4RKM
 
 | | Wolinella succinogenes octaheme sulfite reductase MccA, form I | | Descriptor: | (R,R)-2,3-BUTANEDIOL, ACETATE ION, COPPER (I) ION, ... | | Authors: | Hermann, B, Kern, M, La Pietra, L, Simon, J, Einsle, O. | | Deposit date: | 2014-10-13 | | Release date: | 2015-02-04 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | The octahaem MccA is a haem c-copper sulfite reductase.
Nature, 520, 2015
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4RMG
 | | Human Sirt2 in complex with SirReal2 and NAD+ | | Descriptor: | 2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]-N-[5-(naphthalen-1-ylmethyl)-1,3-thiazol-2-yl]acetamide, NAD-dependent protein deacetylase sirtuin-2, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | | Authors: | Rumpf, T, Schiedel, M, Karaman, B, Roessler, C, North, B.J, Lehotzky, A, Olah, J, Ladwein, K.I, Schmidtkunz, K, Gajer, M, Pannek, M, Steegborn, C, Sinclair, D.A, Gerhardt, S, Ovadi, J, Schutkowski, M, Sippl, W, Einsle, O, Jung, M. | | Deposit date: | 2014-10-21 | | Release date: | 2015-02-25 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.88 Å) | | Cite: | Selective Sirt2 inhibition by ligand-induced rearrangement of the active site.
Nat Commun, 6, 2015
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1QWZ
 | | Crystal structure of Sortase B from S. aureus complexed with MTSET | | Descriptor: | 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, NICKEL (II) ION, NPQTN specific sortase B, ... | | Authors: | Zong, Y, Mazmanian, S.K, Schneewind, O, Narayana, S.V. | | Deposit date: | 2003-09-03 | | Release date: | 2004-04-06 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | The structure of sortase B, a cysteine transpeptidase that tethers surface protein to the Staphylococcus aureus cell wall
Structure, 12, 2004
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1QDB
 | | CYTOCHROME C NITRITE REDUCTASE | | Descriptor: | CALCIUM ION, CYTOCHROME C NITRITE REDUCTASE, HEME C, ... | | Authors: | Einsle, O, Messerschmidt, A, Stach, P, Huber, R, Kroneck, P.M.H. | | Deposit date: | 1999-05-19 | | Release date: | 1999-08-18 | | Last modified: | 2021-03-03 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structure of cytochrome c nitrite reductase.
Nature, 400, 1999
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4S2Z
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4TN9
 | | Crystal structure of Clostridium histolyticum ColG collagenase polycystic kidney disease-like domain at 1.4 Angstrom resolution | | Descriptor: | Collagenase | | Authors: | Bauer, R, Sakon, J, Philominathan, S.T.L, Matsushita, O, Gann, S. | | Deposit date: | 2014-06-03 | | Release date: | 2015-03-11 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structures of three polycystic kidney disease-like domains from Clostridium histolyticum collagenases ColG and ColH.
Acta Crystallogr.,Sect.D, 71, 2015
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1QJH
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7QBA
 | | CryoEM structure of the ABC transporter NosDFY complexed with nitrous oxide reductase NosZ | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, MAGNESIUM ION, ... | | Authors: | Zipfel, S, Mueller, C, Topitsch, A, Lutz, M, Zhang, L, Einsle, O. | | Deposit date: | 2021-11-18 | | Release date: | 2022-08-03 | | Last modified: | 2024-07-17 | | Method: | ELECTRON MICROSCOPY (3.78 Å) | | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase.
Nature, 608, 2022
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4S1A
 | | Crystal structure of a hypothetical protein Cthe_0052 from Ruminiclostridium thermocellum ATCC 27405 | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CITRATE ANION, TETRAETHYLENE GLYCOL, ... | | Authors: | Filippova, E.V, Wawrzak, Z, Minasov, G, Kiryukhina, O, Endres, M, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2015-01-09 | | Release date: | 2015-01-28 | | Last modified: | 2018-01-24 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Crystal structure of a hypothetical protein Cthe_0052 from Ruminiclostridium thermocellum ATCC27405
To be Published
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4S1W
 | | Structure of a putative Glutamine--Fructose-6-Phosphate Aminotransferase from Staphylococcus aureus subsp. aureus Mu50 | | Descriptor: | DI(HYDROXYETHYL)ETHER, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] | | Authors: | Filippova, E.V, Shuvalova, L, Kiryukhina, O, Jedrzejczak, R, Babnigg, G, Rubin, E, Sacchettini, J, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | | Deposit date: | 2015-01-15 | | Release date: | 2015-03-18 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | Structure of a putative Glutamine--Fructose-6-Phosphate Aminotransferase from Staphylococcus aureus subsp. aureus Mu50
To be Published
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4S34
 | | ERK2 (I84A) in complex with AMP-PNP | | Descriptor: | MAGNESIUM ION, Mitogen-activated protein kinase 1, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | Authors: | Livnah, O, Karamansha, Y, Tzarum, N. | | Deposit date: | 2015-01-26 | | Release date: | 2016-01-27 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Multiple mechanisms render Erk proteins MEK-independent
To be Published
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7QVM
 | | Human Oxytocin receptor (OTR) oxytocin Gq chimera (mGoqi) complex | | Descriptor: | Antibody fragment scFv16, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | Authors: | Waltenspuhl, Y, Ehrenmann, J, Vacca, S, Thom, C, Medalia, O, Pluckthun, A. | | Deposit date: | 2022-01-21 | | Release date: | 2022-08-10 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structural basis for the activation and ligand recognition of the human oxytocin receptor.
