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PDB: 8 件

7K3C
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BU of 7k3c by Molmil
SGMGGIT segment 58-64 from Keratin-8
分子名称: ETHANOL, SGMGGIT segment 58-64 from the low complexity domain of Keratin-8, TRIETHYLENE GLYCOL
著者Murray, K.A, Sawaya, M.R, Eisenberg, D.S.
登録日2020-09-11
公開日2021-11-10
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies.
Nat.Struct.Mol.Biol., 29, 2022
7K3Y
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BU of 7k3y by Molmil
GGYAGAS segment 52-58 from Keratin-8
分子名称: GGYAGAS segment 52-58 from the low complexity domain of Keratin-8
著者Murray, K.A, Sawaya, M.R, Eisenberg, D.S.
登録日2020-09-14
公開日2021-11-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies.
Nat.Struct.Mol.Biol., 29, 2022
7K3X
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BU of 7k3x by Molmil
SGMGCIT segment 58-64 from Keratin-8 with G62C mutation
分子名称: ISOPROPYL ALCOHOL, SGMGCIT segment 58-64 from Keratin-8 with G62C mutation
著者Murray, K.A, Sawaya, M.R, Eisenberg, D.S.
登録日2020-09-14
公開日2021-11-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.705 Å)
主引用文献Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies.
Nat.Struct.Mol.Biol., 29, 2022
7UPE
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BU of 7upe by Molmil
Tau Paired Helical Filament from Alzheimer's Disease not incubated with EGCG
分子名称: Isoform Tau-F of Microtubule-associated protein tau
著者Seidler, P.M, Murray, K.A, Boyer, D.R, Ge, P, Sawaya, M.R, Eisenberg, D.S.
登録日2022-04-15
公開日2022-09-28
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro.
Nat Commun, 13, 2022
7UPF
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BU of 7upf by Molmil
Tau Paired Helical Filament from Alzheimer's Disease incubated 1 hr. with EGCG
分子名称: Isoform Tau-F of Microtubule-associated protein tau
著者Seidler, P.M, Murray, K.A, Boyer, D.R, Ge, P, Sawaya, M.R, Eisenberg, D.S.
登録日2022-04-15
公開日2022-09-28
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro.
Nat Commun, 13, 2022
7UPG
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BU of 7upg by Molmil
Tau Paired Helical Filament from Alzheimer's Disease incubated with EGCG for 3 hours
分子名称: (2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate, Isoform Tau-F of Microtubule-associated protein tau
著者Seidler, P.M, Murray, K.A, Boyer, D.R, Ge, P, Sawaya, M.R, Eisenberg, D.S.
登録日2022-04-15
公開日2022-09-28
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure-based discovery of small molecules that disaggregate Alzheimer's disease tissue derived tau fibrils in vitro.
Nat Commun, 13, 2022
6CU7
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BU of 6cu7 by Molmil
Alpha Synuclein fibril formed by full length protein - Rod Polymorph
分子名称: Alpha-synuclein
著者Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
6CU8
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BU of 6cu8 by Molmil
Alpha Synuclein fibril formed by full length protein - Twister Polymorph
分子名称: Alpha-synuclein
著者Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018

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件を2024-10-16に公開中

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