1ITU
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![BU of 1itu by Molmil](/molmil-images/mine/1itu) | HUMAN RENAL DIPEPTIDASE COMPLEXED WITH CILASTATIN | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CILASTATIN, RENAL DIPEPTIDASE, ... | Authors: | Nitanai, Y, Satow, Y, Adachi, H, Tsujimoto, M. | Deposit date: | 2002-02-03 | Release date: | 2002-08-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Human Renal Dipeptidase Involved in beta-Lactam Hydrolysis J.Mol.Biol., 321, 2002
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1ITQ
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![BU of 1itq by Molmil](/molmil-images/mine/1itq) | HUMAN RENAL DIPEPTIDASE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, RENAL DIPEPTIDASE, ZINC ION | Authors: | Nitanai, Y, Satow, Y, Adachi, H, Tsujimoto, M. | Deposit date: | 2002-02-02 | Release date: | 2002-08-28 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of Human Renal Dipeptidase Involved in beta-Lactam Hydrolysis J.Mol.Biol., 321, 2002
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1FVM
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![BU of 1fvm by Molmil](/molmil-images/mine/1fvm) | Complex of vancomycin with DI-acetyl-LYS-D-ALA-D-ALA | Descriptor: | DI-ACETYL-LYS-D-ALA-D-ALA, VANCOMYCIN, vancosamine-(1-2)-beta-D-glucopyranose | Authors: | Nitanai, Y, Kakoi, K, Aoki, K. | Deposit date: | 2000-09-20 | Release date: | 2000-11-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal Structures of the Complexes between Vancomycin and Cell-Wall Precursor Analogs. J.Mol.Biol., 385, 2009
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2D3E
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![BU of 2d3e by Molmil](/molmil-images/mine/2d3e) | |
2ZQA
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![BU of 2zqa by Molmil](/molmil-images/mine/2zqa) | Cefotaxime acyl-intermediate structure of class a beta-lacta Toho-1 E166A/R274N/R276N triple mutant | Descriptor: | Beta-lactamase Toho-1, CEFOTAXIME, C3' cleaved, ... | Authors: | Nitanai, Y, Shimamura, T, Uchiyama, T, Ishii, Y, Takehira, M, Yutani, K, Matsuzawa, H, Miyano, M. | Deposit date: | 2008-08-07 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (0.95 Å) | Cite: | Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates To be Published
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2ZQD
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![BU of 2zqd by Molmil](/molmil-images/mine/2zqd) | Ceftazidime acyl-intermediate structure of class a beta-lact Toho-1 E166A/R274N/R276N triple mutant | Descriptor: | ACYLATED CEFTAZIDIME, Beta-lactamase Toho-1, SULFATE ION | Authors: | Nitanai, Y, Shimamura, T, Uchiyama, T, Ishii, Y, Takehira, M, Yutani, K, Matsuzawa, H, Miyano, M. | Deposit date: | 2008-08-07 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.19 Å) | Cite: | Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates To be Published
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2ZQ9
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![BU of 2zq9 by Molmil](/molmil-images/mine/2zq9) | Cephalothin acyl-intermediate structure of class a beta-lactamase Toho-1 E166A/R274N/R276N triple mutant | Descriptor: | 5-METHYLENE-2-[2-OXO-1-(2-THIOPHEN-2-YL-ACETYLAMINO)-ETHYL]-5,6-DIHYDRO-2H-[1,3]THIAZINE-4-CARBOXYLIC ACID, Beta-lactamase Toho-1, CEPHALOTHIN, ... | Authors: | Nitanai, Y, Shimamura, T, Uchiyama, T, Ishii, Y, Takehira, M, Yutani, K, Matsuzawa, H, Miyano, M. | Deposit date: | 2008-08-07 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.07 Å) | Cite: | Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates To be Published
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2ZQC
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![BU of 2zqc by Molmil](/molmil-images/mine/2zqc) | Aztreonam acyl-intermediate structure of class a beta-lactam Toho-1 E166A/R274N/R276N triple mutant | Descriptor: | 2-({[(1Z)-1-(2-amino-1,3-thiazol-4-yl)-2-oxo-2-{[(2S,3S)-1-oxo-3-(sulfoamino)butan-2-yl]amino}ethylidene]amino}oxy)-2-methylpropanoic acid, Beta-lactamase Toho-1, SULFATE ION | Authors: | Nitanai, Y, Shimamura, T, Uchiyama, T, Ishii, Y, Takehira, M, Yutani, K, Matsuzawa, H, Miyano, M. | Deposit date: | 2008-08-07 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.07 Å) | Cite: | Structural Basis of Extend Spectrum Beta-Lactamase in Correlation of Enzymatic Kinetics and Thermal Stability of Acyl-Intermediates To be Published
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3VPK
