8PV3
| Chaetomium thermophilum pre-60S State 9 - pre-5S rotation - immature H68/H69 - composite structure | 分子名称: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | 登録日 | 2023-07-17 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023
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8PTW
| Chaetomium thermophilum Rix1-complex | 分子名称: | Pre-rRNA-processing protein IPI3, Pre-rRNA-processing protein RIX1 | 著者 | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | 登録日 | 2023-07-15 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023
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8PV7
| Chaetomium thermophilum pre-60S State 1 - pre-5S rotation (Arx1/Nog2 state) - Composite structure | 分子名称: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | 登録日 | 2023-07-17 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (2.12 Å) | 主引用文献 | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023
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8PMS
| NADase from Aspergillus fumigatus with replaced C-terminus from Neurospora crassa | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kallio, J.P, Ferrario, E, Stromland, O, Ziegler, M. | 登録日 | 2023-06-29 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Novel Calcium-Binding Motif Stabilizes and Increases the Activity of Aspergillus fumigatus Ecto-NADase. Biochemistry, 62, 2023
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8PV1
| Chaetomium thermophilum pre-60S State 6 - pre-5S rotation - L1 intermediate - composite structure | 分子名称: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | 登録日 | 2023-07-17 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (2.56 Å) | 主引用文献 | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023
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8PV4
| Chaetomium thermophilum pre-60S State 2 - pre-5S rotation with Rix1 complex - composite structure | 分子名称: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | 登録日 | 2023-07-17 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023
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8PMR
| NADase from Aspergillus fumigatus with mutated calcium binding motif (D219A/E220A) | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Kallio, J.P, Ferrario, E, Stromland, O, Ziegler, M. | 登録日 | 2023-06-29 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Novel Calcium-Binding Motif Stabilizes and Increases the Activity of Aspergillus fumigatus Ecto-NADase. Biochemistry, 62, 2023
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2VA6
| X-ray crystal structure of beta secretase complexed with compound 24 | 分子名称: | (6S)-2-amino-6-(3'-methoxybiphenyl-3-yl)-3,6-dimethyl-5,6-dihydropyrimidin-4(3H)-one, BETA SECRETASE 1, IODIDE ION | 著者 | Edwards, P.D, Albert, J.S, Sylvester, M, Aharony, D, Andisik, D, Callaghan, O, Campbell, J.B, Carr, R.A, Chessari, G, Congreve, M, Frederickson, M, Folmer, R.H.A, Geschwindner, S, Koether, G, Kolmodin, K, Krumrine, J, Mauger, R.C, Murray, C.W, Olsson, L.L, Patel, S, Spear, N, Tian, G. | 登録日 | 2007-08-30 | 公開日 | 2007-11-13 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Application of Fragment-Based Lead Generation to the Discovery of Novel, Cyclic Amidine Beta-Secretase Inhibitors with Nanomolar Potency, Cellular Activity, and High Ligand Efficiency. J.Med.Chem., 50, 2007
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8PV5
| Chaetomium thermophilum pre-60S State 8 - pre-5S rotation without Foot - composite structure | 分子名称: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | 登録日 | 2023-07-17 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (2.86 Å) | 主引用文献 | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023
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8PVA
| Structure of bacterial ribosome determined by cryoEM at 100 keV | 分子名称: | 16S rRNA, 23S rRNA, 50S ribosomal protein L14, ... | 著者 | McMullan, G, Naydenova, K, Mihaylov, D, Peet, M.J, Wilson, H, Yamashita, K, Dickerson, J.L, Chen, S, Cannone, G, Lee, Y, Hutchings, K.A, Gittins, O, Sobhy, M, Wells, T, El-Gomati, M.M, Dalby, J, Meffert, M, Schulze-Briese, C, Henderson, R, Russo, C.J. | 登録日 | 2023-07-17 | 公開日 | 2023-11-29 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Structure determination by cryoEM at 100 keV. Proc.Natl.Acad.Sci.USA, 120, 2023
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8PVG
| Structure of E. coli glutamine synthetase determined by cryoEM at 100 keV | 分子名称: | Glutamine synthetase | 著者 | McMullan, G, Naydenova, K, Mihaylov, D, Peet, M.J, Wilson, H, Yamashita, K, Dickerson, J.L, Chen, S, Cannone, G, Lee, Y, Hutchings, K.A, Gittins, O, Sobhy, M, Wells, T, El-Gomati, M.M, Dalby, J, Meffert, M, Schulze-Briese, C, Henderson, R, Russo, C.J. | 登録日 | 2023-07-17 | 公開日 | 2023-11-29 | 最終更新日 | 2023-12-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure determination by cryoEM at 100 keV. Proc.Natl.Acad.Sci.USA, 120, 2023
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8PV6
