6VTK

Structure of an acid-sensing ion channel solubilized by styrene maleic acid and in a desensitized state at low pH

Summary for 6VTK

Entry DOI	10.2210/pdb6vtk/pdb
EMDB information	21380
Descriptor	Acid-sensing ion channel 1, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
Functional Keywords	ion channel, ligand-gated ion channel, acid-sensing ion channel, asic, asic1a, proton-gated ion channel, membrane protein, transport protein
Biological source	Gallus gallus (Chicken)
Total number of polymer chains	3
Total formula weight	181568.22
Authors	Yoder, N.,Gouaux, E. (deposition date: 2020-02-12, release date: 2020-03-11, Last modification date: 2020-07-29)
Primary citation	Yoder, N.,Gouaux, E. The His-Gly motif of acid-sensing ion channels resides in a reentrant 'loop' implicated in gating and ion selectivity. Elife, 9:-, 2020 Cited by PubMed: 32496192 DOI: 10.7554/eLife.56527 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.82 Å)

Structure validation