7JXE
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![BU of 7jxe by Molmil](/molmil-images/mine/7jxe) | Mapping neutralizing and immunodominant sites on the SARS-CoV-2 spike receptor-binding domain by structure-guided high-resolution serology | 分子名称: | S2X35 antigen-binding (Fab) fragment | 著者 | Tortorici, M.A, Park, Y.J, Walls, A.C, Czudnochowski, N, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Snell, G, Veesler, D. | 登録日 | 2020-08-27 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.043 Å) | 主引用文献 | Mapping Neutralizing and Immunodominant Sites on the SARS-CoV-2 Spike Receptor-Binding Domain by Structure-Guided High-Resolution Serology. Cell, 183, 2020
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6PJC
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![BU of 6pjc by Molmil](/molmil-images/mine/6pjc) | HIV-1 Protease NL4-3 WT in Complex with LR4-41 | 分子名称: | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,4S,5S)-5-{[(2,6-dimethylphenoxy)acetyl]amino}-4-hydroxy-1,6-diphenylhexan-2-yl]carbamate, Protease NL4-3, SULFATE ION | 著者 | Lockbaum, G.J, Rusere, L.N, Henes, M, Kosovrasti, K, Lee, S.K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. | 登録日 | 2019-06-28 | 公開日 | 2020-07-01 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.965 Å) | 主引用文献 | Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-tetrahydrofuran in a Pseudosymmetric Dipeptide Isostere. J.Med.Chem., 63, 2020
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5IX6
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![BU of 5ix6 by Molmil](/molmil-images/mine/5ix6) | X-ray structure of Auoxo3-encapsulated horse spleen apoferritin | 分子名称: | CADMIUM ION, Ferritin light chain, GOLD ION, ... | 著者 | Ferraro, G, Pontillo, N, Merlino, A. | 登録日 | 2016-03-23 | 公開日 | 2016-07-06 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Gold-based drug encapsulation within a ferritin nanocage: X-ray structure and biological evaluation as a potential anticancer agent of the Auoxo3-loaded protein. Chem.Commun.(Camb.), 52, 2016
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5IXB
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![BU of 5ixb by Molmil](/molmil-images/mine/5ixb) | Structure of human Melanoma Inhibitory Activity (MIA) Protein in complex with Pyrimidin-2-amine | 分子名称: | ACETATE ION, Melanoma-derived growth regulatory protein, PYRIMIDIN-2-AMINE | 著者 | Yip, K.T, Gasper, R, Zhong, X.Y, Seibel, N, Puetz, S, Autzen, J, Scherkenbeck, J, Hofmann, E, Stoll, R. | 登録日 | 2016-03-23 | 公開日 | 2016-08-17 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Small Molecules Antagonise the MIA-Fibronectin Interaction in Malignant Melanoma. Sci Rep, 6, 2016
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7JPE
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![BU of 7jpe by Molmil](/molmil-images/mine/7jpe) | Room Temperature Structure of SARS-CoV-2 Nsp10/Nsp16 Methyltransferase in a Complex with m7GpppA Cap-0 and SAM Determined by Fixed-Target Serial Crystallography | 分子名称: | 2'-O-methyltransferase, 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, Non-structural protein 10, ... | 著者 | Wilamowski, M, Sherrell, D.A, Minasov, G, Kim, Y, Shuvalova, L, Lavens, A, Chard, R, Rosas-Lemus, M, Maltseva, N, Jedrzejczak, R, Michalska, K, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-08-07 | 公開日 | 2020-08-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | 2'-O methylation of RNA cap in SARS-CoV-2 captured by serial crystallography. Proc.Natl.Acad.Sci.USA, 118, 2021
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7QOF
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![BU of 7qof by Molmil](/molmil-images/mine/7qof) | Icosahedral capsid of the phicrAss001 virion | 分子名称: | Auxiliary capsid protein gp36, Head fiber dimer protein gp29, Head fiber trimer protein gp21, ... | 著者 | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | 登録日 | 2021-12-24 | 公開日 | 2023-03-29 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Structural atlas of a human gut crassvirus. Nature, 617, 2023
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7QOG
