2efo) | Crystal structure of Tyr77 to Ala of ST1022 from Sulfolobus tokodaii 7 | 分子名称: | 150aa long hypothetical transcriptional regulator, MAGNESIUM ION | 著者 | Kumarevel, T.S, Karthe, P, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-02-23 | 公開日 | 2008-02-26 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding. Nucleic Acids Res., 36, 2008
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2EFQ
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![BU of 2efq by Molmil](/molmil-images/mine/2efq) | Crystal Structure of Thr134 to Ala of ST1022-Glutamine Complex from Sulfolobus tokodaii 7 | 分子名称: | 150aa long hypothetical transcriptional regulator, GLUTAMINE, MAGNESIUM ION | 著者 | Kumarevel, T.S, Karthe, P, Nakano, N, Shinkai, A, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-02-23 | 公開日 | 2008-03-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of glutamine receptor protein from Sulfolobus tokodaii strain 7 in complex with its effector L-glutamine: implications of effector binding in molecular association and DNA binding. Nucleic Acids Res., 36, 2008
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2PH9
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![BU of 2ph9 by Molmil](/molmil-images/mine/2ph9) | Galanthamine bound to an ACh-binding Protein | 分子名称: | (-)-GALANTHAMINE, Soluble acetylcholine receptor, TETRAETHYLENE GLYCOL | 著者 | Hansen, S.B, Taylor, P. | 登録日 | 2007-04-10 | 公開日 | 2007-07-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.88 Å) | 主引用文献 | Galanthamine and non-competitive inhibitor binding to ACh-binding protein: evidence for a binding site on non-alpha-subunit interfaces of heteromeric neuronal nicotinic receptors. J.Mol.Biol., 369, 2007
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2PKG
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![BU of 2pkg by Molmil](/molmil-images/mine/2pkg) | |
2PSX
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2EF0
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![BU of 2ef0 by Molmil](/molmil-images/mine/2ef0) | Crystal structure of ornithine carbamoyltransferase from thermus thermophilus | 分子名称: | MAGNESIUM ION, Ornithine carbamoyltransferase, SODIUM ION | 著者 | Karthe, P, Kumarevel, T.S, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-02-19 | 公開日 | 2007-04-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of ornithine carbamoyltransferase from thermus thermophilus To be Published
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1AGO
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3U2D
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![BU of 3u2d by Molmil](/molmil-images/mine/3u2d) | S. aureus GyrB ATPase domain in complex with small molecule inhibitor | 分子名称: | 4-bromo-5-methyl-N-[1-(3-nitropyridin-2-yl)piperidin-4-yl]-1H-pyrrole-2-carboxamide, DNA gyrase subunit B, MAGNESIUM ION | 著者 | Boriack-Sjodin, P.A, Prince, D.B, Eakin, A.E, Sherer, B.A. | 登録日 | 2011-10-03 | 公開日 | 2012-01-11 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Pyrrolamide DNA gyrase inhibitors: fragment-based nuclear magnetic resonance screening to identify antibacterial agents. Antimicrob.Agents Chemother., 56, 2012
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6M84
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![BU of 6m84 by Molmil](/molmil-images/mine/6m84) | Crystal structure of cKir2.2 force open mutant in complex with PI(4,5)P2 | 分子名称: | ATP-sensitive inward rectifier potassium channel 12, DODECYL-BETA-D-MALTOSIDE, POTASSIUM ION, ... | 著者 | Lee, S.-J, Ren, F, Yuan, P, Nichols, C.G. | 登録日 | 2018-08-21 | 公開日 | 2019-09-04 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels. J.Gen.Physiol., 152, 2020
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2PVH
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![BU of 2pvh by Molmil](/molmil-images/mine/2pvh) | Structure-Based Design of Pyrazolo[1,5-a][1,3,5]triazine Derivatives as Potent Inhibitors of Protein Kinase CK2 | 分子名称: | Casein kinase II subunit alpha, N,N'-DIPHENYLPYRAZOLO[1,5-A][1,3,5]TRIAZINE-2,4-DIAMINE | 著者 | Nie, Z, Perretta, C, Erickson, P, Margosiak, S, Almassy, R, Lu, J, Averill, A, Yager, K.M, Chu, S. | 登録日 | 2007-05-09 | 公開日 | 2008-05-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-based design, synthesis, and study of pyrazolo[1,5-a][1,3,5]triazine derivatives as potent inhibitors of protein kinase CK2. Bioorg.Med.Chem.Lett., 17, 2007
