7NSH
| 39S mammalian mitochondrial large ribosomal subunit with mtRRF (post) and mtEFG2 | 分子名称: | 16S rRNA, 39S ribosomal protein L48, mitochondrial, ... | 著者 | Kummer, E, Schubert, K, Ban, N. | 登録日 | 2021-03-07 | 公開日 | 2021-05-05 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis of translation termination, rescue, and recycling in mammalian mitochondria. Mol.Cell, 81, 2021
|
|
7P47
| Structure of the E3 ligase Smc5/Nse2 in complex with Ubc9-SUMO thioester mimetic | 分子名称: | E3 SUMO-protein ligase MMS21, SUMO-conjugating enzyme UBC9, Structural maintenance of chromosomes protein 5, ... | 著者 | Lascorz, J, Varejao, N, Reverter, D. | 登録日 | 2021-07-09 | 公開日 | 2021-11-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3.314 Å) | 主引用文献 | Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs. Nat Commun, 12, 2021
|
|
7OVB
| L. pneumophila Type IV Coupling Complex (T4CC) with density for DotY N-terminal and middle domains | 分子名称: | DotY, DotZ, IcmJ (DotN), ... | 著者 | Mace, K, Meir, A, Lukoyanova, N, Waksman, G. | 登録日 | 2021-06-14 | 公開日 | 2021-12-01 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.61 Å) | 主引用文献 | Proteins DotY and DotZ modulate the dynamics and localization of the type IVB coupling complex of Legionella pneumophila. Mol.Microbiol., 117, 2022
|
|
7OTI
| Structure of ABCB1/P-glycoprotein in apo state | 分子名称: | Multidrug resistance protein 1A | 著者 | Ford, R.C, Barbieri, A, Thonghin, N, Shafi, T, Prince, S.M, Collins, R.F. | 登録日 | 2021-06-10 | 公開日 | 2021-12-08 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Structure of ABCB1/P-Glycoprotein in the Presence of the CFTR Potentiator Ivacaftor. Membranes (Basel), 11, 2021
|
|
7NQH
| 55S mammalian mitochondrial ribosome with mtRF1a and P-site tRNAMet | 分子名称: | 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ... | 著者 | Kummer, E, Schubert, K, Ban, N. | 登録日 | 2021-03-01 | 公開日 | 2021-05-05 | 最終更新日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Structural basis of translation termination, rescue, and recycling in mammalian mitochondria. Mol.Cell, 81, 2021
|
|
7OAK
| Crystal structure of pseudokinase CASK in complex with compound 26 | 分子名称: | 1,2-ETHANEDIOL, 2-[[2,5-bis(bromanyl)-4-methyl-phenyl]methylamino]-4-(cyclopentylamino)-N-[3-(2-oxidanylidene-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamide, Peripheral plasma membrane protein CASK | 著者 | Chaikuad, A, Russ, N, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-04-19 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | 主引用文献 | Design and Development of a Chemical Probe for Pseudokinase Ca 2+ /calmodulin-Dependent Ser/Thr Kinase. J.Med.Chem., 64, 2021
|
|
7OAJ
| Crystal structure of pseudokinase CASK in complex with compound 7 | 分子名称: | 1,2-ETHANEDIOL, 4-(cyclopentylamino)-2-[(3,4-dichlorophenyl)methylamino]-N-[3-(2-oxidanylidenepyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide, Peripheral plasma membrane protein CASK | 著者 | Chaikuad, A, Russ, N, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-04-19 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Design and Development of a Chemical Probe for Pseudokinase Ca 2+ /calmodulin-Dependent Ser/Thr Kinase. J.Med.Chem., 64, 2021
|
|
7OAL
| Crystal structure of pseudokinase CASK in complex with compound 25 | 分子名称: | 1,2-ETHANEDIOL, 2-[[2,5-bis(bromanyl)-4-methyl-phenyl]methylamino]-4-(cyclohexylamino)-N-[3-(2-oxidanylidene-1,3-oxazolidin-3-yl)propyl]pyrimidine-5-carboxamide, Peripheral plasma membrane protein CASK | 著者 | Chaikuad, A, Russ, N, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-04-19 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Design and Development of a Chemical Probe for Pseudokinase Ca 2+ /calmodulin-Dependent Ser/Thr Kinase. J.Med.Chem., 64, 2021
|
|
5EQL
| Isoform-specific inhibition of SUMO-dependent protein-protein interactions | 分子名称: | SUMO-Affirmer-S2D5, Small ubiquitin-related modifier 2 | 著者 | Hughes, D.J, Tiede, C, Hall, N, Tang, A.A.S, Trinh, C.H, Zajac, K, Mandal, U, Howell, G, Edwards, T.A, McPherson, M.J, Tomlinson, D.C, Whitehouse, A. | 登録日 | 2015-11-13 | 公開日 | 2016-11-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Generation of specific inhibitors of SUMO-1- and SUMO-2/3-mediated protein-protein interactions using Affimer (Adhiron) technology. Sci Signal, 10, 2017
|
|
7OAM
| Kinase domain of MERTK in complex with compound 8 | 分子名称: | 1,2-ETHANEDIOL, 2-[[2,5-bis(fluoranyl)phenyl]methylamino]-4-(cyclopentylamino)-N-[3-(2-oxidanylidenepyrrolidin-1-yl)propyl]pyrimidine-5-carboxamide, Tyrosine-protein kinase Mer | 著者 | Schroeder, M, Russ, N, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-04-19 | 公開日 | 2021-05-19 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Design and Development of a Chemical Probe for Pseudokinase Ca 2+ /calmodulin-Dependent Ser/Thr Kinase. J.Med.Chem., 64, 2021
|
|
7NSI
| 55S mammalian mitochondrial ribosome with mtRRF (pre) and tRNA(P/E) | 分子名称: | 12S rRNA, 16S rRNA, 28S ribosomal protein S10, ... | 著者 | Kummer, E, Schubert, K, Ban, N. | 登録日 | 2021-03-07 | 公開日 | 2021-06-02 | 最終更新日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Structural basis of translation termination, rescue, and recycling in mammalian mitochondria. Mol.Cell, 81, 2021