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![BU of 3vpk by Molmil](/molmil-images/mine/3vpk) | Crystal Structure of 6-Guanidinohexanoyl Trypsin | Descriptor: | 6-carbamimidamidohexanoic acid, CALCIUM ION, Cationic trypsin, ... | Authors: | Masuda, Y, Nitanai, Y, Mizutani, R, Noguchi, S. | Deposit date: | 2012-03-05 | Release date: | 2012-05-23 | Last modified: | 2013-02-06 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | Crystal structure of 6-guanidinohexanoyl trypsin near the optimum pH reveals the acyl-enzyme intermediate to be deacylated Proteins, 2012
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2EFS
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![BU of 2efs by Molmil](/molmil-images/mine/2efs) | Crystal structure of the C-terminal tropomyosin fragment with N- and C-terminal extensions of the leucine zipper at 2.0 angstroms resolution | Descriptor: | General control protein GCN4 and Tropomyosin 1 alpha chain | Authors: | Minakata, S, Nitanai, Y, Maeda, K, Oda, N, Wakabayashi, K, Maeda, Y. | Deposit date: | 2007-02-23 | Release date: | 2008-03-04 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Two crystal structures of tropomyosin C-terminal fragment 176-273: exposure of the hydrophobic core to the solvent destabilizes the tropomyosin molecule To be Published
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2EFR
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![BU of 2efr by Molmil](/molmil-images/mine/2efr) | Crystal structure of the c-terminal tropomyosin fragment with N- and C-terminal extensions of the leucine zipper at 1.8 angstroms resolution | Descriptor: | General control protein GCN4 and Tropomyosin 1 alpha chain | Authors: | Minakata, S, Nitanai, Y, Maeda, K, Oda, N, Wakabayashi, K, Maeda, Y. | Deposit date: | 2007-02-23 | Release date: | 2008-03-04 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Two crystal structures of tropomyosin C-terminal fragment 176-273: exposure of the hydrophobic core to the solvent destabilizes the tropomyosin molecule To be Published
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2ZGY
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![BU of 2zgy by Molmil](/molmil-images/mine/2zgy) | PARM with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Plasmid segregation protein parM | Authors: | Popp, D, Narita, A, Oda, T, Fujisawa, T, Matsuo, H, Nitanai, Y, Iwasa, M, Maeda, K, Onishi, H, Maeda, Y. | Deposit date: | 2008-01-30 | Release date: | 2008-02-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular structure of the ParM polymer and the mechanism leading to its nucleotide-driven dynamic instability Embo J., 27, 2008
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3AAA
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![BU of 3aaa by Molmil](/molmil-images/mine/3aaa) | Crystal Structure of Actin capping protein in complex with V-1 | Descriptor: | F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2, ISOPROPYL ALCOHOL, ... | Authors: | Takeda, S, Minakata, S, Narita, A, Kitazawa, M, Yamakuni, T, Maeda, Y, Nitanai, Y. | Deposit date: | 2009-11-12 | Release date: | 2010-08-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition Plos Biol., 8, 2010
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3AA7
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![BU of 3aa7 by Molmil](/molmil-images/mine/3aa7) | Crystal structure of Actin capping protein | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, BARIUM ION, F-actin-capping protein subunit alpha-1, ... | Authors: | Takeda, S, Minakata, S, Narita, A, Kitazawa, M, Yamakuni, T, Maeda, Y, Nitanai, Y. | Deposit date: | 2009-11-11 | Release date: | 2010-08-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition Plos Biol., 8, 2010
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3AAE
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![BU of 3aae by Molmil](/molmil-images/mine/3aae) | Crystal structure of Actin capping protein in complex with CARMIL fragment | Descriptor: | 32mer peptide from Leucine-rich repeat-containing protein 16A, F-actin-capping protein subunit alpha-1, F-actin-capping protein subunit beta isoforms 1 and 2 | Authors: | Takeda, S, Minakata, S, Narita, A, Kitazawa, M, Yamakuni, T, Maeda, Y, Nitanai, Y. | Deposit date: | 2009-11-16 | Release date: | 2010-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Two distinct mechanisms for the regulation of actin capping protein-competitive or allosteric inhibitions To be Published
