1Z9D
 
 | | Crystal structure of a putative uridylate kinase (UMP-kinase) from Streptococcus pyogenes | | 分子名称: | SULFATE ION, uridylate kinase | | 著者 | Rajashankar, K.R, Kniewel, R, Lee, K, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2005-04-01 | | 公開日 | 2005-04-19 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of a putative uridylate kinase (UMP-kinase) from Streptococcus pyogenes
To be Published
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1LX7
 | | Structure of E. coli uridine phosphorylase at 2.0A | | 分子名称: | uridine phosphorylase | | 著者 | Burling, T, Buglino, J.A, Kniewel, R, Chadna, T, Beckwith, A, Lima, C.D, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | | 登録日 | 2002-06-04 | | 公開日 | 2002-06-12 | | 最終更新日 | 2021-02-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of Escherichia coli uridine phosphorylase at 2.0 A.
Acta Crystallogr.,Sect.D, 59, 2003
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1R5H
 | | Crystal Structure of MetAP2 complexed with A320282 | | 分子名称: | MANGANESE (II) ION, Methionine aminopeptidase 2, N'-(2S,3R)-3-AMINO-4-CYCLOHEXYL-2-HYDROXY-BUTANO-N-(4-METHYLPHENYL)HYDRAZIDE | | 著者 | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | | 登録日 | 2003-10-10 | | 公開日 | 2004-10-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg.Med.Chem.Lett., 14, 2004
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1R58
 | | Crystal Structure of MetAP2 complexed with A357300 | | 分子名称: | MANGANESE (II) ION, Methionine aminopeptidase 2, N'-((2S,3R)-3-AMINO-2-HYDROXY-5-(ISOPROPYLSULFANYL)PENTANOYL)-N-3-CHLOROBENZOYL HYDRAZIDE | | 著者 | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Ericken, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | | 登録日 | 2003-10-09 | | 公開日 | 2004-10-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg.Med.Chem.Lett., 14, 2004
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4CPZ
 | | Structure of the Neuraminidase from the B/Lyon/CHU/15.216/2011 virus in complex with Zanamivir | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Vachieri, S.G, Collins, P.J, Escuret, V, Casalegno, J.S, Cattle, N, Ferraris, O, Sabatier, M, Frobert, E, Caro, V, Skehel, J.J, Gamblin, S.J, Valla, F, Valette, M, Ottmann, M, McCauley, J.W, Daniels, R.S, Lina, B. | | 登録日 | 2014-02-09 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A Novel I221 L Substitution in Neuraminidase Confers High Level Resistance to Oseltamivir in Influenza B Viruses.
J.Infect.Dis., 210, 2014
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1DBI
 | | CRYSTAL STRUCTURE OF A THERMOSTABLE SERINE PROTEASE | | 分子名称: | AK.1 SERINE PROTEASE, CALCIUM ION, SODIUM ION | | 著者 | Smith, C.A, Toogood, H.S, Baker, H.M, Daniel, R.M, Baker, E.N. | | 登録日 | 1999-11-02 | | 公開日 | 1999-11-18 | | 最終更新日 | 2017-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Calcium-mediated thermostability in the subtilisin superfamily: the crystal structure of Bacillus Ak.1 protease at 1.8 A resolution.
J.Mol.Biol., 294, 1999
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4CPN
 | | Structure of the Neuraminidase from the B/Brisbane/60/2008 virus in complex with Zanamivir | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Vachieri, S.G, Collins, P.J, Escuret, V, Casalegno, J.S, Cattle, N, Ferraris, O, Sabatier, M, Frobert, E, Caro, V, Skehel, J.J, Gamblin, S.J, Valla, F, Valette, M, Ottmann, M, McCauley, J.W, Daniels, R.S, Lina, B. | | 登録日 | 2014-02-08 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | A Novel I221 L Substitution in Neuraminidase Confers High Level Resistance to Oseltamivir in Influenza B Viruses.