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1A0L
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![BU of 1a0l by Molmil](/molmil-images/mine/1a0l) | HUMAN BETA-TRYPTASE: A RING-LIKE TETRAMER WITH ACTIVE SITES FACING A CENTRAL PORE | 分子名称: | (2S)-3-(4-carbamimidoylphenyl)-2-hydroxypropanoic acid, BETA-TRYPTASE | 著者 | Pereira, P.J.B, Bergner, A, Macedo-Ribeiro, S, Huber, R, Matschiner, G, Fritz, H, Sommerhoff, C.P, Bode, W. | 登録日 | 1997-12-03 | 公開日 | 1999-03-23 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Human beta-tryptase is a ring-like tetramer with active sites facing a central pore. Nature, 392, 1998
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4U2V
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![BU of 4u2v by Molmil](/molmil-images/mine/4u2v) | Bak BH3-in-Groove dimer (GFP) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, CACODYLATE ION, Green fluorescent protein,Bcl-2 homologous antagonist/killer | 著者 | Brouwer, J.M, Colman, P.M, Czabotar, P.E. | 登録日 | 2014-07-18 | 公開日 | 2014-09-10 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers. Mol.Cell, 55, 2014
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2DXY
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![BU of 2dxy by Molmil](/molmil-images/mine/2dxy) | Structure of the complex of C-terminal lobe of bovine lactoferrin with trehalose at 2.0 A resolution | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CARBONATE ION, FE (III) ION, ... | 著者 | Mir, R, Singh, N, Sinha, M, Sharma, S, Bhushan, A, Singh, T.P. | 登録日 | 2006-09-03 | 公開日 | 2006-09-19 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | 主引用文献 | Structure of the complex of C-terminal lobe of bovine lactoferrin with trehalose at 2.0 A resolution To be Published
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2EQF
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![BU of 2eqf by Molmil](/molmil-images/mine/2eqf) | Solution structure of the 7th A20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3 | 分子名称: | Tumor necrosis factor, alpha-induced protein 3, ZINC ION | 著者 | Zhang, H.P, Hayahsi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-30 | 公開日 | 2007-10-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the 7th A20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3 To be Published
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2EQE
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![BU of 2eqe by Molmil](/molmil-images/mine/2eqe) | Solution structure of the fourth A20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3 | 分子名称: | Tumor necrosis factor, alpha-induced protein 3, ZINC ION | 著者 | Zhang, H.P, Nagasima, T, Hayahsi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-03-30 | 公開日 | 2007-10-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the fourth A20-type zinc finger domain from human tumor necrosis factor, alpha-induced protein3 To be Published
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2EOT
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![BU of 2eot by Molmil](/molmil-images/mine/2eot) | SOLUTION STRUCTURE OF EOTAXIN, AN ENSEMBLE OF 32 NMR SOLUTION STRUCTURES | 分子名称: | EOTAXIN | 著者 | Crump, M.P, Rajarathnam, K, Kim, K.-S, Clark-Lewis, I, Sykes, B.D. | 登録日 | 1998-06-29 | 公開日 | 1998-11-11 | 最終更新日 | 2022-03-09 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of eotaxin, a chemokine that selectively recruits eosinophils in allergic inflammation. J.Biol.Chem., 273, 1998
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1A4D
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![BU of 1a4d by Molmil](/molmil-images/mine/1a4d) | LOOP D/LOOP E ARM OF ESCHERICHIA COLI 5S RRNA, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | RNA (5'-R(*GP*GP*CP*CP*GP*AP*UP*GP*GP*UP*AP*GP*UP*GP*UP*GP*GP*GP*GP*UP*C)-3'), RNA (5'-R(P*UP*CP*CP*CP*CP*AP*UP*GP*CP*GP*AP*GP*AP*GP*UP*AP*GP*GP*CP*C)-3') | 著者 | Dallas, A, Moore, P.B. | 登録日 | 1998-01-29 | 公開日 | 1998-04-29 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The loop E-loop D region of Escherichia coli 5S rRNA: the solution structure reveals an unusual loop that may be important for binding ribosomal proteins. Structure, 5, 1997
