2MTO

Non-reducible analogues of alpha-conotoxin RgIA: [2,8]-cis dicarba RgIA

Summary for 2MTO

• Entry DOI: 10.2210/pdb2mto/pdb
• Related: 2JUT
• NMR Information: BMRB: 25174
• Descriptor: Alpha-conotoxin RgIA (1 entity in total)
• Functional Keywords: dicarba, rgia, non-reducible, toxin
• Biological source: Conus regius (Crown cone)
• Cellular location: Secreted : P0C1D0
• Total number of polymer chains: 1
• Total formula weight: 1542.79

Authors

Chhabra, S.,Robinson, S.,Norton, R. (deposition date: 2014-08-26, release date: 2014-11-26, Last modification date: 2023-06-14)

• Primary citation: Chhabra, S.,Belgi, A.,Bartels, P.,van Lierop, B.J.,Robinson, S.D.,Kompella, S.N.,Hung, A.,Callaghan, B.P.,Adams, D.J.,Robinson, A.J.,Norton, R.S.; Dicarba Analogues of alpha-Conotoxin RgIA. Structure, Stability, and Activity at Potential Pain Targets.; J.Med.Chem., 57:9933-9944, 2014; PubMed: 25393758; DOI: 10.1021/jm501126u

Experimental method

SOLUTION NMR