2DVI
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![BU of 2dvi by Molmil](/molmil-images/mine/2dvi) | Complex structure of CCA-adding enzyme, mini-DCC and CTP | Descriptor: | CCA-adding enzyme, CYTIDINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Tomita, K, Ishitani, R, Fukai, S, Nureki, O. | Deposit date: | 2006-07-31 | Release date: | 2006-11-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.61 Å) | Cite: | Complete crystallographic analysis of the dynamics of CCA sequence addition Nature, 443, 2006
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2CSX
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![BU of 2csx by Molmil](/molmil-images/mine/2csx) | Crystal structure of Aquifex aeolicus methionyl-tRNA synthetase complexed with tRNA(Met) | Descriptor: | Methionyl-tRNA synthetase, RNA (75-MER) | Authors: | Nakanishi, K, Ogiso, Y, Nakama, T, Fukai, S, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-23 | Release date: | 2005-09-20 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for anticodon recognition by methionyl-tRNA synthetase. Nat.Struct.Mol.Biol., 12, 2005
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2DR9
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![BU of 2dr9 by Molmil](/molmil-images/mine/2dr9) | Complex structure of CCA-adding enzyme with tRNAminiDCC | Descriptor: | CCA-adding enzyme, SULFATE ION, tRNA (34-MER) | Authors: | Tomita, K, Ishitani, R, Fukai, S, Nureki, O. | Deposit date: | 2006-06-08 | Release date: | 2006-11-14 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Complete crystallographic analysis of the dynamics of CCA sequence addition Nature, 443, 2006
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1HZD
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![BU of 1hzd by Molmil](/molmil-images/mine/1hzd) | CRYSTAL STRUCTURE OF HUMAN AUH PROTEIN, AN RNA-BINDING HOMOLOGUE OF ENOYL-COA HYDRATASE | Descriptor: | AU-BINDING PROTEIN/ENOYL-COA HYDRATASE | Authors: | Kurimoto, K, Fukai, S, Nureki, O, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-01-24 | Release date: | 2001-12-12 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of human AUH protein, a single-stranded RNA binding homolog of enoyl-CoA hydratase. Structure, 9, 2001
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2DER
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![BU of 2der by Molmil](/molmil-images/mine/2der) | Cocrystal structure of an RNA sulfuration enzyme MnmA and tRNA-Glu in the initial tRNA binding state | Descriptor: | PHOSPHATE ION, SULFATE ION, tRNA, ... | Authors: | Numata, T, Ikeuchi, Y, Fukai, S, Suzuki, T, Nureki, O. | Deposit date: | 2006-02-17 | Release date: | 2006-08-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Snapshots of tRNA sulphuration via an adenylated intermediate Nature, 442, 2006
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2DET
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![BU of 2det by Molmil](/molmil-images/mine/2det) | Cocrystal structure of an RNA sulfuration enzyme MnmA and tRNA-Glu in the pre-reaction state | Descriptor: | SULFATE ION, tRNA, tRNA-specific 2-thiouridylase mnmA | Authors: | Numata, T, Ikeuchi, Y, Fukai, S, Suzuki, T, Nureki, O. | Deposit date: | 2006-02-17 | Release date: | 2006-08-15 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Snapshots of tRNA sulphuration via an adenylated intermediate Nature, 442, 2006
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2DEU
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![BU of 2deu by Molmil](/molmil-images/mine/2deu) | Cocrystal structure of an RNA sulfuration enzyme MnmA and tRNA-Glu in the adenylated intermediate state | Descriptor: | ADENOSINE MONOPHOSPHATE, SULFATE ION, tRNA, ... | Authors: | Numata, T, Ikeuchi, Y, Fukai, S, Suzuki, T, Nureki, O. | Deposit date: | 2006-02-17 | Release date: | 2006-08-15 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Snapshots of tRNA sulphuration via an adenylated intermediate Nature, 442, 2006
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1J1U
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![BU of 1j1u by Molmil](/molmil-images/mine/1j1u) | Crystal structure of archaeal tyrosyl-tRNA synthetase complexed with tRNA(Tyr) and L-tyrosine | Descriptor: | MAGNESIUM ION, TYROSINE, Tyrosyl-tRNA synthetase, ... | Authors: | Kobayashi, T, Nureki, O, Ishitani, R, Tukalo, M, Cusack, S, Sakamoto, K, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-12-17 | Release date: | 2003-06-03 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural basis for orthogonal tRNA specificities of tyrosyl-tRNA synthetases for genetic code expansion NAT.STRUCT.BIOL., 10, 2003
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1IUG
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![BU of 1iug by Molmil](/molmil-images/mine/1iug) | The crystal structure of aspartate aminotransferase which belongs to subgroup IV from Thermus thermophilus | Descriptor: | PHOSPHATE ION, putative aspartate aminotransferase | Authors: | Katsura, Y, Shirouzu, M, Yamaguchi, H, Ishitani, R, Nureki, O, Kuramitsu, S, Hayashi, H, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-03-04 | Release date: | 2003-11-25 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structure of a putative aspartate aminotransferase belonging to subgroup IV. Proteins, 55, 2004
