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PDB: 7397 件

3QYN
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Structure of p63 DNA Binding Domain in Complex with a 22 Base Pair A/T Rich Response Element Containing 2 Base Pair Spacer Between Half Sites
分子名称: 5'-D(*AP*AP*AP*CP*AP*TP*GP*TP*TP*TP*TP*AP*AP*AP*AP*CP*AP*TP*GP*TP*TP*T)-3', Tumor protein 63, ZINC ION
著者Chen, C, Herzberg, O.
登録日2011-03-03
公開日2011-04-06
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of p63 DNA binding domain in complexes with half-site and with spacer-containing full response elements.
Proc.Natl.Acad.Sci.USA, 108, 2011
5ONA
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Drosophila Bag-of-marbles CBM peptide bound to human CAF40-CNOT1
分子名称: CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 9, CHLORIDE ION, ...
著者Raisch, T, Sgromo, A, Backhaus, C, Izaurralde, E, Weichenrieder, O.
登録日2017-08-03
公開日2017-12-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献DrosophilaBag-of-marbles directly interacts with the CAF40 subunit of the CCR4-NOT complex to elicit repression of mRNA targets.
RNA, 24, 2018
3QXY
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Human SETD6 in complex with RelA Lys310
分子名称: 1,2-ETHANEDIOL, N-lysine methyltransferase SETD6, S-ADENOSYLMETHIONINE, ...
著者Chang, Y, Levy, D, Horton, J.R, Peng, J, Zhang, X, Gozani, O, Cheng, X.
登録日2011-03-02
公開日2011-05-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling.
Nucleic Acids Res., 39, 2011
5OQL
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BU of 5oql by Molmil
Cryo-EM structure of the 90S pre-ribosome from Chaetomium thermophilum
分子名称: 35S rRNA, 40S ribosomal protein S1, 40S ribosomal protein S11-like protein, ...
著者Cheng, J, Kellner, N, Berninghausen, O, Hurt, E, Beckmann, R.
登録日2017-08-12
公開日2017-10-11
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献3.2- angstrom -resolution structure of the 90S preribosome before A1 pre-rRNA cleavage.
Nat. Struct. Mol. Biol., 24, 2017
3QKZ
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Crystal structure of mutant His269Arg AKR1B14
分子名称: Aldo-keto reductase family 1, member B7, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Sundaram, K, El-Kabbani, O.
登録日2011-02-02
公開日2012-02-29
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structure of the His269Arg mutant of the rat aldose reductase-like protein AKR1B14 complexed with NADPH.
Acta Crystallogr.,Sect.F, 68, 2012
5MTK
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Crystal structure of human Caspase-1 with (3S,6S,10aS)-N-((2S,3S)-2-hydroxy-5-oxotetrahydrofuran-3-yl)-6-(isoquinoline-1-carboxamido)-5-oxodecahydropyrrolo[1,2-a]azocine-3-carboxamide (PGE-3935199)
分子名称: (3~{S})-3-[[(3~{S},6~{S},10~{a}~{S})-6-(isoquinolin-1-ylcarbonylamino)-5-oxidanylidene-2,3,6,7,8,9,10,10~{a}-octahydro-1~{H}-pyrrolo[1,2-a]azocin-3-yl]carbonylamino]-4-oxidanyl-butanoic acid, Caspase-1
著者Brethon, A, Chantalat, L, Christin, O, Clary, L, Fournier, J.F, Gastreich, M, Harris, C, Pascau, J, Isabet, T, Rodeschin, V, Thoreau, E, Roche, D.
登録日2017-01-09
公開日2018-02-28
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Playing against the odds: scaffold hopping from 3D-fragments
To Be Published
5MVF
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Active structure of EHD4 complexed with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, EH domain-containing protein 4, MAGNESIUM ION
著者Melo, A.A, Daumke, O.
登録日2017-01-16
公開日2017-03-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.268 Å)
主引用文献Structural insights into the activation mechanism of dynamin-like EHD ATPases.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
3QFG
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Structure of a putative lipoprotein from Staphylococcus aureus subsp. aureus NCTC 8325
分子名称: Uncharacterized protein
著者Filippova, E.V, Halavaty, A, Shuvalova, L, Minasov, G, Dubrovska, I, Winsor, J, Kiryukhina, O, Papazisi, L, Bagnoli, F, Falugi, F, Bottomley, M, Grandi, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2011-01-21
公開日2011-02-02
最終更新日2017-11-08
実験手法X-RAY DIFFRACTION (3.08 Å)
主引用文献Structure of a putative lipoprotein from Staphylococcus aureus subsp. aureus NCTC 8325
To be Published
5MEL
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BU of 5mel by Molmil
Structure of an E333Q variant of the GH99 endo-alpha-mannanase from Bacteroides xylanisolvens in complex with Glc-alpha-1,3-(3R,4R,5R)-5-(hydroxymethyl)cyclohex-1,2-ene-3,4-diol
分子名称: (1~{R},2~{R},6~{R})-6-(hydroxymethyl)cyclohex-3-ene-1,2-diol, ACETATE ION, Glycosyl hydrolase family 71, ...
