2MCR

Solution structure of ShK-like immunomodulatory peptide from Brugia malayi (filarial worm)

Summary for 2MCR

• Entry DOI: 10.2210/pdb2mcr/pdb
• Related: 1ROO 2K72
• NMR Information: BMRB: 19450
• Descriptor: Probable zinc metalloproteinase, putative (1 entity in total)
• Functional Keywords: worms, bmk1, shk-like peptide, kv1.3, immune system
• Biological source: Brugia malayi
• Total number of polymer chains: 1
• Total formula weight: 4182.89

Authors

Chhabra, S.,Swarbrick, J.D.,Pennington, M.W.,Chang, S.C.,Norton, R.S. (deposition date: 2013-08-22, release date: 2014-07-02, Last modification date: 2023-06-14)

• Primary citation: Chhabra, S.,Chang, S.C.,Nguyen, H.M.,Huq, R.,Tanner, M.R.,Londono, L.M.,Estrada, R.,Dhawan, V.,Chauhan, S.,Upadhyay, S.K.,Gindin, M.,Hotez, P.J.,Valenzuela, J.G.,Mohanty, B.,Swarbrick, J.D.,Wulff, H.,Iadonato, S.P.,Gutman, G.A.,Beeton, C.,Pennington, M.W.,Norton, R.S.,Chandy, K.G.; Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases.; Faseb J., 28:3952-3964, 2014; PubMed: 24891519; DOI: 10.1096/fj.14-251967

Experimental method

SOLUTION NMR