Nat Commun, 13, 2022
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4TQE
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1T2P
 | | Crystal structure of Sortase A from Staphylococcus aureus | | Descriptor: | sortase | | Authors: | Zong, Y, Bice, T.W, Ton-That, H, Schneewind, O, Narayana, S.V. | | Deposit date: | 2004-04-22 | | Release date: | 2004-09-07 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | CRYSTAL STRUCTURES OF STAPHYLOCOCCUS AUREUS SORTASE A AND ITS SUBSTRATE COMPLEX
J.Biol.Chem., 279, 2004
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4RKN
 | | Wolinella succinogenes octaheme sulfite reductase MccA, form II | | Descriptor: | COPPER (II) ION, DITHIONITE, MccA, ... | | Authors: | Hermann, B, Kern, M, La Pietra, L, Simon, J, Einsle, O. | | Deposit date: | 2014-10-13 | | Release date: | 2015-02-04 | | Last modified: | 2017-11-22 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | The octahaem MccA is a haem c-copper sulfite reductase.
Nature, 520, 2015
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1T6D
 | | MIRAS phasing of the Aquifex aeolicus Ppx/GppA phosphatase: crystal structure of the type II variant | | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, exopolyphosphatase | | Authors: | Kristensen, O, Laurberg, M, Liljas, A, Kastrup, J.S, Gajhede, M. | | Deposit date: | 2004-05-06 | | Release date: | 2004-08-03 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural characterization of the stringent response related exopolyphosphatase/guanosine pentaphosphate phosphohydrolase protein family
Biochemistry, 43, 2004
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4S32
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4S1D
 | | Structure of IgG1 Fab fragment in complex with Biotincytidinamide | | Descriptor: | MAB M33 FAB FRAGMENT, heavy chain, light chain, ... | | Authors: | Dengl, S, Hoffmann, E, Grote, M, Wagner, C, Mundigl, O, Georges, G, Theorey, I, Stubenrauch, K.-G, Bujotzek, A, Josel, H.-P, Dziadek, S, Benz, J, Brinkmann, U. | | Deposit date: | 2015-01-13 | | Release date: | 2015-03-04 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to antibodies.
Faseb J., 29, 2015
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4ROM
 | | Deoxyhemoglobin in complex with imidazolylacryloyl derivatives | | Descriptor: | 4-{2-chloro-4-[3-(1H-imidazol-2-yl)propanoyl]phenoxy}butanoic acid, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | | Authors: | Omar, A.M, Mahran, M.A, Ghatge, M.N, Chowdhury, N, Bamane, F.H.A, El-Araby, M.E, Abdulmalik, O, Safo, M.K. | | Deposit date: | 2014-10-28 | | Release date: | 2015-05-20 | | Last modified: | 2015-06-10 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Identification of a novel class of covalent modifiers of hemoglobin as potential antisickling agents.
Org.Biomol.Chem., 13, 2015
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4S30
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1S2T
 | | Crystal Structure Of Apo Phosphoenolpyruvate Mutase | | Descriptor: | Phosphoenolpyruvate phosphomutase | | Authors: | Liu, S, Lu, Z, Han, Y, Jia, Y, Howard, A, Dunaway-Mariano, D, Herzberg, O. | | Deposit date: | 2004-01-11 | | Release date: | 2004-05-04 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Conformational Flexibility of PEP Mutase
Biochemistry, 43, 2004
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4RYK
 | | Crystal structure of a putative transcriptional regulator from Listeria monocytogenes EGD-e | | Descriptor: | DI(HYDROXYETHYL)ETHER, L(+)-TARTARIC ACID, Lmo0325 protein, ... | | Authors: | Filippova, E.V, Wawrzak, Z, Minasov, G, Kiryukhina, O, Jedrzejczak, R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2014-12-15 | | Release date: | 2015-01-07 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.09 Å) | | Cite: | Crystal structure of a putative transcriptional regulator from Listeria monocytogenes EGD-e
To be Published
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4RTF
 | | Crystal structure of molecular chaperone DnaK from Mycobacterium tuberculosis H37Rv | | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Chaperone protein DnaK, TETRAETHYLENE GLYCOL | | Authors: | Filippova, E.V, Minasov, G, Kiryukhina, O, Endres, M, Babnigg, G, Rubin, E, Sacchettini, J, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG), Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors (MTBI) | | Deposit date: | 2014-11-14 | | Release date: | 2014-12-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.77 Å) | | Cite: | Crystal structure of molecular chaperone DnaK from Mycobacterium tuberculosis H37Rv
To be Published
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4RVR
 | | Crystal Structure of the bromodomain of human BAZ2B in complex WITH GSK2801 | | Descriptor: | 1,2-ETHANEDIOL, 1-{1-[2-(methylsulfonyl)phenyl]-7-propoxyindolizin-3-yl}ethanone, Bromodomain adjacent to zinc finger domain protein 2B | | Authors: | Chaikuad, A, Felletar, I, Chung, C.W, Drewry, D, Chen, P, Filippakopoulos, P, Fedorov, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2014-11-27 | | Release date: | 2014-12-10 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.98 Å) | | Cite: | Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.
J.Med.Chem., 59, 2016
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1S4W
 | | NMR structure of the cytoplasmic domain of integrin AIIb in DPC micelles | | Descriptor: | Integrin alpha-IIb | | Authors: | Vinogradova, O, Vaynberg, J, Kong, X, Haas, T.A, Plow, E.F, Qin, J. | | Deposit date: | 2004-01-19 | | Release date: | 2004-03-09 | | Last modified: | 2024-05-22 | | Method: | SOLUTION NMR | | Cite: | Membrane-mediated structural transitions at the cytoplasmic face during integrin activation.
Proc.Natl.Acad.Sci.USA, 101, 2004
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