2JIF
| Structure of human short-branched chain acyl-CoA dehydrogenase (ACADSB) | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A PERSULFIDE, ... | 著者 | Pike, A.C.W, Hozjan, V, Smee, C, Niesen, F.H, Kavanagh, K.L, Umeano, C, Turnbull, A.P, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C.H, Sundstrom, M, Oppermann, U. | 登録日 | 2007-02-28 | 公開日 | 2007-04-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of Human Short-Branched Chain Acyl-Coa Dehydrogenase To be Published
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2IW2
| Crystal structure of human Prolidase | 分子名称: | SODIUM ION, XAA-PRO DIPEPTIDASE | 著者 | Mueller, U, Niesen, F.H, Roske, Y, Goetz, F, Behlke, J, Buessow, K, Heinemann, U. | 登録日 | 2006-06-24 | 公開日 | 2006-07-05 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Crystal Structure of Human Prolidase: The Molecular Basis of Pd Disease To be Published
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1CF2
| THREE-DIMENSIONAL STRUCTURE OF D-GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM THE HYPERTHERMOPHILIC ARCHAEON METHANOTHERMUS FERVIDUS | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PROTEIN (GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE), SULFATE ION | 著者 | Charron, C, Talfournier, F, Isuppov, M.N, Branlant, G, Littlechild, J.A, Vitoux, B, Aubry, A. | 登録日 | 1999-03-24 | 公開日 | 2000-03-29 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystallization and preliminary X-ray diffraction studies of D-glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic archaeon Methanothermus fervidus. Acta Crystallogr.,Sect.D, 55, 1999
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2OKN
| Crystal Strcture of Human Prolidase | 分子名称: | HYDROGENPHOSPHATE ION, MANGANESE (II) ION, Xaa-Pro dipeptidase | 著者 | Mueller, U, Niesen, F.H, Roske, Y, Goetz, F, Behlke, J, Buessow, K, Heinemann, U, Protein Structure Factory (PSF) | 登録日 | 2007-01-17 | 公開日 | 2007-02-20 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Crystal Structure of Human Prolidase: The Molecular Basis of PD Disease. To be Published
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2GF0
| The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state | 分子名称: | GTP-binding protein Di-Ras1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Turnbull, A.P, Papagrigoriou, E, Yang, X, Schoch, G, Elkins, J, Gileadi, O, Salah, E, Bray, J, Wen-Hwa, L, Fedorov, O, Niesen, F.E, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC) | 登録日 | 2006-03-21 | 公開日 | 2006-04-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | The crystal structure of the human DiRas1 GTPase in the inactive GDP bound state To be Published
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2PQ5
| Crystal structure of Dual specificity protein phosphatase 13 (DUSP13) | 分子名称: | Dual specificity protein phosphatase 13 | 著者 | Ugochukwu, E, Salah, E, Savitsky, P, Barr, A, Pantic, N, Niesen, F, Burgess-Brown, N, Berridge, G, Bunkoczi, G, Uppenberg, J, Pike, A.C.W, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, von Delft, F, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2007-05-01 | 公開日 | 2007-05-22 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of Dual specificity protein phosphatase 13 (DUSP13). To be Published
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2X1H
| Crystal structure of the human MGC45594 gene product in complex with raloxifene | 分子名称: | 1,2-ETHANEDIOL, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2, ... | 著者 | Shafqat, N, Yue, W.W, Pike, A.C.W, Niesen, F, Ugochukwu, E, Krojer, T, Chaikuad, A, Smee, C, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | 登録日 | 2009-12-24 | 公開日 | 2010-11-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal Structure of the Human Mgc45594 Gene Product in Complex with Raloxifene To be Published
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2BT2
| Structure of the regulator of G-protein signaling 16 | 分子名称: | REGULATOR OF G-PROTEIN SIGNALING 16 | 著者 | Bunkoczi, G, Haroniti, A, Longman, E, Niesen, F, Soundararajan, M, Ball, L.J, von Delft, F, Doyle, D.A, Arrowsmith, C, Edwards, A, Sundstrom, M. | 登録日 | 2005-05-25 | 公開日 | 2005-06-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Diversity in the Rgs Domain and its Interaction with Heterotrimeric G Protein Alpha- Subunits. Proc.Natl.Acad.Sci.USA, 105, 2008
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1SAW
| X-ray structure of homo sapiens protein FLJ36880 | 分子名称: | CHLORIDE ION, MAGNESIUM ION, hypothetical protein FLJ36880 | 著者 | Manjasetty, B.A, Niesen, F.H, Delbrueck, H, Goetz, F, Sievert, V, Buessow, K, Behlke, J, Heinemann, U. | 登録日 | 2004-02-09 | 公開日 | 2004-10-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | X-ray structure of fumarylacetoacetate hydrolase family member Homo sapiens FLJ36880. Biol.Chem., 385, 2004
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2P8U
| Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I | 分子名称: | COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ... | 著者 | Turnbull, A, Shafqat, N, Salah, E, Niesen, F.H, Burgess, N, Bunkoczi, G, Debreczeni, J, Pike, A.C.W, Umeano, C, Gorrec, F, von Delft, F, Weigelt, J, Arrowsmith, C.H, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | 登録日 | 2007-03-23 | 公開日 | 2007-04-03 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design. J.Mol.Biol., 398, 2010
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2UYY
| Structure of the cytokine-like nuclear factor n-pac | 分子名称: | N-PAC PROTEIN, POTASSIUM ION, [(2R,3R,4R,5R)-5-(6-AMINO-9H-PURIN-9-YL)-3-HYDROXY-4-(PHOSPHONOOXY)TETRAHYDROFURAN-2-YL]METHYL [(2R,3S,4S)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL]METHYL DIHYDROGEN DIPHOSPHATE | 著者 | Tickle, J, Pilka, E.S, Bunkoczi, G, Berridge, G, Smee, C, Kavanagh, K.L, Hozjan, V, Niesen, F.H, Papagrigoriou, E, Pike, A.C.W, Turnbull, A, Arrowsmith, C.H, Edwards, A, Sundstrom, M, Weigelt, J, von Delft, F, Oppermann, U. | 登録日 | 2007-04-20 | 公開日 | 2007-07-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The Structure of the Cytokine-Like Nuclear Factor N-Pac To be Published
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2V3Q
| Serendipitous discovery and X-ray structure of a human phosphate binding apolipoprotein | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, HUMAN PHOSPHATE BINDING PROTEIN, ... | 著者 | Morales, R, Berna, A, Carpentier, P, Elias, M, Contreras-Martel, C, Renault, F, Nicodeme, M, Chesne-Seck, M.-L, Bernier, F, Dupuy, J, Schaeffer, C, Diemer, H, Van Dorsselaer, A, Fontecilla, J.C, Masson, P, Rochu, D, Chabriere, E. | 登録日 | 2007-06-20 | 公開日 | 2008-07-22 | 最終更新日 | 2016-01-27 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Tandem Use of X-Ray Crystallography and Mass Spectrometry to Obtain Ab Initio the Complete and Exact Amino Acids Sequence of Hpbp, a Human 38kDa Apolipoprotein Proteins: Struct., Funct., Bioinf., 71, 2008
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2X7H
| Crystal structure of the human MGC45594 gene product in complex with fenoprofen | 分子名称: | 1,2-ETHANEDIOL, FENOPROFEN, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... | 著者 | Shafqat, N, Yue, W.W, Ugochukwu, E, Niesen, F, Vollmar, M, Chaikuad, A, Pike, A.C.W, von Delft, F, Smee, C, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | 登録日 | 2010-02-26 | 公開日 | 2010-12-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal Structure of the Human Mgc45594 Gene Product in Complex with Fenoprofen To be Published
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2ES0
| Structure of the regulator of G-protein signaling domain of RGS6 | 分子名称: | regulator of G-protein signalling 6 | 著者 | Schoch, G.A, Phillips, C, Turnbull, A, Niesen, F, Johansson, C, Elkins, J.M, Longman, E, Gilealdi, C, Sobott, F, Ball, L, Sundstrom, M, Edwards, A, Arrowsmith, C, von Delft, F, Doyle, D.A, Structural Genomics Consortium (SGC) | 登録日 | 2005-10-25 | 公開日 | 2005-11-29 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits. Proc.Natl.Acad.Sci.Usa, 105, 2008
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2NZL
| Crystal structure of human hydroxyacid oxidase 1 | 分子名称: | FLAVIN MONONUCLEOTIDE, GLYOXYLIC ACID, Hydroxyacid oxidase 1 | 著者 | Ugochukwu, E, Kavanagh, K, Pilka, E, Berridge, G, Debreczeni, J.E, Papagrigoriou, E, Turnbull, A, Niesen, F, Gileadi, O, von Delft, F, Sundstrom, M, Arrowsmith, C.H, Weigelt, J, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC) | 登録日 | 2006-11-24 | 公開日 | 2006-12-12 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal structure of human hydroxyacid oxidase 1 To be Published
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1JYQ
| Xray Structure of Grb2 SH2 Domain Complexed with a Highly Affine Phospho Peptide | 分子名称: | GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, mAZ-pY-(alpha Me)pY-N-NH2 peptide inhibitor | 著者 | Nioche, P, Liu, W.-Q, Broutin, I, Charbonnier, F, Latreille, M.-T, Vidal, M, Roques, B, Garbay, C, Ducruix, A. | 登録日 | 2001-09-13 | 公開日 | 2002-03-13 | 最終更新日 | 2018-04-04 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor. J.Mol.Biol., 315, 2002
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1U2H
| X-ray Structure of the N-terminally truncated human APEP-1 | 分子名称: | Aortic preferentially expressed protein 1 | 著者 | Manjasetty, B.A, Scheich, C, Roske, Y, Niesen, F.H, Gotz, F, Bussow, K, Heinemann, U. | 登録日 | 2004-07-19 | 公開日 | 2005-07-05 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | 主引用文献 | X-ray structure of engineered human Aortic Preferentially Expressed Protein-1 (APEG-1) Bmc Struct.Biol., 5, 2005
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2VD5
