7V74
| Thermostabilized human prestin in complex with sulfate | 分子名称: | 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine, CHOLESTEROL, SULFATE ION, ... | 著者 | Futamata, H, Fukuda, M, Yamashita, K, Nishizawa, T, Nureki, O. | 登録日 | 2021-08-21 | 公開日 | 2022-08-31 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.63 Å) | 主引用文献 | Cryo-EM structures of thermostabilized prestin provide mechanistic insights underlying outer hair cell electromotility. Nat Commun, 13, 2022
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7E8D
| NSD2 E1099K mutant bound to nucleosome | 分子名称: | DNA (185-MER), Histone H2A type 1, Histone H2B type 1-J, ... | 著者 | Sengoku, T, Sato, K, Nishizawa, T, Nureki, O, Ogata, K. | 登録日 | 2021-03-01 | 公開日 | 2021-11-10 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2. Nat Commun, 12, 2021
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7VVL
| PTH-bound human PTH1R in complex with Gs (class2) | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | 登録日 | 2021-11-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
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7VVN
| PTH-bound human PTH1R in complex with Gs (class4) | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | 登録日 | 2021-11-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
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7VVK
| PTH-bound human PTH1R in complex with Gs (class1) | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | 登録日 | 2021-11-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
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7VVM
| PTH-bound human PTH1R in complex with Gs (class3) | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | 登録日 | 2021-11-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
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7VVJ
| PTHrP-bound human PTH1R in complex with Gs | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | 登録日 | 2021-11-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
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7VVO
| PTH-bound human PTH1R in complex with Gs (class5) | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Kobayashi, K, Kusakizako, T, Miyauchi, H, Tomita, A, Kobayashi, K, Shihoya, W, Yamashita, K, Nishizawa, T, Kato, H.E, Nureki, O. | 登録日 | 2021-11-06 | 公開日 | 2022-08-03 | 最終更新日 | 2023-02-15 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Endogenous ligand recognition and structural transition of a human PTH receptor. Mol.Cell, 82, 2022
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7V94
| Cryo-EM structure of the Cas12c2-sgRNA-target DNA ternary complex | 分子名称: | Cas12c2, sgRNA, target DNA (non target strand), ... | 著者 | Kurihara, N, Hirano, H, Tomita, A, Kobayashi, K, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O. | 登録日 | 2021-08-24 | 公開日 | 2022-04-13 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | Structure of the type V-C CRISPR-Cas effector enzyme. Mol.Cell, 82, 2022
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7V93
| Cryo-EM structure of the Cas12c2-sgRNA binary complex | 分子名称: | cas12c2, sgRNA | 著者 | Kurihara, N, Hirano, H, Tomita, A, Kobayashi, K, Kusakizako, T, Nishizawa, T, Yamashita, K, Nishimasu, H, Nureki, O. | 登録日 | 2021-08-24 | 公開日 | 2022-04-13 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structure of the type V-C CRISPR-Cas effector enzyme. Mol.Cell, 82, 2022
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7V6B
| Structure of the Dicer-2-R2D2 heterodimer | 分子名称: | Dicer-2, isoform A, R2D2 | 著者 | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | 登録日 | 2021-08-20 | 公開日 | 2022-03-23 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex. Nature, 607, 2022
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7V6C
| Structure of the Dicer-2-R2D2 heterodimer bound to small RNA duplex | 分子名称: | Dicer-2, isoform A, R2D2, ... | 著者 | Yamaguchi, S, Nishizawa, T, Kusakizako, T, Yamashita, K, Tomita, A, Hirano, H, Nishimasu, H, Nureki, O. | 登録日 | 2021-08-20 | 公開日 | 2022-03-23 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex. Nature, 607, 2022
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7XHT
| Structure of the OgeuIscB-omega RNA-target DNA complex | 分子名称: | DNA (49-MER), DNA (5'-D(P*GP*AP*AP*GP*AP*AP*AP*AP*CP*CP*AP*T)-3'), LAURYL DIMETHYLAMINE-N-OXIDE, ... | 著者 | Kato, K, Okazaki, O, Isayama, Y, Ishikawa, J, Nishizawa, T, Nishimasu, H. | 登録日 | 2022-04-10 | 公開日 | 2022-12-14 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | 主引用文献 | Structure of the IscB-omega RNA ribonucleoprotein complex, the likely ancestor of CRISPR-Cas9. Nat Commun, 13, 2022
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7WAH
| Structure of Cas7-11 in complex with guide RNA and target RNA | 分子名称: | CRISPR-associated RAMP family protein, ZINC ION, crRNA (39-MER), ... | 著者 | Kato, K, Okazaki, S, Isayama, Y, Nishizawa, T, Nishimasu, H. | 登録日 | 2021-12-14 | 公開日 | 2022-06-15 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (2.45 Å) | 主引用文献 | Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex. Cell, 185, 2022
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7Y9Y
| Structure of the Cas7-11-Csx29-guide RNA-target RNA (no PFS) complex | 分子名称: | CHAT domain-containing protein, CRISPR-associated RAMP family protein, RNA (27-MER), ... | 著者 | Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. | 登録日 | 2022-06-26 | 公開日 | 2022-11-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease. Science, 378, 2022
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7Y9X
| Structure of the Cas7-11-Csx29-guide RNA complex | 分子名称: | CHAT domain-containing protein, CRISPR-associated RAMP family protein, ZINC ION, ... | 著者 | Kato, K, Okazaki, S, Ishikawa, J, Isayama, Y, Nishizawa, T, Nishimasu, H. | 登録日 | 2022-06-26 | 公開日 | 2022-11-09 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.49 Å) | 主引用文献 | RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease. Science, 378, 2022
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7F47
| Cryo-EM structure of Rhizobium etli MprF | 分子名称: | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, Hypothetical conserved protein, [(2R)-1-[[(2R)-3-[(2S)-2,6-bis(azanyl)hexanoyl]oxy-2-oxidanyl-propoxy]-oxidanyl-phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (E)-octadec-9-enoate | 著者 | Nishimura, M, Hirano, H, Kobayashi, K, Gill, C.P, Phan, C.N.K, Kise, Y, Kusakizako, T, Yamashita, K, Ito, Y, Roy, H, Nishizawa, T, Nureki, O. | 登録日 | 2021-06-17 | 公開日 | 2022-06-22 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | 主引用文献 | Cryo-EM structure of Rhizobium etli MprF To Be Published
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7EFD
| 1.77 A cryo-EM structure of Streptavidin using first 40 frames (corresponding to about 40 e/A^2 total dose) | 分子名称: | BIOTIN, Streptavidin | 著者 | Hiraizumi, M, Yamashita, K, Nishizawa, T, Kotecha, A, Nureki, O. | 登録日 | 2021-03-21 | 公開日 | 2021-04-28 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (1.77 Å) | 主引用文献 | 1.77 A cryo-EM structure of Streptavidin using first 40 frames (corresponding to about 40e/A^2 total dose) To Be Published
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7EFC
| 1.70 A cryo-EM structure of streptavidin | 分子名称: | BIOTIN, Streptavidin | 著者 | Hiraizumi, M, Yamashita, K, Nishizawa, T, Kotecha, A, Nureki, O. | 登録日 | 2021-03-21 | 公開日 | 2021-04-28 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (1.7 Å) | 主引用文献 | 1.70 A cryo-EM structure of streptavidin using all frames (corresponding to 70 e/A^2 total dose) To Be Published
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7DY0
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