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PDB: 17122 results

1KWK
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Crystal structure of Thermus thermophilus A4 beta-galactosidase in complex with galactose
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, BETA-GALACTOSIDASE, ...
Authors:Hidaka, M, Fushinobu, S, Ohtsu, N, Motoshima, H, Matsuzawa, H, Shoun, H, Wakagi, T.
Deposit date:2002-01-29
Release date:2002-10-02
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Trimeric crystal structure of the glycoside hydrolase family 42 beta-galactosidase from Thermus thermophilus A4 and the structure of its complex with galactose.
J.Mol.Biol., 322, 2002
1KM1
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Orotidine monophosphate decarboxylase mutant S127A crystal structure
Descriptor: 6-AZA URIDINE 5'-MONOPHOSPHATE, OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
Authors:Wu, N, Gillon, W, Pai, E.F.
Deposit date:2001-12-13
Release date:2002-06-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Mapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallography.
Biochemistry, 41, 2002
1JB6
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Crystal Structure of Dimerization Domain (1-33) of HNF-1alpha
Descriptor: HEPATOCYTE NUCLEAR FACTOR 1-ALPHA
Authors:Narayana, N, Hua, Q.-X, Weiss, M.A.
Deposit date:2001-06-01
Release date:2001-07-11
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:The dimerization domain of HNF-1alpha: structure and plasticity of an intertwined four-helix bundle with application to diabetes mellitus.
J.Mol.Biol., 310, 2001
1JEI
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LEM DOMAIN OF HUMAN INNER NUCLEAR MEMBRANE PROTEIN EMERIN
Descriptor: EMERIN
Authors:Wolff, N, Gilquin, B, Courchay, K, Callebaut, I, Zinn-Justin, S.
Deposit date:2001-06-18
Release date:2001-07-04
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Structural analysis of emerin, an inner nuclear membrane protein mutated in X-linked Emery-Dreifuss muscular dystrophy
FEBS LETT., 501, 2001
1K9M
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Co-crystal structure of tylosin bound to the 50S ribosomal subunit of Haloarcula marismortui
Descriptor: 23S RRNA, 5S RRNA, CADMIUM ION, ...
Authors:Hansen, J.L, Ippolito, J.A, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A.
Deposit date:2001-10-29
Release date:2002-07-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structures of four macrolide antibiotics bound to the large ribosomal subunit.
Mol.Cell, 10, 2002
1KM5
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Crystal structure of ODCase mutant D75N complexed with 6-azaUMP
Descriptor: 6-AZA URIDINE 5'-MONOPHOSPHATE, CHLORIDE ION, OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
Authors:Wu, N, Gillon, W, Pai, E.F.
Deposit date:2001-12-13
Release date:2002-06-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallography.
Biochemistry, 41, 2002
1KLY
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Orotidine monophosphate decarboxylase D70G mutant complexed with 6-azaUMP
Descriptor: 6-AZA URIDINE 5'-MONOPHOSPHATE, OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
Authors:Wu, N, Gillon, W, Pai, E.F.
Deposit date:2001-12-13
Release date:2002-06-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallography.
Biochemistry, 41, 2002
1KM4
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crystal structure of ODCase mutant K72A complexed with UMP
Descriptor: OROTIDINE 5'-PHOSPHATE DECARBOXYLASE, URIDINE-5'-MONOPHOSPHATE
Authors:Wu, N, Gillon, W, Pai, E.F.
Deposit date:2001-12-13
Release date:2002-06-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallography.
Biochemistry, 41, 2002
1KKD
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Solution structure of the calmodulin binding domain (CaMBD) of small conductance Ca2+-activated potassium channels (SK2)
Descriptor: Small conductance calcium-activated potassium channel protein 2
Authors:Wissmann, R, Bildl, W, Neumann, H, Rivard, A.F, Kloecker, N, Weitz, D, Schulte, U, Adelman, J.P, Bentrop, D, Fakler, B.
Deposit date:2001-12-07
Release date:2001-12-14
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A helical region in the C terminus of small-conductance Ca2+-activated K+ channels controls assembly with apo-calmodulin.