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5X93
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![BU of 5x93 by Molmil](/molmil-images/mine/5x93) | Human endothelin receptor type-B in complex with antagonist K-8794 | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[6-[(4-tert-butylphenyl)sulfonylamino]-5-(2-methoxyphenoxy)-2-pyrimidin-2-yl-pyrimidin-4-yl]oxy-N-(2,6-dimethylphenyl)propanamide, CHOLESTEROL, ... | Authors: | Shihoya, W, Nishizawa, T, Yamashita, K, Hirata, K, Okuta, A, Tani, K, Fujiyoshi, Y, Doi, T, Nureki, O. | Deposit date: | 2017-03-05 | Release date: | 2017-08-16 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog Nat. Struct. Mol. Biol., 24, 2017
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1J1V
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![BU of 1j1v by Molmil](/molmil-images/mine/1j1v) | Crystal structure of DnaA domainIV complexed with DnaAbox DNA | Descriptor: | 5'-D(*CP*CP*TP*GP*TP*GP*GP*AP*TP*AP*AP*CP*A)-3', 5'-D(*TP*GP*TP*TP*AP*TP*CP*CP*AP*CP*AP*GP*G)-3', Chromosomal replication initiator protein dnaA | Authors: | Fujikawa, N, Kurumizaka, H, Nureki, O, Terada, T, Shirouzu, M, Katayama, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-12-18 | Release date: | 2003-04-22 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of replication origin recognition by the DnaA protein NUCLEIC ACIDS RES., 31, 2003
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1J3E
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![BU of 1j3e by Molmil](/molmil-images/mine/1j3e) | Crystal Structure of the E.coli SeqA protein complexed with N6-methyladenine- guanine mismatch DNA | Descriptor: | 5'-D(*AP*AP*GP*GP*(6MA)P*TP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*AP*GP*CP*CP*TP*T)-3', SeqA protein | Authors: | Fujikawa, N, Kurumizaka, H, Nureki, O, Tanaka, Y, Yamazoe, M, Hiraga, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-01-24 | Release date: | 2004-05-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural and biochemical analyses of hemimethylated DNA binding by the SeqA protein Nucleic Acids Res., 32, 2004
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1J2B
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![BU of 1j2b by Molmil](/molmil-images/mine/1j2b) | Crystal Structure Of Archaeosine tRNA-Guanine Transglycosylase Complexed With lambda-form tRNA(Val) | Descriptor: | Archaeosine tRNA-guanine transglycosylase, MAGNESIUM ION, ZINC ION, ... | Authors: | Ishitani, R, Nureki, O, Nameki, N, Okada, N, Nishimura, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-12-29 | Release date: | 2003-05-27 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Alternative Tertiary Structure of tRNA for Recognition by a Posttranscriptional Modification Enzyme Cell(Cambridge,Mass.), 113, 2003
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1IQ0
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![BU of 1iq0 by Molmil](/molmil-images/mine/1iq0) | THERMUS THERMOPHILUS ARGINYL-TRNA SYNTHETASE | Descriptor: | ARGINYL-TRNA SYNTHETASE | Authors: | Shimada, A, Nureki, O, Goto, M, Takahashi, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2001-05-24 | Release date: | 2001-11-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and mutational studies of the recognition of the arginine tRNA-specific major identity element, A20, by arginyl-tRNA synthetase. Proc.Natl.Acad.Sci.USA, 98, 2001
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6AEK
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![BU of 6aek by Molmil](/molmil-images/mine/6aek) | Crystal structure of ENPP1 in complex with pApG | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ... | Authors: | Kato, K, Nishimasu, H, Hirano, S, Hirano, H, Ishitani, R, Nureki, O. | Deposit date: | 2018-08-05 | Release date: | 2019-03-06 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1. Nat Commun, 9, 2018
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1IU3
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![BU of 1iu3 by Molmil](/molmil-images/mine/1iu3) | CRYSTAL STRUCTURE OF THE E.COLI SEQA PROTEIN COMPLEXED WITH HEMIMETHYLATED DNA | Descriptor: | 5'-D(*AP*AP*GP*GP*AP*TP*CP*CP*AP*A)-3', 5'-D(*TP*TP*GP*GP*AP*TP*CP*CP*TP*T)-3', SeqA protein | Authors: | Fujikawa, N, Kurumizaka, H, Nureki, O, Tanaka, Y, Yamazoe, M, Hiraga, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2002-02-26 | Release date: | 2003-06-17 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and biochemical analyses of hemimethylated DNA binding by the SeqA protein. Nucleic Acids Res., 32, 2004
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5XUZ
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![BU of 5xuz by Molmil](/molmil-images/mine/5xuz) | Crystal structure of Lachnospiraceae bacterium ND2006 Cpf1 in complex with crRNA and target DNA (CCCA PAM) | Descriptor: | 1,2-ETHANEDIOL, DNA (29-MER), DNA (5'-D(*CP*GP*TP*CP*CP*CP*CP*CP*A)-3'), ... | Authors: | Yamano, T, Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2017-06-26 | Release date: | 2017-08-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. Mol. Cell, 67, 2017