|
|
7NSJ
| 55S mammalian mitochondrial ribosome with tRNA(P/P) and tRNA(E*) | 分子名称: | 12S rRNA, 16S rRNA, 28S ribosomal protein S16, ... | 著者 | Kummer, E, Schubert, K, Ban, N. | 登録日 | 2021-03-07 | 公開日 | 2021-06-02 | 最終更新日 | 2021-12-15 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structural basis of translation termination, rescue, and recycling in mammalian mitochondria. Mol.Cell, 81, 2021
|
|
7NWL
| Cryo-EM structure of human integrin alpha5beta1 (open form) in complex with fibronectin and TS2/16 Fv-clasp | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-5, ... | 著者 | Schumacher, S, Dedden, D, Vazquez Nunez, R, Matoba, K, Takagi, J, Biertumpfel, C, Mizuno, N. | 登録日 | 2021-03-17 | 公開日 | 2021-06-02 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural insights into integrin alpha 5 beta 1 opening by fibronectin ligand. Sci Adv, 7, 2021
|
|
7O80
| Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated SARS-CoV-2 slippery site | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
|
|
7O81
| Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
|
|
7O7Y
| Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high resolution) | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
|
|
7O7Z
| Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (classified for pseudoknot) | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | 登録日 | 2021-04-14 | 公開日 | 2021-06-02 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome. Science, 372, 2021
|
|
2NSO
| Trna-gunanine-transglycosylase (TGT) mutant Y106F, C158V, A232S, V233G- APO-Structure | 分子名称: | GLYCEROL, Queuine tRNA-ribosyltransferase, ZINC ION | 著者 | Tidten, N, Heine, A, Reuter, K, Klebe, G. | 登録日 | 2006-11-06 | 公開日 | 2007-12-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Investigation of Specificity Determinants in Bacterial tRNA-Guanine Transglycosylase Reveals Queuine, the Substrate of Its Eucaryotic Counterpart, as Inhibitor. Plos One, 8, 2013
|
|
7OTG
| Structure of ABCB1/P-glycoprotein in the presence of the CFTR potentiator ivacaftor | 分子名称: | Multidrug resistance protein 1A, N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide | 著者 | Ford, R.C, Barbieri, A, Thonghin, N, Shafi, T, Prince, S.M, Collins, R.F. | 登録日 | 2021-06-10 | 公開日 | 2021-12-08 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (5.4 Å) | 主引用文献 | Structure of ABCB1/P-Glycoprotein in the Presence of the CFTR Potentiator Ivacaftor. Membranes (Basel), 11, 2021
|
|
7OSA
| Pre-translocation complex of 80 S.cerevisiae ribosome with eEF2 and ligands | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ... | 著者 | Djumagulov, M, Jenner, L, Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2021-06-08 | 公開日 | 2021-12-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Accuracy mechanism of eukaryotic ribosome translocation. Nature, 600, 2021
|
|
7P5X
| Mycobacterial RNAP with transcriptional activator PafBC | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Mueller, A.U, Kummer, E, Schilling, C.M, Ban, N, Weber-Ban, E. | 登録日 | 2021-07-15 | 公開日 | 2021-12-22 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Transcriptional control of mycobacterial DNA damage response by sigma adaptation. Sci Adv, 7, 2021
|
|
7OXO
| human LonP1, R-state, incubated in AMPPCP | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Lon protease homolog, mitochondrial | 著者 | Abrahams, J.P, Mohammed, I, Schmitz, K.A, Schenck, N, Maier, T. | 登録日 | 2021-06-22 | 公開日 | 2021-12-22 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Catalytic cycling of human mitochondrial Lon protease. Structure, 30, 2022
|
|
8ALO
| Heterodimer formation of sensory domains of Vibrio cholerae regulators ToxR and ToxS | 分子名称: | Cholera toxin transcriptional activator, Transmembrane regulatory protein ToxS | 著者 | Gubensaek, N, Sagmeister, T, Pavkov-Keller, T, Zangger, K, Buhlheller, C, Wagner, G.E. | 登録日 | 2022-08-01 | 公開日 | 2023-09-13 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (3.002 Å) | 主引用文献 | Vibrio cholerae's ToxRS bile sensing system. Elife, 12, 2023
|
|
7OSM
| Intermediate translocation complex of 80 S.cerevisiae ribosome with eEF2 and ligands | 分子名称: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0, ... | 著者 | Djumagulov, M, Jenner, L, Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | 登録日 | 2021-06-09 | 公開日 | 2021-12-08 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Accuracy mechanism of eukaryotic ribosome translocation. Nature, 600, 2021
|
|
7BV3
| Crystal structure of a ugt transferase from Siraitia grosvenorii in complex with UDP | 分子名称: | Glycosyltransferase, URIDINE-5'-DIPHOSPHATE | 著者 | Li, J, Shan, N, Yang, J.G, Liu, W.D, Sun, Y.X. | 登録日 | 2020-04-09 | 公開日 | 2021-03-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Near-perfect control of the regioselective glucosylation enabled by rational design of glycosyltransferases Green Synth Catal, 2021
|
|