7UAU
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![BU of 7uau by Molmil](/molmil-images/mine/7uau) | The crystal structure of the K137A mutant of E. coli YGGS in complex with PLP | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein, SULFATE ION | Authors: | Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K. | Deposit date: | 2022-03-14 | Release date: | 2022-03-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability. Protein Sci., 31, 2022
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7UBP
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![BU of 7ubp by Molmil](/molmil-images/mine/7ubp) | The crystal structure of the K36A/K137A double mutant of E. coli YGGS in complex with PLP | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein, SULFATE ION | Authors: | Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K. | Deposit date: | 2022-03-15 | Release date: | 2022-03-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability. Protein Sci., 31, 2022
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7UAT
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![BU of 7uat by Molmil](/molmil-images/mine/7uat) | The crystal structure of the K36A mutant of E. coli YGGS in complex with PLP | Descriptor: | PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein | Authors: | Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K. | Deposit date: | 2022-03-14 | Release date: | 2022-03-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability. Protein Sci., 31, 2022
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7UB8
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![BU of 7ub8 by Molmil](/molmil-images/mine/7ub8) | The crystal structure of the K38A/K137A/K233A/K234A quadruple mutant of E. coli YGGS in complex with PLP | Descriptor: | 1,4-BUTANEDIOL, PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein | Authors: | Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K. | Deposit date: | 2022-03-14 | Release date: | 2022-03-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability. Protein Sci., 31, 2022
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7UBQ
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![BU of 7ubq by Molmil](/molmil-images/mine/7ubq) | The crystal structure of the wild-type of E. coli YGGS in complex with PNP | Descriptor: | PYRIDOXINE-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein | Authors: | Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K. | Deposit date: | 2022-03-15 | Release date: | 2022-03-23 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability. Protein Sci., 31, 2022
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7UD7
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![BU of 7ud7 by Molmil](/molmil-images/mine/7ud7) | Crystal structure of deoxygenated hemoglobin in complex with 5HMF-NO at 1.8 Angstrom | Descriptor: | Hemoglobin subunit alpha, Hemoglobin subunit beta, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Donkor, A.K, Musayev, F.N, Safo, M.K. | Deposit date: | 2022-03-18 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Design, Synthesis, and Antisickling Investigation of a Nitric Oxide-Releasing Prodrug of 5HMF for the Treatment of Sickle Cell Disease. Biomolecules, 12, 2022
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7UF6
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![BU of 7uf6 by Molmil](/molmil-images/mine/7uf6) | |
7UB4
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![BU of 7ub4 by Molmil](/molmil-images/mine/7ub4) | The crystal structure of the K36A/K38A/K233A/K234A quadruple mutant of E. coli YGGS in complex with PLP | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Pyridoxal phosphate homeostasis protein | Authors: | Donkor, A.K, Ghatge, M.S, Musayev, F.N, Safo, M.K. | Deposit date: | 2022-03-14 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Characterization of the Escherichia coli pyridoxal 5'-phosphate homeostasis protein (YggS): Role of lysine residues in PLP binding and protein stability. Protein Sci., 31, 2022
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7UD8
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![BU of 7ud8 by Molmil](/molmil-images/mine/7ud8) | Crystal structure of carbon monoxy Hemoglobin in complex with 5HMF at 1.8 Angstrom | Descriptor: | (5-methylfuran-2-yl)methanol, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | Authors: | Donkor, A.K, Musayev, F.N, Safo, M.S. | Deposit date: | 2022-03-18 | Release date: | 2022-03-30 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Design, Synthesis, and Antisickling Investigation of a Nitric Oxide-Releasing Prodrug of 5HMF for the Treatment of Sickle Cell Disease. Biomolecules, 12, 2022
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7UF7
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![BU of 7uf7 by Molmil](/molmil-images/mine/7uf7) | |
3IC2
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![BU of 3ic2 by Molmil](/molmil-images/mine/3ic2) | Crystal Structure of liganded hemoglobin in complex with a potent antisickling agent, INN-266 | Descriptor: | 4-[(5-methoxy-2-methylphenoxy)methyl]pyridine, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | Authors: | Safo, M.K, Musayev, F.N, Gandhi, A.K, Jorge, P. | Deposit date: | 2009-07-17 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural and in Vitro Chracterization of Pyridyl Derivatives of Benzaldehydes: Highly Potent Antisickling Agents To be Published
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3IC0
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![BU of 3ic0 by Molmil](/molmil-images/mine/3ic0) | Crystal Structure of liganded hemoglobin in complex with a potent antisickling agent, INN-298 | Descriptor: | 2-[(2-methoxy-5-methylphenoxy)methyl]pyridine, Hemoglobin subunit alpha, Hemoglobin subunit beta, ... | Authors: | Safo, M.K, Musayev, F.N, Gandhi, A.K, Jorge, P. | Deposit date: | 2009-07-17 | Release date: | 2009-07-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural and in Vitro Chracterization of Pridyl Derivatives of Benzaldehydes: Highly Potent Antisickling Agents To be Published
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