Apo structure of class a beta-lactamase Toho-1 R274N/R276N double mutant

Summary for 2ZQ8

Related2ZQ7 2ZQ9 2ZQA 2ZQC 2ZQD
DescriptorBeta-lactamase Toho-1, SULFATE ION (3 entities in total)
Functional Keywordsextended-spectrum, esbl, beta-lactamase, toho-1, hydrolase, antibiotic resistance, plasmid
Biological sourceEscherichia coli
Total number of polymer chains1
Total molecular weight28656.1
Shimamura, T.,Nitanai, Y.,Uchiyama, T.,Ago, H.,Matsuzawa, H.,Miyano, M. (deposition date: 2008-08-07, release date: 2009-07-28, Last modification date: 2011-07-13)
Primary citation
Shimamura, T.,Nitanai, Y.,Uchiyama, T.,Matsuzawa, H.
Improvement of crystal quality by surface mutations of beta-lactamase Toho-1
Acta Crystallogr.,Sect.F, 65:379-382, 2009
PubMed: 19342785 (PDB entries with the same primary citation)
DOI: 10.1107/S1744309109008240
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.1494 0.4% 1.9% 5.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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PDB entries from 2020-10-21