4YC2
Crystal structure of the stabilized inner domain of clade A/E HIV-1 gp120 from E. coli in complex with the antibody A32.
Summary for 4YC2
Entry DOI | 10.2210/pdb4yc2/pdb |
Related | 3TNM 4H8W 4RQH 4YBL |
Descriptor | The stabilized inner domain of clade A/E HIV-1 gp120 from E. coli, The antibody A32 Fab heavy chain., The antibody A32 Fab light chain., ... (4 entities in total) |
Functional Keywords | adcc, non-neutralizing, anti-hiv-1 env antibody a32, cd4i antibody, clade a/e 93th057, viral protein, viral protein-immune system complex, viral protein/immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 6 |
Total formula weight | 127131.65 |
Authors | Tolbert, W.D.,Gohain, N.,Pazgier, M. (deposition date: 2015-02-19, release date: 2016-03-02, Last modification date: 2023-09-27) |
Primary citation | Tolbert, W.D.,Gohain, N.,Veillette, M.,Chapleau, J.P.,Orlandi, C.,Visciano, M.L.,Ebadi, M.,DeVico, A.L.,Fouts, T.R.,Finzi, A.,Lewis, G.K.,Pazgier, M. Paring Down HIV Env: Design and Crystal Structure of a Stabilized Inner Domain of HIV-1 gp120 Displaying a Major ADCC Target of the A32 Region. Structure, 24:697-709, 2016 Cited by PubMed: 27041594DOI: 10.1016/j.str.2016.03.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.02 Å) |
Structure validation
Download full validation report