J.Infect.Dis., 210, 2014
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1R5G
 | | Crystal Structure of MetAP2 complexed with A311263 | | 分子名称: | (2S,3R)-3-AMINO-2-HYDROXY-5-(ETHYLSULFANYL)PENTANOYL-((S)-(-)-(1-NAPHTHYL)ETHYL)AMIDE, MANGANESE (II) ION, Methionine aminopeptidase 2 | | 著者 | Sheppard, G.S, Wang, J, Kawai, M, BaMaung, N.Y, Craig, R.A, Erickson, S.A, Lynch, L, Patel, J, Yang, F, Searle, X.B, Lou, P, Park, C, Kim, K.H, Henkin, J, Lesniewski, R. | | 登録日 | 2003-10-10 | | 公開日 | 2004-10-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | 3-Amino-2-hydroxyamides and related compounds as inhibitors of methionine aminopeptidase-2.
Bioorg.Med.Chem.Lett., 14, 2004
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4CPO
 | | Structure of the Neuraminidase from the B/Lyon/CHU/15.216/2011 virus | | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Vachieri, S.G, Collins, P.J, Escuret, V, Casalegno, J.S, Cattle, N, Ferraris, O, Sabatier, M, Frobert, E, Caro, V, Skehel, J.J, Gamblin, S.J, Valla, F, Valette, M, Ottmann, M, McCauley, J.W, Daniels, R.S, Lina, B. | | 登録日 | 2014-02-08 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | A Novel I221 L Substitution in Neuraminidase Confers High Level Resistance to Oseltamivir in Influenza B Viruses.
J.Infect.Dis., 210, 2014
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1RV0
 | | 1930 Swine H1 Hemagglutinin complexed with LSTA | | 分子名称: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-alpha-D-glucopyranose, hemagglutinin | | 著者 | Skehel, J.J, Gamblin, S.J, Haire, L.F, Russell, R.J, Stevens, D.J, Xiao, B, Ha, Y, Vasisht, N, Steinhauer, D.A, Daniels, R.S. | | 登録日 | 2003-12-12 | | 公開日 | 2004-03-30 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structure and receptor binding properties of the 1918 influenza hemagglutinin.
Science, 303, 2004
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4E58
 | | Crystal structure of GCC(LCG)CCGC duplex containing LNA residue | | 分子名称: | RNA duplex containing CCG repeats, SULFATE ION | | 著者 | Kiliszek, A, Kierzek, R, Krzyzosiak, W.J, Rypniewski, R. | | 登録日 | 2012-03-14 | | 公開日 | 2012-12-12 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.952 Å) | | 主引用文献 | Crystallographic characterization of CCG repeats.
Nucleic Acids Res., 40, 2012
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4CPM
 | | Structure of the Neuraminidase from the B/Brisbane/60/2008 virus in complex with Oseltamivir | | 分子名称: | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Vachieri, S.G, Collins, P.J, Escuret, V, Casalegno, J.S, Cattle, N, Ferraris, O, Sabatier, M, Frobert, E, Caro, V, Skehel, J.J, Gamblin, S.J, Valla, F, Valette, M, Ottmann, M, McCauley, J.W, Daniels, R.S, Lina, B. | | 登録日 | 2014-02-07 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | A Novel I221 L Substitution in Neuraminidase Confers High Level Resistance to Oseltamivir in Influenza B Viruses.
J.Infect.Dis., 210, 2014
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1XP5
 | | Structure Of The (Sr)Ca2+-ATPase E2-AlF4- Form | | 分子名称: | MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | | 著者 | Olesen, C, Sorensen, T.L.S, Nielsen, R.C, Moller, J.V, Nissen, P. | | 登録日 | 2004-10-08 | | 公開日 | 2005-01-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Dephosphorylation of the Calcium Pump Coupled to Counterion Occlusion
Science, 306, 2004
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4PF5
 | | Crystal structure of Concanavalin A complexed with a synthetic derivative of high-mannose chain | | 分子名称: | 1,2-ETHANEDIOL, 4-(hydroxymethyl)-1-(alpha-D-mannopyranosyl)-1H-1,2,3-triazole, Concanavalin-A, ... | | 著者 | Lafite, P, Daniellou, R. | | 登録日 | 2014-04-28 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Synthesis of High-Mannose Oligosaccharide Analogues through Click Chemistry: True Functional Mimics of Their Natural Counterparts Against Lectins?
