6VTL

Structure of an acid-sensing ion channel solubilized by styrene maleic acid and in a resting state at high pH

Summary for 6VTL

• Entry DOI: 10.2210/pdb6vtl/pdb
• Related: 6VTK
• EMDB information: 21380 21381
• Descriptor: Acid-sensing ion channel 1, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total)
• Functional Keywords: ligand-gated ion channel, acid-sensing ion channel, asic, asic1a, proton-gated ion channel, membrane protein, transport protein
• Biological source: Gallus gallus (Chicken)
• Total number of polymer chains: 3
• Total formula weight: 181568.22

Authors

Yoder, N.,Gouaux, E. (deposition date: 2020-02-12, release date: 2020-03-11, Last modification date: 2020-07-29)

• Primary citation: Yoder, N.,Gouaux, E.; The His-Gly motif of acid-sensing ion channels resides in a reentrant 'loop' implicated in gating and ion selectivity.; Elife, 9:-, 2020; PubMed: 32496192; DOI: 10.7554/eLife.56527

Experimental method

ELECTRON MICROSCOPY (3.65 Å)