J.Biol.Chem., 277, 2002
1KD1
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Co-crystal Structure of Spiramycin bound to the 50S Ribosomal Subunit of Haloarcula marismortui
Descriptor: 23S RRNA, 5S RRNA, CADMIUM ION, ...
Authors:Hansen, J.L, Ippolito, J.A, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A.
Deposit date:2001-11-12
Release date:2002-07-19
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3 Å)
Cite:The structures of four macrolide antibiotics bound to the large ribosomal subunit.
Mol.Cell, 10, 2002
1KC8
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Co-crystal Structure of Blasticidin S Bound to the 50S Ribosomal Subunit
Descriptor: 23S RRNA, 5S RRNA, BLASTICIDIN S, ...
Authors:Hansen, J.L, Ban, N, Nissen, P, Moore, P.B, Steitz, T.A.
Deposit date:2001-11-07
Release date:2003-07-22
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
J.Mol.Biol., 330, 2003
1KM2
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crystal structure of orotidine monophosphate mutant Q185A with 6-azaUMP
Descriptor: 6-AZA URIDINE 5'-MONOPHOSPHATE, OROTIDINE 5'-PHOSPHATE DECARBOXYLASE
Authors:Wu, N, Gillon, W, Pai, E.F.
Deposit date:2001-12-13
Release date:2002-06-28
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Mapping the active site-ligand interactions of orotidine 5'-monophosphate decarboxylase by crystallography.
Biochemistry, 41, 2002
1KWG
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Crystal structure of Thermus thermophilus A4 beta-galactosidase
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, BETA-GALACTOSIDASE, ...
Authors:Hidaka, M, Fushinobu, S, Ohtsu, N, Motoshima, H, Matsuzawa, H, Shoun, H, Wakagi, T.
Deposit date:2002-01-29
Release date:2002-09-18
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Trimeric Crystal Structure of the Glycoside Hydrolase Family 42 beta-Galactosidase from Thermus thermophilus A4 and the Structure of its Complex with Galactose
J.MOL.BIOL., 322, 2002
1KVD
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KILLER TOXIN FROM HALOTOLERANT YEAST
Descriptor: SMK TOXIN, SULFATE ION
Authors:Kashiwagi, T, Kunishima, N, Suzuki, C, Tsuchiya, F, Nikkuni, S, Arata, Y, Morikawa, K.
Deposit date:1996-10-04
Release date:1997-04-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The novel acidophilic structure of the killer toxin from halotolerant yeast demonstrates remarkable folding similarity with a fungal killer toxin.
Structure, 5, 1997
2P6L
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Crystal structure of PH0725 from Pyrococcus horikoshii OT3
Descriptor: S-ADENOSYL-L-HOMOCYSTEINE, diphthine synthase
Authors:Yamamoto, H, Matsuura, Y, Ono, N, Shimada, H, Kunishima, N, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2007-03-19
Release date:2007-09-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of PH0725 from Pyrococcus horikoshii OT3
To be Published
2P8U
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Crystal structure of human 3-hydroxy-3-methylglutaryl CoA synthase I
Descriptor: COENZYME A, GLYCEROL, Hydroxymethylglutaryl-CoA synthase, ...
Authors:Turnbull, A, Shafqat, N, Salah, E, Niesen, F.H, Burgess, N, Bunkoczi, G, Debreczeni, J, Pike, A.C.W, Umeano, C, Gorrec, F, von Delft, F, Weigelt, J, Arrowsmith, C.H, Sundstrom, M, Edwards, A, Oppermann, U, Structural Genomics Consortium (SGC)
Deposit date:2007-03-23
Release date:2007-04-03
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structures of human HMG-CoA synthase isoforms provide insights into inherited ketogenesis disorders and inhibitor design.
J.Mol.Biol., 398, 2010
8E34
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CryoEM structures of bAE1 captured in multiple states
Descriptor: Anion exchange protein
Authors:Zhekova, H.R, Wang, W.G, Jiang, J.S, Tsirulnikov, K, Muhammad-Khan, G.H, Azimov, R, Abuladze, N, Kao, L, Newman, D, Noskov, S.Y, Tieleman, P, Zhou, Z.H, Pushkin, A, Kurtz, I.