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![BU of 7qog by Molmil](/molmil-images/mine/7qog) | Portal protein assembly of the phicrAss001 virion with C12 symmetry imposed | 分子名称: | Cargo protein 1 gp45, Portal protein gp20, Ring protein 1 gp43, ... | 著者 | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | 登録日 | 2021-12-24 | 公開日 | 2023-03-29 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | 主引用文献 | Structural atlas of a human gut crassvirus. Nature, 617, 2023
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7QOH
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![BU of 7qoh by Molmil](/molmil-images/mine/7qoh) | Unique vertex of the phicrAss001 virion with C5 symmetry imposed | 分子名称: | Auxiliary capsid protein gp36, Head fiber trimer protein gp21, MAGNESIUM ION, ... | 著者 | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | 登録日 | 2021-12-24 | 公開日 | 2023-03-29 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | 主引用文献 | Structural atlas of a human gut crassvirus. Nature, 617, 2023
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5JNS
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![BU of 5jns by Molmil](/molmil-images/mine/5jns) | Crystal structure of human low molecular weight protein tyrosine phosphatase (LMPTP) type A complexed with phosphate | 分子名称: | DIMETHYL SULFOXIDE, Low molecular weight phosphotyrosine protein phosphatase, PHOSPHATE ION | 著者 | Stanford, S.M, Aleshin, A.E, Liddington, R.C, Bankston, L, Cadwell, G, Bottini, N. | 登録日 | 2016-04-30 | 公開日 | 2017-03-29 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Diabetes reversal by inhibition of the low-molecular-weight tyrosine phosphatase. Nat. Chem. Biol., 13, 2017
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7QOK
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![BU of 7qok by Molmil](/molmil-images/mine/7qok) | Tail muzzle assembly of the phicrAss001 virion with C6 symmetry imposed | 分子名称: | MAGNESIUM ION, Muzzle bound helix, Muzzle protein gp44, ... | 著者 | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | 登録日 | 2021-12-24 | 公開日 | 2023-03-29 | 最終更新日 | 2024-07-17 | 実験手法 | ELECTRON MICROSCOPY (3.38 Å) | 主引用文献 | Structural atlas of a human gut crassvirus. Nature, 617, 2023
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7QOJ
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![BU of 7qoj by Molmil](/molmil-images/mine/7qoj) | Tail barrel assembly of the phicrAss001 virion with C12 symmetry imposed | 分子名称: | Cargo protein 1 gp45, MAGNESIUM ION, Portal protein gp20, ... | 著者 | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | 登録日 | 2021-12-24 | 公開日 | 2023-03-29 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.21 Å) | 主引用文献 | Structural atlas of a human gut crassvirus. Nature, 617, 2023
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7QOL
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![BU of 7qol by Molmil](/molmil-images/mine/7qol) | Tail assembly of the phicrAss001 virion with C6 symmetry imposed | 分子名称: | Cargo protein 1 gp45, MAGNESIUM ION, Muzzle bound helix, ... | 著者 | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | 登録日 | 2021-12-24 | 公開日 | 2023-03-29 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.33 Å) | 主引用文献 | Structural atlas of a human gut crassvirus. Nature, 617, 2023
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7QOI
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![BU of 7qoi by Molmil](/molmil-images/mine/7qoi) | Unique vertex of the phicrAss001 virion | 分子名称: | Auxiliary capsid protein gp36, Cargo protein 1 gp45, Head fiber trimer protein gp21, ... | 著者 | Bayfield, O.W, Shkoporov, A.N, Yutin, N, Khokhlova, E.V, Smith, J.L.R, Hawkins, D.E.D.P, Koonin, E.V, Hill, C, Antson, A.A. | 登録日 | 2021-12-24 | 公開日 | 2023-03-29 | 最終更新日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.62 Å) | 主引用文献 | Structural atlas of a human gut crassvirus. Nature, 617, 2023
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5J53
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![BU of 5j53 by Molmil](/molmil-images/mine/5j53) | The Structure and Mechanism of NOV1, a Resveratrol-Cleaving Dioxygenase | 分子名称: | Carotenoid oxygenase, FE (III) ION, OXYGEN MOLECULE, ... | 著者 | McAndrew, R.P, Pereira, J.H, Sathitsuksanoh, N, Sale, K.L, Simmons, B.A, Adams, P.D. | 登録日 | 2016-04-01 | 公開日 | 2016-11-30 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.61 Å) | 主引用文献 | Structure and mechanism of NOV1, a resveratrol-cleaving dioxygenase. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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6VTL
