1DLG
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![BU of 1dlg by Molmil](/molmil-images/mine/1dlg) | CRYSTAL STRUCTURE OF THE C115S ENTEROBACTER CLOACAE MURA IN THE UN-LIGANDED STATE | Descriptor: | CYCLOHEXYLAMMONIUM ION, PHOSPHATE ION, UDP-N-ACETYLGLUCOSAMINE ENOLPYRUVYL TRANSFERASE MURA | Authors: | Schonbrunn, E, Eschenburg, S, Krekel, F, Luger, K, Amrhein, N. | Deposit date: | 1999-12-09 | Release date: | 2000-04-12 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Role of the loop containing residue 115 in the induced-fit mechanism of the bacterial cell wall biosynthetic enzyme MurA. Biochemistry, 39, 2000
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6N8V
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![BU of 6n8v by Molmil](/molmil-images/mine/6n8v) | Hsp104DWB open conformation | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Heat shock protein 104 | Authors: | Lee, S, Rho, S.H, Lee, J, Sung, N, Liu, J, Tsai, F.T.F. | Deposit date: | 2018-11-30 | Release date: | 2019-01-02 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (9.3 Å) | Cite: | Cryo-EM Structures of the Hsp104 Protein Disaggregase Captured in the ATP Conformation. Cell Rep, 26, 2019
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1DOA
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![BU of 1doa by Molmil](/molmil-images/mine/1doa) | Structure of the rho family gtp-binding protein cdc42 in complex with the multifunctional regulator rhogdi | Descriptor: | GERAN-8-YL GERAN, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Hoffman, G.R, Nassar, N, Cerione, R.C. | Deposit date: | 1999-12-20 | Release date: | 2000-02-09 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the Rho family GTP-binding protein Cdc42 in complex with the multifunctional regulator RhoGDI. Cell(Cambridge,Mass.), 100, 2000
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2WE0
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![BU of 2we0 by Molmil](/molmil-images/mine/2we0) | EBV dUTPase mutant Cys4Ser | Descriptor: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE, MALATE LIKE INTERMEDIATE, ... | Authors: | Freeman, L, Buisson, M, Tarbouriech, N, Burmeister, W.P. | Deposit date: | 2009-03-27 | Release date: | 2009-07-07 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | The Flexible Motif V of Epstein-Barr Virus Deoxyuridine 5'-Triphosphate Pyrophosphatase is Essential for Catalysis. J.Biol.Chem., 284, 2009
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1DVJ
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![BU of 1dvj by Molmil](/molmil-images/mine/1dvj) | CRYSTAL STRUCTURE OF OROTIDINE MONOPHOSPHATE DECARBOXYLASE COMPLEXED WITH 6-AZAUMP | Descriptor: | 6-AZA URIDINE 5'-MONOPHOSPHATE, OROTIDINE 5'-PHOSPHATE DECARBOXYLASE | Authors: | Wu, N, Mo, Y, Gao, J, Pai, E.F. | Deposit date: | 2000-03-30 | Release date: | 2000-04-05 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Electrostatic stress in catalysis: structure and mechanism of the enzyme orotidine monophosphate decarboxylase. Proc.Natl.Acad.Sci.USA, 97, 2000
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1E26
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![BU of 1e26 by Molmil](/molmil-images/mine/1e26) | Design, Synthesis and X-ray Crystal Structure of a Potent Dual Inhibitor of Thymidylate Synthase and Dihydrofolate Reductase as an Antitumor Agent. | Descriptor: | DIHYDROFOLATE REDUCTASE, N-[4-[2-(2-AMINO-4-METHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYL]GLUTAMIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Gangjee, A, Yu, J, McGuire, J.J, Cody, V, Galitsky, N, Kisliuk, R.L, Queener, S.F. | Deposit date: | 2000-05-17 | Release date: | 2001-05-17 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Ligand-Induced Conformational Changes in the Crystal Structures of Pneumocystis Carinii Dihydrofolate Reductase Complexes with Folate and Nadp+ Biochemistry, 38, 1999
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4CVD
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![BU of 4cvd by Molmil](/molmil-images/mine/4cvd) | |
6O22