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3AA0
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![BU of 3aa0 by Molmil](/molmil-images/mine/3aa0) | Crystal structure of Actin Capping Protein in complex with the Cp-binding motif derived from CARMIL | Descriptor: | 21mer peptide from Leucine-rich repeat-containing protein 16A, CARBONATE ION, F-actin-capping protein subunit alpha-1, ... | Authors: | Takeda, S, Minakata, S, Narita, A, Kitazawa, M, Yamakuni, T, Maeda, Y, Nitanai, Y. | Deposit date: | 2009-11-11 | Release date: | 2010-08-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition Plos Biol., 8, 2010
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3AA6
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![BU of 3aa6 by Molmil](/molmil-images/mine/3aa6) | Crystal structure of Actin capping protein in complex with the Cp-binding motif derived from CD2AP | Descriptor: | 23mer peptide from CD2-associated protein, BARIUM ION, F-actin-capping protein subunit alpha-1, ... | Authors: | Takeda, S, Minakata, S, Narita, A, Kitazawa, M, Yamakuni, T, Maeda, Y, Nitanai, Y. | Deposit date: | 2009-11-11 | Release date: | 2010-08-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition Plos Biol., 8, 2010
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2ZGZ
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![BU of 2zgz by Molmil](/molmil-images/mine/2zgz) | PARM with GMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plasmid segregation protein parM | Authors: | Popp, D, Narita, A, Oda, T, Fujisawa, T, Matsuo, H, Nitanai, Y, Iwasa, M, Maeda, K, Onishi, H, Maeda, Y. | Deposit date: | 2008-01-30 | Release date: | 2008-02-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Molecular structure of the ParM polymer and the mechanism leading to its nucleotide-driven dynamic instability Embo J., 27, 2008
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3AA1
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![BU of 3aa1 by Molmil](/molmil-images/mine/3aa1) | Crystal structure of Actin capping protein in complex with the Cp-binding motif derived from CKIP-1 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 23mer peptide from Pleckstrin homology domain-containing family O member 1, F-actin-capping protein subunit alpha-1, ... | Authors: | Takeda, S, Minakata, S, Narita, A, Kitazawa, M, Yamakuni, T, Maeda, Y, Nitanai, Y. | Deposit date: | 2009-11-11 | Release date: | 2010-08-04 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Two distinct mechanisms for actin capping protein regulation--steric and allosteric inhibition Plos Biol., 8, 2010
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2ZHC
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![BU of 2zhc by Molmil](/molmil-images/mine/2zhc) | ParM filament | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Plasmid segregation protein parM | Authors: | Popp, D, Narita, A, Oda, T, Fujisawa, T, Matsuo, H, Nitanai, Y, Iwasa, M, Maeda, K, Onishi, H, Maeda, Y. | Deposit date: | 2008-02-04 | Release date: | 2008-02-26 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (23 Å) | Cite: | Molecular structure of the ParM polymer and the mechanism leading to its nucleotide-driven dynamic instability Embo J., 27, 2008
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2ZQ8
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![BU of 2zq8 by Molmil](/molmil-images/mine/2zq8) | Apo structure of class a beta-lactamase Toho-1 R274N/R276N double mutant | Descriptor: | Beta-lactamase Toho-1, SULFATE ION | Authors: | Shimamura, T, Nitanai, Y, Uchiyama, T, Ago, H, Matsuzawa, H, Miyano, M. | Deposit date: | 2008-08-07 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.03 Å) | Cite: | Improvement of crystal quality by surface mutations of beta-lactamase Toho-1 Acta Crystallogr.,Sect.F, 65, 2009
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2ZQ7
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![BU of 2zq7 by Molmil](/molmil-images/mine/2zq7) | Apo structure of Class A beta-lactamase Toho-1 E166A/R274N/R276N triple mutant | Descriptor: | Beta-lactamase Toho-1, SULFATE ION | Authors: | Shimamura, T, Nitanai, Y, Uchiyama, T, Ago, H, Matsuzawa, H, Miyano, M. | Deposit date: | 2008-08-07 | Release date: | 2009-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (0.94 Å) | Cite: | Improvement of the Crystal Quality by the Surface Mutations on a Beta-Lactamase Toho-1 To be Published
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