著者Petricevic, M, Sobala, L.F, Fernandes, P.Z, Raich, L, Thompson, A.J, Bernardo-Seisdedos, G, Millet, O, Zhu, S, Sollogoub, M, Rovira, C, Jimenez-Barbero, J, Davies, G.J, Williams, S.J.
登録日2016-11-15
公開日2017-01-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-alpha-1,2-Mannanase.
J. Am. Chem. Soc., 139, 2017
5MGY
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BU of 5mgy by Molmil
Crystal structure of Pseudomonas stutzeri flavinyl transferase ApbE, apo form
分子名称: FAD:protein FMN transferase, MAGNESIUM ION
著者Zhang, L, Trncik, C, Andrade, S.L.A, Einsle, O.
登録日2016-11-22
公開日2016-12-14
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The flavinyl transferase ApbE of Pseudomonas stutzeri matures the NosR protein required for nitrous oxide reduction.
Biochim. Biophys. Acta, 1858, 2016
3QM3
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1.85 Angstrom Resolution Crystal Structure of Fructose-bisphosphate Aldolase (Fba) from Campylobacter jejuni
分子名称: CHLORIDE ION, FORMIC ACID, Fructose-bisphosphate aldolase, ...
著者Minasov, G, Wawrzak, Z, Skarina, T, Onopriyenko, O, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2011-02-03
公開日2011-02-23
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献1.85 Angstrom Resolution Crystal Structure of Fructose-bisphosphate Aldolase (Fba) from Campylobacter jejuni
TO BE PUBLISHED
3RKG
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BU of 3rkg by Molmil
Structural and Functional Characterization of the Yeast Mg2+ Channel Mrs2
分子名称: 1,2-ETHANEDIOL, Magnesium transporter MRS2, mitochondrial
著者Khan, M.B, Sponder, G, Sjoeblom, B, Svidova, S, Schweyen, R.J, Carugo, O, Djinovic-Carugo, K.
登録日2011-04-18
公開日2012-04-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.28 Å)
主引用文献Structural and functional characterization of the N-terminal domain of the yeast Mg(2+) channel Mrs2.
Acta Crystallogr.,Sect.D, 69, 2013
3RB3
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Dpo4 extension ternary complex with 3'-terminal primer A base opposite the 1-methylguanine (m1g) lesion
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
著者Rechkoblit, O, Patel, D.J.
登録日2011-03-28
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011
3RBD
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Dpo4 extension ternary complex with 3'-terminal primer C base opposite the 3-methylcytosine (m3c) lesion
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CALCIUM ION, ...
著者Rechkoblit, O, Patel, D.J.
登録日2011-03-29
公開日2011-06-15
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Implications for damage recognition during Dpo4-mediated mutagenic bypass of m1G and m3C lesions.
Structure, 19, 2011
5ORM
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BU of 5orm by Molmil
Crystal structure of designed cPPR-Telo1
分子名称: cPPR-Telo1
著者Spahr, H, Rackham, O.
登録日2017-08-16
公開日2018-06-20
実験手法X-RAY DIFFRACTION (2.08 Å)
主引用文献Modular ssDNA binding and inhibition of telomerase activity by designer PPR proteins.
Nat Commun, 9, 2018
3RON
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BU of 3ron by Molmil
Crystal Structure and Hemolytic Activity of the Cyt1Aa Toxin from Bacillus thuringiensis subsp. israelensis
分子名称: Type-1Aa cytolytic delta-endotoxin
著者Cohen, S, Albeck, S, Ben-Dov, E, Cahan, R, Firer, M, Zaritsky, A, Dym, O, Israel Structural Proteomics Center (ISPC)
登録日2011-04-26
公開日2011-10-12
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Cyt1Aa Toxin: Crystal Structure Reveals Implications for Its Membrane-Perforating Function.