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![BU of 6o22 by Molmil](/molmil-images/mine/6o22) | Structure of Asf1-H3:H4-Rtt109-Vps75 histone chaperone-lysine acetyltransferase complex with the histone substrate. | Descriptor: | Histone H3.2, Histone H4, Histone acetyltransferase RTT109, ... | Authors: | Danilenko, N, Carlomagno, T, Kirkpatrick, J.P. | Deposit date: | 2019-02-22 | Release date: | 2019-07-31 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR, SOLUTION SCATTERING | Cite: | Histone chaperone exploits intrinsic disorder to switch acetylation specificity. Nat Commun, 10, 2019
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6NZ6
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![BU of 6nz6 by Molmil](/molmil-images/mine/6nz6) | YcjX-GDP (type II) | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, YcjX Stress Protein | Authors: | Tsai, J, Sung, N, Lee, J, Chang, C, Lee, S, Tsai, F.T. | Deposit date: | 2019-02-12 | Release date: | 2019-09-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal Structure of the YcjX Stress Protein Reveals a Ras-Like GTP-Binding Protein. J.Mol.Biol., 431, 2019
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1DR0
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![BU of 1dr0 by Molmil](/molmil-images/mine/1dr0) | STRUCTURE OF MODIFIED 3-ISOPROPYLMALATE DEHYDROGENASE AT THE C-TERMINUS, HD708 | Descriptor: | 3-ISOPROPYLMALATE DEHYDROGENASE | Authors: | Nurachman, Z, Akanuma, S, Sato, T, Oshima, T, Tanaka, N. | Deposit date: | 2000-01-06 | Release date: | 2000-01-19 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Crystal structures of 3-isopropylmalate dehydrogenases with mutations at the C-terminus: crystallographic analyses of structure-stability relationships. Protein Eng., 13, 2000
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1DV7
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6NY1
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![BU of 6ny1 by Molmil](/molmil-images/mine/6ny1) | CasX-gRNA-DNA(30bp) State II | Descriptor: | CasX, DNA Non-target strand, DNA target strand, ... | Authors: | Liu, J.J, Orlova, N, Nogales, E, Doudna, J.A. | Deposit date: | 2019-02-10 | Release date: | 2019-02-27 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | CasX enzymes comprise a distinct family of RNA-guided genome editors. Nature, 566, 2019
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1E2E
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![BU of 1e2e by Molmil](/molmil-images/mine/1e2e) | Human thymidylate kinase complexed with thymidine monophosphate, adenosine diphosphate,a magnesium-ion and ALf3 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Ostermann, N, Schlichting, I, Brundiers, R, Konrad, M, Reinstein, J, Veit, T, Goody, R.S, Lavie, A. | Deposit date: | 2000-05-22 | Release date: | 2001-05-17 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Insights Into the Phosphoryltransfer Mechanism of Human Thymidylate Kinase Gained from Crystal Structures of Enzyme Complexes Along the Reaction Coordinate Structure, 8, 2000
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6NZ5
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![BU of 6nz5 by Molmil](/molmil-images/mine/6nz5) | YcjX-GDPCP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER, YcjX Stress Protein | Authors: | Lee, S, Tsai, J, Tsai, F.T, Sung, N, Lee, J, Chang, C. | Deposit date: | 2019-02-12 | Release date: | 2019-09-18 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.233 Å) | Cite: | Crystal Structure of the YcjX Stress Protein Reveals a Ras-Like GTP-Binding Protein. J.Mol.Biol., 431, 2019
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1DSY
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![BU of 1dsy by Molmil](/molmil-images/mine/1dsy) | C2 DOMAIN FROM PROTEIN KINASE C (ALPHA) COMPLEXED WITH CA2+ AND PHOSPHATIDYLSERINE | Descriptor: | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, CALCIUM ION, PHOSPHATE ION, ... | Authors: | Verdaguer, N, Corbalan-Garcia, S, Ochoa, W.F, Fita, I, Gomez-Fernandez, J.C. | Deposit date: | 2000-01-10 | Release date: | 2000-01-26 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine. EMBO J., 18, 1999
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6KDI
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![BU of 6kdi by Molmil](/molmil-images/mine/6kdi) | Antibody 64M-5 Fab including isoAsp in complex with dT(6-4)T | Descriptor: | Anti-(6-4) photoproduct antibody 64M-5 Fab (heavy chain), Anti-(6-4) photoproduct antibody 64M-5 Fab (light chain), DNA (5'-D(*(64T)P*(5PY))-3') | Authors: | Yokoyama, H, Mizutani, R, Noguchi, S, Hayashida, N. | Deposit date: | 2019-07-02 | Release date: | 2019-12-18 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and biochemical basis of the formation of isoaspartate in the complementarity-determining region of antibody 64M-5 Fab. Sci Rep, 9, 2019