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4UG0
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![BU of 4ug0 by Molmil](/molmil-images/mine/4ug0) | STRUCTURE OF THE HUMAN 80S RIBOSOME | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S RIBOSOMAL PROTEIN, ... | 著者 | Khatter, H, Myasnikov, A.G, Natchiar, S.K, Klaholz, B.P. | 登録日 | 2015-03-20 | 公開日 | 2015-06-10 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure of the human 80S ribosome NATURE, 520, 2015
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4UCW
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![BU of 4ucw by Molmil](/molmil-images/mine/4ucw) | Structure of the T18V small subunit mutant of D. fructosovorans NiFe- hydrogenase | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, GLYCEROL, ... | 著者 | Abou-Hamdan, A, Ceccaldi, P, Lebrette, H, Guttierez-Sanz, O, Richaud, P, Cournac, L, Guigliarelli, B, deLacey, A.L, Leger, C, Volbeda, A, Burlat, B, Dementin, S. | 登録日 | 2014-12-04 | 公開日 | 2015-02-18 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A Threonine Stabilizes the Nic and Nir Catalytic Intermediates of [Nife]-Hydrogenase. J.Biol.Chem., 290, 2015
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4UE2
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![BU of 4ue2 by Molmil](/molmil-images/mine/4ue2) | Structure of air-treated anaerobically purified D. fructosovorans NiFe-hydrogenase | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, GLYCEROL, ... | 著者 | Volbeda, A, Martin, L, Liebgott, P.-P, Fontecilla-Camps, J.C. | 登録日 | 2014-12-15 | 公開日 | 2015-03-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | [Nife]-Hydrogenases Revisited: Nickel-Carboxamido Bond Formation in a Variant with Accrued O2-Tolerance and a Tentative Re-Interpretation of Ni-Si States. Metallomics, 7, 2015
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4UMM
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![BU of 4umm by Molmil](/molmil-images/mine/4umm) | The Cryo-EM structure of the palindromic DNA-bound USP-EcR nuclear receptor reveals an asymmetric organization with allosteric domain positioning | 分子名称: | 2,3,14,20,22-PENTAHYDROXYCHOLEST-7-EN-6-ONE, 5'-D(*CP*AP*AP*GP*GP*GP*TP*TP*CP*AP*AP*TP*GP*CP *AP*CP*TP*TP*GP*TP)-3', 5'-D(*DGP*AP*CP*AP*AP*GP*TP*GP*CP*AP*TP*TP*GP*DAP *AP*CP*CP*CP*TP*T)-3', ... | 著者 | Maletta, M, Orlov, I, Moras, D, Billas, I.M.L, Klaholz, B.P. | 登録日 | 2014-05-19 | 公開日 | 2014-06-25 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (11.6 Å) | 主引用文献 | The Palindromic DNA-Bound Usp-Ecr Nuclear Receptor Adopts an Asymmetric Organization with Allosteric Domain Positioning. Nat.Commun., 5, 2014
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1AGZ
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4UD2
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![BU of 4ud2 by Molmil](/molmil-images/mine/4ud2) | Structure of anaerobically purified D. fructosovorans NiFe- hydrogenase | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, GLYCEROL, ... | 著者 | Volbeda, A, Martin, L, Liebgott, P.-P, Fontecilla-Camps, J.C. | 登録日 | 2014-12-05 | 公開日 | 2015-03-25 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | [Nife]-Hydrogenases Revisited: Nickel-Carboxamido Bond Formation in a Variant with Accrued O2-Tolerance and a Tentative Re-Interpretation of Ni-Si States. Metallomics, 7, 2015
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4UN8
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![BU of 4un8 by Molmil](/molmil-images/mine/4un8) | THE CRYSTAL STRUCTURE OF I-DMOI IN COMPLEX WITH ITS TARGET DNA AT 1H INCUBATION IN 5MM MN (STATE 2) | 分子名称: | 25MER, HOMING ENDONUCLEASE I-DMOI, MANGANESE (II) ION | 著者 | Molina, R, Stella, S, Redondo, P, Gomez, H, Marcaida, M.J, Orozco, M, Prieto, J, Montoya, G. | 登録日 | 2014-05-26 | 公開日 | 2014-12-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Visualizing Phosphodiester-Bond Hydrolysis by an Endonuclease. Nat.Struct.Mol.Biol., 22, 2015
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