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5J6C
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![BU of 5j6c by Molmil](/molmil-images/mine/5j6c) | FMN-dependent Nitroreductase (CDR20291_0767) from Clostridium difficile R20291 | 分子名称: | FLAVIN MONONUCLEOTIDE, IMIDAZOLE, Putative reductase | 著者 | Powell, S.M, Wang, B, Hessami, N, Najar, F.Z, Thomas, L.M, West, A.H, Karr, E.A, Richter-Addo, G.B. | 登録日 | 2016-04-04 | 公開日 | 2016-09-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.096 Å) | 主引用文献 | Crystal structures of two nitroreductases from hypervirulent Clostridium difficile and functionally related interactions with the antibiotic metronidazole. Nitric Oxide, 60, 2016
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5J83
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![BU of 5j83 by Molmil](/molmil-images/mine/5j83) | |
5M1G
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![BU of 5m1g by Molmil](/molmil-images/mine/5m1g) | |
5J1V
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![BU of 5j1v by Molmil](/molmil-images/mine/5j1v) | Crystal structure of human CLK1 in complex with pyrido[3,4-g]quinazoline derivative ZW29 (compound 13) | 分子名称: | Dual specificity protein kinase CLK1, GLYCEROL, pyrido[3,4-g]quinazoline-2,10-diamine | 著者 | Chaikuad, A, Esvan, Y.J, Zeinyeh, W, Boibessot, T, Nauton, L, Thery, V, Loaec, N, Meijer, L, Giraud, F, Moreau, P, Anizon, F, von Delft, F, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2016-03-29 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Discovery of pyrido[3,4-g]quinazoline derivatives as CMGC family protein kinase inhibitors: Design, synthesis, inhibitory potency and X-ray co-crystal structure. Eur.J.Med.Chem., 118, 2016
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6VTK
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![BU of 6vtk by Molmil](/molmil-images/mine/6vtk) | |
5JK8
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![BU of 5jk8 by Molmil](/molmil-images/mine/5jk8) | |
5J84
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![BU of 5j84 by Molmil](/molmil-images/mine/5j84) | |
5JDB
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![BU of 5jdb by Molmil](/molmil-images/mine/5jdb) | Binding specificity of P[8] VP8* proteins of rotavirus vaccine strains with histo-blood group antigens | 分子名称: | Outer capsid protein VP4 | 著者 | Sun, X, Guo, N, Li, D, Zhou, Y, Jin, M, Xie, G, Pang, L, Zhang, Q, Cao, Y, Duan, Z. | 登録日 | 2016-04-16 | 公開日 | 2016-07-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Binding specificity of P[8] VP8* proteins of rotavirus vaccine strains with histo-blood group antigens. Virology, 495, 2016
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5JIJ
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![BU of 5jij by Molmil](/molmil-images/mine/5jij) | Structure of Mycobacterium thermoresistibile trehalose-6-phosphate synthase (APO form). | 分子名称: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Alpha,alpha-trehalose-phosphate synthase | 著者 | Mendes, V, Verma, N, Blaszczyk, M, Blundell, T.L. | 登録日 | 2016-04-22 | 公開日 | 2017-05-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Mycobacterial OtsA Structures Unveil Substrate Preference Mechanism and Allosteric Regulation by 2-Oxoglutarate and 2-Phosphoglycerate. Mbio, 10, 2019
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5JCP
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![BU of 5jcp by Molmil](/molmil-images/mine/5jcp) | RhoGAP domain of ARAP3 in complex with RhoA in the transition state | 分子名称: | Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3,Linker,Transforming protein RhoA, GUANOSINE-5'-DIPHOSPHATE, ... | 著者 | Bao, H, Li, F, Wang, C, Wang, N, Jiang, Y, Tang, Y, Wu, J, Shi, Y. | 登録日 | 2016-04-15 | 公開日 | 2016-06-22 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis for the Specific Recognition of RhoA by the Dual GTPase-activating Protein ARAP3 J.Biol.Chem., 291, 2016
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