| Structure of Human Myotonic Dystrophy Protein Kinase in Complex with the Bisindoylmaleide inhibitor BIM VIII | 分子名称: | 3-[1-(3-AMINOPROPYL)-1H-INDOL-3-YL]-4-(1-METHYL-1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, DMPK PROTEIN | 著者 | Pike, A.C.W, Amos, A, Elkins, J, Bullock, A, Guo, K, Fedorov, O, Bunkoczi, G, Filippakopoulos, P, Pilka, E.S, Ugochukwu, E, Umeano, C, Niesen, F, Sundstrom, M, Weigelt, J, Edwards, A, Arrowsmith, C.H, von Delft, F, Knapp, S. | 登録日 | 2007-09-30 | 公開日 | 2007-11-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structure of Dystrophia Myotonica Protein Kinase. Protein Sci., 18, 2009
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2GJT
| Crystal structure of the human receptor phosphatase PTPRO | 分子名称: | CHLORIDE ION, Receptor-type tyrosine-protein phosphatase PTPRO | 著者 | Barr, A, Ugochukwu, E, Eswaran, J, Das, S, Niesen, F, Savitsky, P, Turnbull, A, Sundstrom, M, Arrowsmith, C, Edwards, A, Weigelt, J, von Delft, F, Papagrigoriou, E, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2006-03-31 | 公開日 | 2006-05-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Large-scale structural analysis of the classical human protein tyrosine phosphatome. Cell(Cambridge,Mass.), 136, 2009
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3BHH
| Crystal structure of human calcium/calmodulin-dependent protein kinase IIB isoform 1 (CAMK2B) | 分子名称: | Calcium/calmodulin-dependent protein kinase type II beta chain, [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-6-(methylamino)pyrimidin-2-yl}amino)phenyl]acetonitrile | 著者 | Filippakopoulos, P, Rellos, P, Niesen, F, Burgess, N, Bullock, A, Berridge, G, Pike, A.C.W, Ugochukwu, E, Pilka, E.S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2007-11-28 | 公開日 | 2007-12-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure of Human Calcium/Calmodulin-Dependent Protein Kinase IIB Isoform 1 (CAMK2B). To be Published
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2BBW
| Crystal structure of human adenylate kinase 4 (AK4) in complex with diguanosine pentaphosphate | 分子名称: | DIGUANOSINE-PENTAPHOSPHATE, adenylate kinase 4, AK4 | 著者 | Filippakopoulos, P, Turnbull, A.P, Fedorov, O, Weigelt, J, Bunkoczi, G, Ugochukwu, E, Debreczeni, J, Niesen, F, von Delft, F, Edwards, A, Arrowsmith, C, Sundstrom, M, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2005-10-17 | 公開日 | 2005-12-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Crystal structure of human adenylate kinase 4 (AK4) in complex with diguanosine pentaphosphate To be Published
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2WM3
| Crystal structure of NmrA-like family domain containing protein 1 in complex with niflumic acid | 分子名称: | 2-{[3-(TRIFLUOROMETHYL)PHENYL]AMINO}NICOTINIC ACID, CHLORIDE ION, GLYCEROL, ... | 著者 | Bhatia, C, Yue, W.W, Niesen, F, Pilka, E, Ugochukwu, E, Savitsky, P, Hozjan, V, Roos, A.K, Filippakopoulos, P, von Delft, F, Heightman, T, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U. | 登録日 | 2009-06-29 | 公開日 | 2009-08-04 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of Nmra-Like Family Domain Containing Protein 1 in Complex with Niflumic Acid To be Published
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3BQR
| Crystal structure of human death associated protein kinase 3 (DAPK3) in complex with an imidazo-pyridazine ligand | 分子名称: | 4-(6-{[(1R)-1-(hydroxymethyl)propyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzoic acid, Death-associated protein kinase 3, GLYCEROL, ... | 著者 | Filippakopoulos, P, Rellos, P, Fedorov, O, Niesen, F, Pike, A.C.W, Pilka, E.S, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2007-12-20 | 公開日 | 2008-02-26 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Crystal Structure of Human Death Associated Protein Kinase 3 (DAPK3) in Complex with an Imidazo-Pyridazine Ligand. To be Published
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2ERX
| Crystal Structure of DiRas2 in Complex With GDP and Inorganic Phosphate | 分子名称: | GTP-binding protein Di-Ras2, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Papagrigoriou, E, Yang, X, Elkins, J, Niesen, F.E, Burgess, N, Salah, E, Fedorov, O, Ball, L.J, von Delft, F, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, Doyle, D. | 登録日 | 2005-10-25 | 公開日 | 2005-11-01 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal Structure of DiRas2 To be Published
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2ID2
| GAPN T244S mutant X-ray structure at 2.5 A | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NADP-dependent glyceraldehyde-3-phosphate dehydrogenase, SULFATE ION | 著者 | Pailot, A, D'Ambrosio, K, Corbier, C, Talfournier, F, Branlant, G. | 登録日 | 2006-09-14 | 公開日 | 2007-09-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Invariant Thr(244) is essential for the efficient acylation step of the non-phosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans. Biochem.J., 400, 2006
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