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PDB: 98 results

1Q2J
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Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA
Descriptor: Mu-conotoxin SmIIIA
Authors:Keizer, D.W, West, P.J, Lee, E.F, Olivera, B.M, Bulaj, G, Yoshikami, D, Norton, R.S.
Deposit date:2003-07-24
Release date:2004-02-24
Last modified:2020-06-24
Method:SOLUTION NMR
Cite:Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA.
J.Biol.Chem., 278, 2003
1QFA
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STRUCTURE OF A NEUROPEPTIDE Y Y2 AGONIST
Descriptor: PROTEIN (NEUROPEPTIDE Y)
Authors:Barnham, K.J, Catalfamo, F, Pallaghy, P.K, Howlett, G.J, Norton, R.S.
Deposit date:1999-04-08
Release date:2000-04-08
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Helical structure and self-association in a 13 residue neuropeptide Y Y2 receptor agonist: relationship to biological activity.
Biochim.Biophys.Acta, 1435, 1999
1QBH
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SOLUTION STRUCTURE OF A BACULOVIRAL INHIBITOR OF APOPTOSIS (IAP) REPEAT
Descriptor: INHIBITOR OF APOPTOSIS PROTEIN (2MIHB/C-IAP-1), ZINC ION
Authors:Hinds, M.G, Norton, R.S, Vaux, D.L, Day, C.L.
Deposit date:1999-04-20
Release date:1999-10-20
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of a baculoviral inhibitor of apoptosis (IAP) repeat.
Nat.Struct.Biol., 6, 1999
1QDP
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SOLUTION STRUCTURE OF ROBUSTOXIN, THE LETHAL NEUROTOXIN FROM THE FUNNEL WEB SPIDER ATRAX ROBUSTUS, NMR, 20 STRUCTURES
Descriptor: ROBUSTOXIN
Authors:Pallaghy, P.K, Alewood, D, Alewood, P.F, Norton, R.S.
Deposit date:1997-10-09
Release date:1998-01-14
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Solution structure of robustoxin, the lethal neurotoxin from the funnel-web spider Atrax robustus.
FEBS Lett., 419, 1997
1S6W
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Solution Structure of hybrid white striped bass hepcidin
Descriptor: Hepcidin
Authors:Babon, J.J, Singh, S, Pennington, M.W, Norton, R.S, Westerman, M.E.
Deposit date:2004-01-28
Release date:2004-12-14
Last modified:2022-03-02
Method:SOLUTION NMR
Cite:Bass hepcidin synthesis, solution structure, antimicrobial activities and synergism, and in vivo hepatic response to bacterial infections.
J.Biol.Chem., 280, 2005
2JRY
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Structure and Sodium Channel Activity of an Excitatory I1-Superfamily Conotoxin
Descriptor: I-superfamily conotoxin r11a
Authors:Buczek, O, Wei, D, Babon, J, Yang, X, Fiedler, B, Chen, P, Yoshikami, D, Olivera, B, Bulaj, G, Norton, R.
Deposit date:2007-06-29
Release date:2007-10-23
Last modified:2022-03-09
Method:SOLUTION NMR
Cite:Structure and sodium channel activity of an excitatory I1-superfamily conotoxin.
Biochemistry, 46, 2007
2MTO
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Non-reducible analogues of alpha-conotoxin RgIA: [2,8]-cis dicarba RgIA
Descriptor: Alpha-conotoxin RgIA
Authors:Chhabra, S, Robinson, S, Norton, R.
Deposit date:2014-08-26
Release date:2014-11-26
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Dicarba Analogues of alpha-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets.
J.Med.Chem., 57, 2014
7KNN
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Solution structure of the alpha-conotoxin analogue [2-8]-alkyne Vc1.1
Descriptor: Alpha-conotoxin Vc1a
Authors:MacRaild, C.A, Robinson, S.D, Chhabra, S, Norton, R.S.
Deposit date:2020-11-05
Release date:2021-09-15
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Alkyne-Bridged alpha-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models.
J.Med.Chem., 64, 2021
2N8H
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Structural basis for the inhibition of voltage-gated sodium channels with conotoxin-muOxi-GVIIJ
Descriptor: conotoxin-muOxi-GVIIJ
Authors:Green, B.R, Chhabra, S, Norton, R.S.
Deposit date:2015-10-15
Release date:2016-02-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural Basis for the Inhibition of Voltage-gated Sodium Channels by Conotoxin mu O-GVIIJ.
J.Biol.Chem., 291, 2016
2JM2
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Structure of the N-terminal subdomain of insulin-like growth factor (IGF) binding protein-6 and its interactions with IGFs
Descriptor: Insulin-like growth factor-binding protein 6
Authors:Chandrashekaran, I.R, Yao, S, Wang, C.C, Bansal, P.S, Alewood, P.F, Forbes, B.E, Wallace, J.C, Bach, L.A, Norton, R.S.
Deposit date:2006-09-18
Release date:2007-03-27
Last modified:2023-12-20
Method:SOLUTION NMR
Cite:The N-Terminal Subdomain of Insulin-like Growth Factor (IGF) Binding Protein 6. Structure and Interaction with IGFs
Biochemistry, 46, 2007
2N34
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NMR assignments and solution structure of the JAK interaction region of SOCS5
Descriptor: Suppressor of cytokine signaling 5
Authors:Chandrashekaran, I.R, Mohanty, B, Linossi, E.M, Nicholson, S.E, Babon, J, Norton, R.S, Dagley, L.F, Leung, E.W.W, Murphy, J.M.