J.Mol.Biol., 413, 2011
5OC0
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Structure of E. coli superoxide oxidase
分子名称: Cytochrome b561, GLYCEROL, MAGNESIUM ION, ...
著者Lundgren, C.A.K, Sjostrand, D, Biner, O, Bennett, M, von Ballmoos, C, Hogbom, M.
登録日2017-06-29
公開日2018-06-20
最終更新日2018-11-07
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Scavenging of superoxide by a membrane-bound superoxide oxidase.
Nat. Chem. Biol., 14, 2018
3NTY
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Crystal structure of AKR1C1 in complex with NADP and 5-Phenyl,3-chlorosalicylic acid
分子名称: 5-chloro-4-hydroxybiphenyl-3-carboxylic acid, Aldo-keto reductase family 1 member C1, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Dhagat, U, El-Kabbani, O.
登録日2010-07-06
公開日2011-04-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Probing the inhibitor selectivity pocket of human 20 alpha-hydroxysteroid dehydrogenase (AKR1C1) with X-ray crystallography and site-directed mutagenesis
Bioorg.Med.Chem.Lett., 21, 2011
5O2R
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Cryo-EM structure of the proline-rich antimicrobial peptide Api137 bound to the terminating ribosome
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Graf, M, Berninghausen, O, Beckmann, R, Wilson, D.N.
登録日2017-05-22
公開日2017-07-26
最終更新日2019-02-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献An antimicrobial peptide that inhibits translation by trapping release factors on the ribosome.
Nat. Struct. Mol. Biol., 24, 2017
5O6K
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Structure of Polyphosphate Kinase from Meiothermus ruber N121D
分子名称: DIPHOSPHATE, PHOSPHATE ION, Polyphosphate:AMP phosphotransferase
著者Kemper, F, Gerhardt, S, Einsle, O.
登録日2017-06-06
公開日2018-03-21
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.903 Å)
主引用文献Substrate recognition and mechanism revealed by ligand-bound polyphosphate kinase 2 structures.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5OC7
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BU of 5oc7 by Molmil
Crystal structure of the pleckstrin-homology domain of Bcr-Abl in complex with monobody Mb(Bcr-PH_4).
分子名称: Breakpoint cluster region protein,pleckstrin-homology domain of Bcr-Abl, D-MYO-INOSITOL-4,5-BISPHOSPHATE, GLYCEROL, ...
著者Reckel, S, Reynaud, A, Pojer, F, Hantschel, O.
登録日2017-06-29
公開日2017-12-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.652 Å)
主引用文献Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase.
Nat Commun, 8, 2017
5OEJ
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Structure of Tra1 subunit within the chromatin modifying complex SAGA
分子名称: Tra1 subunit within the chromatin modifying complex SAGA
著者Sharov, G, Voltz, K, Durand, A, Kolesnikova, O, Papai, G, Myasnikov, A.G, Dejaegere, A, Ben-Shem, A, Schultz, P.
登録日2017-07-07
公開日2017-08-02
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.7 Å)
主引用文献Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA.
Nat Commun, 8, 2017
5O1L
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Structure of Latex Clearing Protein LCP in the open state with bound imidazole
分子名称: (R,R)-2,3-BUTANEDIOL, 1,2-ETHANEDIOL, IMIDAZOLE, ...
著者Ilcu, L, Roether, W, Birke, J, Brausemann, A, Einsle, O, Jendrossek, D.
登録日2017-05-18
公開日2017-08-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Structural and Functional Analysis of Latex Clearing Protein (Lcp) Provides Insight into the Enzymatic Cleavage of Rubber.
Sci Rep, 7, 2017
5OAF
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Human Rvb1/Rvb2 heterohexamer in INO80 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2
著者Aramayo, R.J, Bythell-Douglas, R, Ayala, R, Willhoft, O, Wigley, D, Zhang, X.
登録日2017-06-21
公開日2017-12-13
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.06 Å)
主引用文献Cryo-EM structures of the human INO80 chromatin-remodeling complex.
Nat. Struct. Mol. Biol., 25, 2018
5OAR
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Crystal structure of native beta-N-acetylhexosaminidase isolated from Aspergillus oryzae
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL, ...
著者Skerlova, J, Rezacova, P, Brynda, J, Pachl, P, Otwinowski, Z, Vanek, O.
登録日2017-06-23
公開日2017-12-27
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of native beta-N-acetylhexosaminidase isolated from Aspergillus oryzae sheds light onto its substrate specificity, high stability, and regulation by propeptide.
FEBS J., 285, 2018

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件を2024-08-07に公開中

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