8TAJ
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![BU of 8taj by Molmil](/molmil-images/mine/8taj) | Sequence specific (AATT) orientation of netropsin molecules at a unique minor groove binding site (position1) within a self-assembled 3D DNA lattice (4x6) | Descriptor: | CACODYLATE ION, DNA (5'-D(*GP*AP*GP*AP*AP*TP*TP*CP*CP*TP*GP*AP*CP*GP*GP*AP*AP*CP*TP*CP*A)-3'), DNA (5'-D(*TP*CP*TP*GP*AP*GP*TP*T)-3'), ... | Authors: | Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H. | Deposit date: | 2023-06-27 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Site-Specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-Assembled Three-Dimensional DNA Crystals. J.Am.Chem.Soc., 145, 2023
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8TC6
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![BU of 8tc6 by Molmil](/molmil-images/mine/8tc6) | Sequence specific (AATT and TGTCA) orientation of netropsin and ImPyPy molecules at two unique minor groove binding sites within a self-assembled 3D DNA lattice (4x5) | Descriptor: | CACODYLATE ION, DNA (5'-D(*GP*AP*GP*CP*AP*GP*AP*CP*CP*TP*GP*AP*CP*GP*AP*TP*GP*TP*CP*AP*C*(NT))-3'), DNA (5'-D(*TP*CP*GP*TP*GP*AP*CP*AP*T)-3'), ... | Authors: | Simmons, C.R, MacCulloch, T, Stephanopoulos, N, Yan, H. | Deposit date: | 2023-06-29 | Release date: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Site-Specific Arrangement and Structure Determination of Minor Groove Binding Molecules in Self-Assembled Three-Dimensional DNA Crystals. J.Am.Chem.Soc., 145, 2023
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6G1J
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![BU of 6g1j by Molmil](/molmil-images/mine/6g1j) | Phosphotriesterase PTE_C23M_1 | Descriptor: | 1-ethyl-1-methyl-cyclohexane, FORMIC ACID, GLYCEROL, ... | Authors: | Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. | Deposit date: | 2018-03-21 | Release date: | 2019-04-10 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Phosphotriesterase
PTE_C23M_1 To Be Published
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6G1T
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![BU of 6g1t by Molmil](/molmil-images/mine/6g1t) | TraN, a repressor of an Enterococcus conjugative type IV secretion system | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AM32, DNA (34-MER) | Authors: | Goessweiner-Mohr, N, Kohler, V, Keller, W. | Deposit date: | 2018-03-22 | Release date: | 2018-07-25 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | TraN: A novel repressor of an Enterococcus conjugative type IV secretion system. Nucleic Acids Res., 46, 2018
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4Y9H
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![BU of 4y9h by Molmil](/molmil-images/mine/4y9h) | The 1.43 angstrom crystal structure of bacteriorhodopsin crystallized from bicelles | Descriptor: | Bacteriorhodopsin, DECANE, DODECANE, ... | Authors: | Saiki, H, Sugiyama, S, Kakinouchi, K, Kawatake, S, Hanashima, S, Matsumori, N, Murata, M. | Deposit date: | 2015-02-17 | Release date: | 2016-02-17 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.43 Å) | Cite: | The 1.43 angstrom crystal structure of bacteriorhodopsin crystallized from bicelles To Be Published
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1XY3
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![BU of 1xy3 by Molmil](/molmil-images/mine/1xy3) | Urate oxidase from aspergillus flavus complexed with guanine | Descriptor: | GUANINE, Uricase | Authors: | Retailleau, P, Colloc'h, N, Vivares, D, Bonnete, F, Castro, B, El Hajji, M, Prange, T. | Deposit date: | 2004-11-09 | Release date: | 2005-03-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Urate oxidase from Aspergillus flavus: new crystal-packing contacts in relation to the content of the active site. Acta Crystallogr.,Sect.D, 61, 2005
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4YC2
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![BU of 4yc2 by Molmil](/molmil-images/mine/4yc2) | |
7PQQ
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![BU of 7pqq by Molmil](/molmil-images/mine/7pqq) | |
6GBU