Deposit date:2015-05-21
Release date:2015-07-29
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure and Functional Characterization of the Conserved JAK Interaction Region in the Intrinsically Disordered N-Terminus of SOCS5.
Biochemistry, 54, 2015
2LXG
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NMR solution structure of Mu-conotoxin KIIIA
Descriptor: Mu-conotoxin KIIIA
Authors:Khoo, K.K, Norton, R.S.
Deposit date:2012-08-21
Release date:2013-02-06
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Distinct disulfide isomers of mu-conotoxins KIIIA and KIIIB block voltage-gated sodium channels.
Biochemistry, 51, 2012
2MG6
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Non-reducible analogues of alpha-conotoxin Vc1.1: [3,16]-trans dicarba Vc1.1
Descriptor: Alpha-conotoxin Vc1A
Authors:Robinson, S.D, Macraild, C.A, Van Lierop, B.J, Robinson, A.J, Norton, R.S.
Deposit date:2013-10-28
Release date:2013-12-18
Method:SOLUTION NMR
Cite:Dicarba alpha-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors.
Acs Chem.Biol., 8, 2013
2MFY
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Non-reducible analogues of alpha-conotoxin Vc1.1: [2,8]-trans dicarba Vc1.1
Descriptor: Alpha-conotoxin Vc1A
Authors:Robinson, S.D, Macraild, C.A, Van Lierop, B.J, Robinson, A.J, Norton, R.S.
Deposit date:2013-10-24
Release date:2013-12-18
Method:SOLUTION NMR
Cite:Dicarba alpha-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors.
Acs Chem.Biol., 8, 2013
2MFX
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Non-reducible analogues of alpha-conotoxin Vc1.1: [2,8]-cis dicarba Vc1.1
Descriptor: Alpha-conotoxin Vc1A
Authors:Robinson, S.D, Macraild, C.A, Van Lierop, B.J, Robinson, A.J, Norton, R.S.
Deposit date:2013-10-24
Release date:2013-12-18
Method:SOLUTION NMR
Cite:Dicarba alpha-conotoxin Vc1.1 analogues with differential selectivity for nicotinic acetylcholine and GABAB receptors.
Acs Chem.Biol., 8, 2013
2JTU
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NMR structure of iota-RXIA(38)
Descriptor: I-superfamily conotoxin r11a
Authors:Wei, D, Norton, R.
Deposit date:2007-08-06
Release date:2008-08-19
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:NMR structure of iota-RXIA(38)
To be Published
2JZ3
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SOCS box elonginBC ternary complex
Descriptor: Suppressor of cytokine signaling 3, Transcription elongation factor B polypeptide 1, Transcription elongation factor B polypeptide 2
Authors:Babon, J.J, Sabo, J, Soetopo, A, Yao, S, Bailey, M.F, Zhang, J, Nicola, N.A, Norton, R.S.
Deposit date:2007-12-27
Release date:2008-09-23
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The SOCS box domain of SOCS3: structure and interaction with the elonginBC-cullin5 ubiquitin ligase
J.Mol.Biol., 381, 2008
2K72
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Solution NMR structure of toxin-like potassium channel blocking domain in MMP23
Descriptor: Matrix metalloproteinase-23
Authors:Khoo, K.K, Feng, Z, Norton, R.S.
Deposit date:2008-07-31
Release date:2010-01-05
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Potassium channel modulation by a toxin domain in matrix metalloprotease 23.
J.Biol.Chem., 285, 2010
2LMZ
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Solution NMR structure of the novel conotoxin im23a from Conus imperialis
Descriptor: Conotoxin im17a
Authors:Khoo, K.K, Galea, C.A, Boonyalai, N, Norton, R.S.
Deposit date:2011-12-15
Release date:2012-03-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A helical conotoxin from Conus imperialis has a novel cysteine framework and defines a new superfamily.
J.Biol.Chem., 287, 2012
2L3O
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Solution structure of murine interleukin 3
Descriptor: Interleukin 3
Authors:Yao, S, Young, I.G, Norton, R.S, Murphy, J.M.
Deposit date:2010-09-20
Release date:2011-08-10
Method:SOLUTION NMR
Cite:Murine interleukin-3: structure, dynamics, and conformational heterogeneity in solution.
Biochemistry, 50, 2011
2N24
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Solution NMR structure of Contryphan-Vc1
Descriptor: O2_contryphan_Vc1
Authors:Robinson, S.D, Chhabra, S, Norton, R.S.
Deposit date:2015-04-27
Release date:2016-02-03
Last modified:2019-12-25
Method:SOLUTION NMR
Cite:A Naturally Occurring Peptide with an Elementary Single Disulfide-Directed beta-Hairpin Fold.
Structure, 24, 2016
2MTU
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Non-reducible analogues of alpha-conotoxin RgIA: [3,12]-trans dicarba RgIA
Descriptor: Dicarba Analogues of alpha-Conotoxin RgIA
Authors:Chhabra, S, Robinson, S.D, Norton, R.S.
Deposit date:2014-09-01
Release date:2014-11-26
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Dicarba Analogues of alpha-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets.
J.Med.Chem., 57, 2014
2MTT
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Non-reducible analogues of alpha-conotoxin RgIA: [3,12]-cis dicarba RgIA
Descriptor: Dicarba Analogues of alpha-Conotoxin RgIA
Authors:Chhabra, S, Robinson, S.D, Norton, R.S.
Deposit date:2014-08-31
Release date:2014-11-26
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Dicarba Analogues of alpha-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets.
J.Med.Chem., 57, 2014
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