Chemistry, 21, 2015
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2C77
 | | EF-Tu complexed with a GTP analog and the antibiotic GE2270 A | | 分子名称: | DI(HYDROXYETHYL)ETHER, ELONGATION FACTOR TU-B, MAGNESIUM ION, ... | | 著者 | Parmeggiani, A, Krab, I.M, Okamura, S, Nielsen, R.C, Nyborg, J, Nissen, P. | | 登録日 | 2005-11-18 | | 公開日 | 2006-03-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
Biochemistry, 45, 2006
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5O81
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5O7Z
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2C78
 | | EF-Tu complexed with a GTP analog and the antibiotic pulvomycin | | 分子名称: | (1S,2S,3E,5E,7E,10S,11S,12S)-12-[(2R,4E,6E,8Z,10R,12E,14E,16Z,18S,19Z)-10,18-DIHYDROXY-12,16,19-TRIMETHYL-11,22-DIOXOOX ACYCLODOCOSA-4,6,8,12,14,16,19-HEPTAEN-2-YL]-2,11-DIHYDROXY-1,10-DIMETHYL-9-OXOTRIDECA-3,5,7-TRIEN-1-YL 6-DEOXY-2,4-DI-O-METHYL-BETA-L-GALACTOPYRANOSIDE, ELONGATION FACTOR TU-A, MAGNESIUM ION, ... | | 著者 | Parmeggiani, A, Krab, I.M, Okamura, S, Nielsen, R.C, Nyborg, J, Nissen, P. | | 登録日 | 2005-11-18 | | 公開日 | 2006-03-16 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu.
Biochemistry, 45, 2006
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1EO8
 | | INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY (HEAVY CHAIN), ... | | 著者 | Fleury, D, Gigant, B, Daniels, R.S, Skehel, J.J, Knossow, M, Bizebard, T. | | 登録日 | 2000-03-22 | | 公開日 | 2000-04-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural evidence for recognition of a single epitope by two distinct antibodies.
Proteins, 40, 2000
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4OUE
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4CPL
 | | Structure of the Neuraminidase from the B/Brisbane/60/2008 virus. | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Vachieri, S.G, Collins, P.J, Escuret, V, Casalegno, J.S, Cattle, N, Ferraris, O, Sabatier, M, Frobert, E, Caro, V, Skehel, J.J, Gamblin, S.J, Valla, F, Valette, M, Ottmann, M, McCauley, J.W, Daniels, R.S, Lina, B. | | 登録日 | 2014-02-07 | | 公開日 | 2014-05-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Novel I221 L Substitution in Neuraminidase Confers High Level Resistance to Oseltamivir in Influenza B Viruses.
J.Infect.Dis., 210, 2014
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2BVN
 | | E. coli EF-Tu:GDPNP in complex with the antibiotic enacyloxin IIa | | 分子名称: | ELONGATION FACTOR TU, ENACYLOXIN IIA, MAGNESIUM ION, ... | | 著者 | Parmeggiani, A, Krab, I.M, Watanabe, T, Nielsen, R.C, Dahlberg, C, Nyborg, J, Nissen, P. | | 登録日 | 2005-06-30 | | 公開日 | 2005-09-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Enacyloxin Iia Pinpoints a Binding Pocket of Elongation Factor TU for Development of Novel Antibiotics.
J.Biol.Chem., 281, 2006
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1QFU
 | | INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, PROTEIN (HEMAGGLUTININ (HA1 CHAIN)), ... | | 著者 | Fleury, D, Gigant, B, Bizebard, T, Daniels, R.S, Skehel, J.J, Knossow, M. | | 登録日 | 1999-04-14 | | 公開日 | 1999-04-16 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site.
Nat.Struct.Biol., 6, 1999
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1QZC
 | | Coordinates of S12, SH44, LH69 and SRL separately fitted into the cryo-EM map of EF-Tu ternary complex (GDP.Kirromycin) bound 70S ribosome | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S12 | | 著者 | Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. | | 登録日 | 2003-09-16 | | 公開日 | 2003-11-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy
Nat.Struct.Biol., 10, 2003
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1QZB
 | | Coordinates of the A-site tRNA model fitted into the cryo-EM map of 70S ribosome in the pre-translocational state | | 分子名称: | Phe-tRNA | | 著者 | Valle, M, Zavialov, A, Li, W, Stagg, S.M, Sengupta, J, Nielsen, R.C, Nissen, P, Harvey, S.C, Ehrenberg, M, Frank, J. | | 登録日 | 2003-09-16 | | 公開日 | 2003-11-04 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Incorporation of Aminoacyl-tRNA into the Ribosome as seen by Cryo-electron Microscopy
Nat.Struct.Biol., 10, 2003
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