Deposit date:2022-08-16
Release date:2023-01-25
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (6 Å)
Cite:CryoEM structures of anion exchanger 1 capture multiple states of inward- and outward-facing conformations.
Commun Biol, 5, 2022
8VLX
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HTT in complex with HAP40 and a small molecule.
Descriptor: 40-kDa huntingtin-associated protein, Huntingtin, N-[(1S,2R)-2-benzylcyclopentyl]-N'-{1-[(1S)-1-(pyridin-4-yl)ethyl]piperidin-4-yl}urea
Authors:Poweleit, N, Boudet, J, Doherty, E.
Deposit date:2024-01-12
Release date:2024-03-06
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Discovery of a Small Molecule Ligand to the Huntingtin/HAP40 complex
To Be Published
8E10
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Structure of mouse polymerase beta
Descriptor: DNA polymerase beta, MALONIC ACID
Authors:Thompson, M.K, Sharma, N, Prakash, A.
Deposit date:2022-08-09
Release date:2023-02-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.65 Å)
Cite:Pol beta /XRCC1 heterodimerization dictates DNA damage recognition and basal Pol beta protein levels without interfering with mouse viability or fertility.
DNA Repair (Amst), 123, 2023
1V4N
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Structure of 5'-deoxy-5'-methylthioadenosine phosphorylase homologue from Sulfolobus tokodaii
Descriptor: 271aa long hypothetical 5'-methylthioadenosine phosphorylase
Authors:Kitago, Y, Yasutake, Y, Sakai, N, Tsujimura, M, Yao, M, Watanabe, N, Kawarabayasi, Y, Tanaka, I.
Deposit date:2003-11-14
Release date:2005-01-04
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Crystal structure of Sulfolobus tokodaii MTAP
To be Published
8E11
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Structure of mouse DNA polymerase Beta (PolB) mutant
Descriptor: ACETATE ION, DNA polymerase beta, MALONIC ACID
Authors:Sharma, N, Thompson, M.K, Prakash, A.
Deposit date:2022-08-09
Release date:2023-02-01
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Pol beta /XRCC1 heterodimerization dictates DNA damage recognition and basal Pol beta protein levels without interfering with mouse viability or fertility.
DNA Repair (Amst), 123, 2023
1V30
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Crystal Structure Of Uncharacterized Protein PH0828 From Pyrococcus horikoshii
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Hypothetical UPF0131 protein PH0828
Authors:Tajika, Y, Sakai, N, Yao, M, Watanabe, N, Tanaka, I.
Deposit date:2003-10-21
Release date:2004-11-09
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Crystal structure of hypothetical protein PH0828 from Pyrococcus horikoshii.
Proteins, 57, 2004
1LOT
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CRYSTAL STRUCTURE OF THE COMPLEX OF ACTIN WITH VITAMIN D-BINDING PROTEIN
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
Authors:Head, J.F, Swamy, N, Ray, R.
Deposit date:2002-05-07
Release date:2002-07-31
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of the complex between actin and human vitamin D-binding protein at 2.5 A resolution.
Biochemistry, 41, 2002
1LS2
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Fitting of EF-Tu and tRNA in the Low Resolution Cryo-EM Map of an EF-Tu Ternary Complex (GDP and Kirromycin) Bound to E. coli 70S Ribosome
Descriptor: Elongation Factor Tu, Phenylalanine transfer RNA
Authors:Valle, M, Sengupta, J, Swami, N.K, Grassucci, R.A, Burkhardt, N, Nierhaus, K.H, Agrawal, R.K, Frank, J.
Deposit date:2002-05-16
Release date:2002-06-26
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (16.799999 Å)
Cite:Cryo-EM reveals an active role for aminoacyl-tRNA in the accommodation process.
EMBO J., 21, 2002
1LOR
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crystal structure of orotidine 5'-monophosphate complexed with BMP
Descriptor: 6-HYDROXYURIDINE-5'-PHOSPHATE, orotidine monophosphate decarboxylase
Authors:Wu, N, Pai, E.F.
Deposit date:2002-05-06
Release date:2002-08-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Crystal structures of inhibitor complexes reveal an alternate binding mode in orotidine-5'-monophosphate decarboxylase.
J.Biol.Chem., 277, 2002

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