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5XW6
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![BU of 5xw6 by Molmil](/molmil-images/mine/5xw6) | Crystal structure of the chicken ATP-gated P2X7 receptor channel in the presence of competitive antagonist TNP-ATP at 3.1 Angstroms | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, P2X purinoceptor, SPIRO(2,4,6-TRINITROBENZENE[1,2A]-2O',3O'-METHYLENE-ADENINE-TRIPHOSPHATE | Authors: | Kasuya, G, Hattori, M, Nureki, O. | Deposit date: | 2017-06-29 | Release date: | 2017-10-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel Nat Commun, 8, 2017
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5Y78
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![BU of 5y78 by Molmil](/molmil-images/mine/5y78) | Crystal structure of the triose-phosphate/phosphate translocator in complex with inorganic phosphate | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, PHOSPHATE ION, Putative hexose phosphate translocator | Authors: | Lee, Y, Nishizawa, T, Takemoto, M, Kumazaki, K, Yamashita, K, Hirata, K, Minoda, A, Nagatoishi, S, Tsumoto, K, Ishitani, R, Nureki, O. | Deposit date: | 2017-08-16 | Release date: | 2017-10-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity Nat Plants, 3, 2017
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5Y79
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![BU of 5y79 by Molmil](/molmil-images/mine/5y79) | Crystal structure of the triose-phosphate/phosphate translocator in complex with 3-phosphoglycerate | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-PHOSPHOGLYCERIC ACID, CITRATE ANION, ... | Authors: | Lee, Y, Nishizawa, T, Takemoto, M, Kumazaki, K, Yamashita, K, Hirata, K, Minoda, A, Nagatoishi, S, Tsumoto, K, Ishitani, R, Nureki, O. | Deposit date: | 2017-08-16 | Release date: | 2017-10-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the triose-phosphate/phosphate translocator reveals the basis of substrate specificity Nat Plants, 3, 2017
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7EK2
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![BU of 7ek2 by Molmil](/molmil-images/mine/7ek2) | Cryo-EM structure of VCCN1 in lipid nanodisc | Descriptor: | Bestrophin-like protein | Authors: | Hagino, T, Kato, T, Kasuya, G, Kobayashi, K, Kusakizako, T, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2021-04-03 | Release date: | 2022-04-06 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structures of thylakoid-located voltage-dependent chloride channel VCCN1. Nat Commun, 13, 2022
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7EK1
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![BU of 7ek1 by Molmil](/molmil-images/mine/7ek1) | Cryo-EM structure of VCCN1 in detergent | Descriptor: | Bestrophin-like protein | Authors: | Hagino, T, Kato, T, Kasuya, G, Kobayashi, K, Kusakizako, T, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2021-04-03 | Release date: | 2022-04-06 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Cryo-EM structures of thylakoid-located voltage-dependent chloride channel VCCN1. Nat Commun, 13, 2022
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7EK3
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![BU of 7ek3 by Molmil](/molmil-images/mine/7ek3) | Cryo-EM structure of VCCN1 Y332A mutant in lipid nanodisc | Descriptor: | Bestrophin-like protein | Authors: | Hagino, T, Kato, T, Kasuya, G, Kobayashi, K, Kusakizako, T, Yamashita, K, Nishizawa, T, Nureki, O. | Deposit date: | 2021-04-03 | Release date: | 2022-04-06 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Cryo-EM structures of thylakoid-located voltage-dependent chloride channel VCCN1. Nat Commun, 13, 2022
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3WO7
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![BU of 3wo7 by Molmil](/molmil-images/mine/3wo7) | Crystal structure of YidC from Bacillus halodurans (form II) | Descriptor: | COPPER (II) ION, Membrane protein insertase YidC 2 | Authors: | Kumazaki, K, Tsukazaki, T, Ishitani, R, Nureki, O. | Deposit date: | 2013-12-20 | Release date: | 2014-04-23 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.201 Å) | Cite: | Structural basis of Sec-independent membrane protein insertion by YidC. Nature, 509, 2014
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3WVF
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![BU of 3wvf by Molmil](/molmil-images/mine/3wvf) | Crystal structure of YidC from Escherichia coli | Descriptor: | Membrane protein insertase YidC | Authors: | Kumazaki, K, Tsukazaki, T, Kishimoto, T, Ishitani, R, Nureki, O. | Deposit date: | 2014-05-20 | Release date: | 2014-12-17 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal structure of Escherichia coli YidC, a membrane protein chaperone and insertase Sci Rep, 4, 2014
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