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![BU of 6gbu by Molmil](/molmil-images/mine/6gbu) | Crystal structure of the second SH3 domain of FCHSD2 (SH3-2) in complex with the fourth SH3 domain of ITSN1 (SH3d) | Descriptor: | F-BAR and double SH3 domains protein 2, Intersectin-1 | Authors: | Almeida-Souza, L, Frank, R, Garcia-Nafria, J, Colussi, A, Gunawardana, N, Johnson, C.M, Yu, M, Howard, G, Andrews, B, Vallis, Y, McMahon, H.T. | Deposit date: | 2018-04-16 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.44 Å) | Cite: | A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits. Cell, 174, 2018
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4YBL
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![BU of 4ybl by Molmil](/molmil-images/mine/4ybl) | |
7PQG
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![BU of 7pqg by Molmil](/molmil-images/mine/7pqg) | |
6FWE
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![BU of 6fwe by Molmil](/molmil-images/mine/6fwe) | Phosphotriesterase PTE_C23_6 | Descriptor: | 1-[methoxy(methyl)phosphoryl]oxyethane, 1-ethyl-1-methyl-cyclohexane, FORMIC ACID, ... | Authors: | Dym, O, Aggarwal, N, Albeck, S, Unger, T, Hamer Rogotner, S, Silman, I, Leader, H, Ashani, Y, Goldsmith, M, Greisen, P, Tawfik, D, Sussman, L.J. | Deposit date: | 2018-03-06 | Release date: | 2019-03-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.774 Å) | Cite: | Phosphotriesterase
PTE_C23_6 To Be Published
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8QCI
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![BU of 8qci by Molmil](/molmil-images/mine/8qci) | FCGBP D10 Assembly Segment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ... | Authors: | Yeshaya, N, Fass, D. | Deposit date: | 2023-08-27 | Release date: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | VWD domain stabilization by autocatalytic Asp-Pro cleavage. Protein Sci., 33, 2024
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7RQC
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![BU of 7rqc by Molmil](/molmil-images/mine/7rqc) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site MFI-tripeptidyl-tRNA analog ACCA-IFM at 2.50A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. | Deposit date: | 2021-08-06 | Release date: | 2022-01-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol. Nat.Struct.Mol.Biol., 29, 2022
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7RKM
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![BU of 7rkm by Molmil](/molmil-images/mine/7rkm) | Structure of CX3CL1-US28-Gi-scFv16 in C-state | Descriptor: | Antibody fragment scFv16, CHOLESTEROL, Fractalkine, ... | Authors: | Tsutsumi, N, Qu, Q, Jude, K.M, Skiniotis, G, Garcia, K.C. | Deposit date: | 2021-07-22 | Release date: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins Sci Adv, 8, 2022
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7RQB
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![BU of 7rqb by Molmil](/molmil-images/mine/7rqb) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site aminoacyl-tRNA analog ACC-PMN, and P-site MAI-tripeptidyl-tRNA analog ACCA-IAM at 2.45A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. | Deposit date: | 2021-08-06 | Release date: | 2022-01-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol. Nat.Struct.Mol.Biol., 29, 2022
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7RQD
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![BU of 7rqd by Molmil](/molmil-images/mine/7rqd) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site deacylated tRNA analog CACCA, P-site MTI-tripeptidyl-tRNA analog ACCA-ITM, and chloramphenicol at 2.50A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. | Deposit date: | 2021-08-06 | Release date: | 2022-01-26 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol. Nat.Struct.Mol.Biol., 29, 2022
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4YHH
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![BU of 4yhh by Molmil](/molmil-images/mine/4yhh) | Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with tigecycline | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Schedlbauer, A, Kaminishi, T, Ochoa-Lizarralde, B, Dhimole, N, Zhou, S, Lopez-Alonso, J.P, Connell, S.R, Fucini, P. | Deposit date: | 2015-02-27 | Release date: | 2015-04-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.417 Å) | Cite: | Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome. Antimicrob.Agents Chemother., 59, 2015
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7RKX