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1DUF
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![BU of 1duf by Molmil](/molmil-images/mine/1duf) | THE NMR STRUCTURE OF DNA DODECAMER DETERMINED IN AQUEOUS DILUTE LIQUID CRYSTALLINE PHASE | Descriptor: | DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3') | Authors: | Tjandra, N, Tate, S, Ono, A, Kainosho, M, Bax, A. | Deposit date: | 2000-01-17 | Release date: | 2000-07-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The NMR Structure of a DNA Dodecamer in an Aqueous Dilute Liquid Crystalline Phase J.Am.Chem.Soc., 122, 2000
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5Z5F
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![BU of 5z5f by Molmil](/molmil-images/mine/5z5f) | Crystal structure of a thermostable glycoside hydrolase family 43 {beta}-1,4-xylosidase from Geobacillus thermoleovorans IT-08 in complex with L-arabinose | Descriptor: | Beta-xylosidase, CALCIUM ION, beta-L-arabinofuranose | Authors: | Rohman, A, van Oosterwijk, N, Puspaningsih, N.N.T, Dijkstra, B.W. | Deposit date: | 2018-01-18 | Release date: | 2018-04-25 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural basis of product inhibition by arabinose and xylose of the thermostable GH43 beta-1,4-xylosidase from Geobacillus thermoleovorans IT-08. PLoS ONE, 13, 2018
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2RSI
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![BU of 2rsi by Molmil](/molmil-images/mine/2rsi) | |
2RSC
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6O0C
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![BU of 6o0c by Molmil](/molmil-images/mine/6o0c) | NMR ensemble of computationally designed protein XAA_GVDQ mutant M4L | Descriptor: | Design construct XAA_GVDQ mutant M4L | Authors: | Wei, K.Y, Moschidi, D, Nerli, S, Sgourakis, N, Baker, D. | Deposit date: | 2019-02-15 | Release date: | 2020-04-22 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Computational design of closely related proteins that adopt two well-defined but structurally divergent folds. Proc.Natl.Acad.Sci.USA, 117, 2020
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6NUG
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![BU of 6nug by Molmil](/molmil-images/mine/6nug) | hGRNA4-28_3s | Descriptor: | Granulin-4 | Authors: | Dastpeyman, M, Bansal, P, Wilson, D, Loukas, A, Smout, M, Daly, N. | Deposit date: | 2019-02-01 | Release date: | 2020-02-05 | Last modified: | 2023-06-14 | Method: | SOLUTION NMR | Cite: | hGRN4-28_3s to be published
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6O6O
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![BU of 6o6o by Molmil](/molmil-images/mine/6o6o) | Structure of the regulator FasR from Mycobacterium tuberculosis | Descriptor: | MYRISTIC ACID, TetR family transcriptional regulator | Authors: | Larrieux, N, Trajtenberg, F, Lara, J, Gramajo, H, Buschiazzo, A. | Deposit date: | 2019-03-07 | Release date: | 2020-03-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine. Nat Commun, 11, 2020
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6O6T
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![BU of 6o6t by Molmil](/molmil-images/mine/6o6t) | Crystal structure of Csm6 H132A mutant | Descriptor: | Csm6 | Authors: | Jia, N, Patel, D.J. | Deposit date: | 2019-03-07 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.31 Å) | Cite: | CRISPR-Cas III-A Csm6 CARF Domain Is a Ring Nuclease Triggering Stepwise cA4Cleavage with ApA>p Formation Terminating RNase Activity. Mol.Cell, 75, 2019
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6O75
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![BU of 6o75 by Molmil](/molmil-images/mine/6o75) | Crystal structure of Csm1-Csm4 cassette in complex with pppApA | Descriptor: | CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A), Csm4, MANGANESE (II) ION, ... | Authors: | Jia, N, Patel, D.J. | Deposit date: | 2019-03-07 | Release date: | 2019-07-31 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Second Messenger cA4Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path. Mol.Cell, 75, 2019
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