| Chaetomium thermophilum pre-60S State 3 - post-5S rotation with Rix1 complex with Foot - composite structure | 分子名称: | 26S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Thoms, M, Cheng, J, Denk, T, Berninghausen, O, Beckmann, R. | 登録日 | 2023-07-17 | 公開日 | 2023-11-15 | 最終更新日 | 2023-12-20 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Structural insights into coordinating 5S RNP rotation with ITS2 pre-RNA processing during ribosome formation. Embo Rep., 24, 2023
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2V8N
| Wild-type Structure of Lactose Permease | 分子名称: | LACTOSE PERMEASE | 著者 | Guan, L, Mirza, O, Verner, G, Iwata, S, Kaback, H.R. | 登録日 | 2007-08-09 | 公開日 | 2007-09-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Structural Determination of Wild-Type Lactose Permease. Proc.Natl.Acad.Sci.USA, 104, 2007
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8QPB
| Cryo-EM Structure of Pre-B+ATP Complex (core part) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | 登録日 | 2023-10-01 | 公開日 | 2024-05-22 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8QP9
| Cryo-EM Structure of Pre-B+AMPPNP Complex (core part) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Pre-mRNA-processing factor 6, ... | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | 登録日 | 2023-09-30 | 公開日 | 2024-05-22 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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8R08
| Cryo-EM structure of the cross-exon pre-B+AMPPNP complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ... | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | 登録日 | 2023-10-31 | 公開日 | 2024-05-22 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (6.1 Å) | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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4N3O
| 2.4 Angstrom Resolution Crystal Structure of Putative Sugar Kinase from Campylobacter jejuni. | 分子名称: | CALCIUM ION, Putative D-glycero-D-manno-heptose 7-phosphate kinase | 著者 | Minasov, G, Wawrzak, Z, Gordon, E, Onopriyenko, O, Grimshaw, S, Kwon, K, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2013-10-07 | 公開日 | 2013-10-16 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | 2.4 Angstrom Resolution Crystal Structure of Putative Sugar Kinase from Campylobacter jejuni. TO BE PUBLISHED
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8QPE
| Cryo-EM Structure of Pre-B-like Complex (core part) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Microfibrillar-associated protein 1, ... | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | 登録日 | 2023-10-01 | 公開日 | 2024-05-22 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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2V0R
| crystal structure of a hairpin exchange variant (LTx) of the targeting LINE-1 retrotransposon endonuclease | 分子名称: | LTX, SULFATE ION | 著者 | Repanas, K, Zingler, N, Layer, L.E, Schumann, G.G, Perrakis, A, Weichenrieder, O. | 登録日 | 2007-05-17 | 公開日 | 2007-07-17 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Determinants for DNA Target Structure Selectivity of the Human Line-1 Retrotransposon Endonuclease Nucleic Acids Res., 35, 2007
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8QZS
| Cryo-EM structure of the cross-exon B-like complex | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Microfibrillar-associated protein 1, NHP2-like protein 1, ... | 著者 | Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R. | 登録日 | 2023-10-29 | 公開日 | 2024-05-22 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insights into the cross-exon to cross-intron spliceosome switch. Nature, 630, 2024
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2V4H
| NEMO CC2-LZ domain - 1D5 DARPin complex | 分子名称: | 1D5 DARPIN, NF-KAPPA-B ESSENTIAL MODULATOR | 著者 | Grubisha, O, Duquerroy, S, Cordier, F, Haouz, A, Delepierre, M, Veron, M, Agou, F. | 登録日 | 2008-09-22 | 公開日 | 2009-11-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Darpin-Assisted Crystallography of the Cc2-Lz Domain of Nemo Reveals a Coupling between Dimerization and Ubiquitin-Binding. J.Mol.Biol., 395, 2010
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8R9W
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8R9Y
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5DXR
| Crystal Structure of the ER-alpha Ligand-binding Domain in Complex with the Cyclofenil Derivative 4,4'-{[(3R)-3-methylcyclohexylidene]methanediyl}diphenol | 分子名称: | 4,4'-{[(3R)-3-methylcyclohexylidene]methanediyl}diphenol, Estrogen receptor, Nuclear receptor coactivator 2 | 著者 | Nwachukwu, J.C, Srinivasan, S, Zheng, Y, Wang, S, Min, J, Dong, C, Liao, Z, Cavett, V, Nowak, J, Houtman, R, Carlson, K.E, Josan, J.S, Elemento, O, Katzenellenbogen, J.A, Zhou, H.B, Nettles, K.W. | 登録日 | 2015-09-23 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | 主引用文献 | Predictive features of ligand-specific signaling through the estrogen receptor. Mol.Syst.Biol., 12, 2016
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8R9Z
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