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![BU of 7rkx by Molmil](/molmil-images/mine/7rkx) | Structure of US27-Gi-scFv16 in CL-state | Descriptor: | Antibody fragment scFv16, G-protein coupled receptor homolog US27, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Tsutsumi, N, Jude, K.M, Garcia, K.C. | Deposit date: | 2021-07-22 | Release date: | 2022-01-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Atypical structural snapshots of human cytomegalovirus GPCR interactions with host G proteins Sci Adv, 8, 2022
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6G52
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![BU of 6g52 by Molmil](/molmil-images/mine/6g52) | CRYSTAL STRUCTURE OF THE CNMP BINDING DOMAIN OF THE MAGNESIUM TRANSPORTER CNNM4 | Descriptor: | Metal transporter CNNM4 | Authors: | Gimenez, P, Oyenarte, I, Hardy, S, Zubillaga, M, Merino, N, Blanco, F.J, Siliqi, D, Tremblay, M, Muller, D, Martinez-Cruz, L.A. | Deposit date: | 2018-03-28 | Release date: | 2019-04-10 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (3.691 Å) | Cite: | Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4. Int J Mol Sci, 20, 2019
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8QX5
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![BU of 8qx5 by Molmil](/molmil-images/mine/8qx5) | Helical Carotenoid Protein 4 (HCP4) from Anabaena with bound Canthaxanthin | Descriptor: | Orange carotenoid-binding domain-containing protein, beta,beta-carotene-4,4'-dione | Authors: | Sklyar, J, Wilson, A, Kirilovsky, D, Adir, N. | Deposit date: | 2023-10-22 | Release date: | 2024-04-03 | Last modified: | 2024-04-10 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Insights into energy quenching mechanisms and carotenoid uptake by orange carotenoid protein homologs: HCP4 and CTDH. Int.J.Biol.Macromol., 265, 2024
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7RQE
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![BU of 7rqe by Molmil](/molmil-images/mine/7rqe) | Crystal structure of the Thermus thermophilus 70S ribosome in complex with protein Y, A-site deacylated tRNA analog CACCA, P-site MAI-tripeptidyl-tRNA analog ACCA-IAM, and chloramphenicol at 2.40A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Syroegin, E.A, Flemmich, L, Klepacki, D, Vazquez-Laslop, N, Micura, R, Polikanov, Y.S. | Deposit date: | 2021-08-06 | Release date: | 2022-01-26 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for the context-specific action of the classic peptidyl transferase inhibitor chloramphenicol. Nat.Struct.Mol.Biol., 29, 2022
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4YNK
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![BU of 4ynk by Molmil](/molmil-images/mine/4ynk) | Crystal structure of vitamin D receptor ligand binding domain complexed with a 19-norvitamin D compound | Descriptor: | (1R,3R,7E,17beta)-17-{(5S)-5-hydroxy-5-[(3R,5R,7R)-tricyclo[3.3.1.1~3,7~]dec-1-yl]penta-1,3-diyn-1-yl}-2-methylidene-9,10-secoestra-5,7-diene-1,3-diol, Coactivator peptide drip from cDNA FLJ50196, highly similar to Peroxisome proliferator-activated receptor-binding protein, ... | Authors: | Watarai, Y, Ikura, T, Ito, N. | Deposit date: | 2015-03-10 | Release date: | 2016-01-20 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Synthesis, Biological Activities, and X-ray Crystal Structural Analysis of 25-Hydroxy-25(or 26)-adamantyl-17-[20(22),23-diynyl]-21-norvitamin D Compounds J.Med.Chem., 58, 2015
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6G32
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![BU of 6g32 by Molmil](/molmil-images/mine/6g32) | Crystal structure of human geranylgeranyl diphosphate synthase mutant D188Y | Descriptor: | GLYCEROL, Geranylgeranyl pyrophosphate synthase | Authors: | Lisnyansky, M, Kapelushnik, N, Ben-Bassat, A, Marom, M, Loewenstein, A, Khananshvili, D, Giladi, M, Haitin, Y. | Deposit date: | 2018-03-24 | Release date: | 2018-10-17 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.281 Å) | Cite: | Reduced Activity of Geranylgeranyl Diphosphate Synthase Mutant Is Involved in Bisphosphonate-Induced Atypical Fractures. Mol. Pharmacol., 94, 2018
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8P24
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![BU of 8p24 by Molmil](/molmil-images/mine/8p24) | |