7WIJ
 
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8K3H
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8K3I
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4YL7
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4YZK
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4YZL
 | | Crystal structure of the indole prenyltransferase TleC complexed with indolactam V and DMSPP | | Descriptor: | (2S,5S)-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one, DIMETHYLALLYL S-THIOLODIPHOSPHATE, Tryptophan dimethylallyltransferase | | Authors: | Mori, T, Morita, H, Abe, I. | | Deposit date: | 2015-03-25 | | Release date: | 2016-03-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.096 Å) | | Cite: | Manipulation of prenylation reactions by structure-based engineering of bacterial indolactam prenyltransferases.
Nat Commun, 7, 2016
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4YLA
 | | Crystal structure of the indole prenyltransferase MpnD complexed with indolactam V and DMSPP | | Descriptor: | (2S,5S)-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one, Aromatic prenyltransferase, DIMETHYLALLYL S-THIOLODIPHOSPHATE, ... | | Authors: | Mori, T, Morita, H, Abe, I. | | Deposit date: | 2015-03-05 | | Release date: | 2016-03-16 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Manipulation of prenylation reactions by structure-based engineering of bacterial indolactam prenyltransferases.
Nat Commun, 7, 2016
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7BVR
 | | DgpB-DgpC complex apo | | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, AP_endonuc_2 domain-containing protein, DgpB, ... | | Authors: | Mori, T, He, H, Abe, I. | | Deposit date: | 2020-04-11 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes.
Nat Commun, 12, 2021
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7BVS
 | | DfgA-DfgB complex apo | | Descriptor: | DfgB, GLYCEROL, MANGANESE (II) ION, ... | | Authors: | Mori, T, He, H, Abe, I. | | Deposit date: | 2020-04-11 | | Release date: | 2021-04-14 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.85 Å) | | Cite: | C-Glycoside metabolism in the gut and in nature: Identification, characterization, structural analyses and distribution of C-C bond-cleaving enzymes.
Nat Commun, 12, 2021
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3WD7
 | | Type III polyketide synthase | | Descriptor: | COENZYME A, NICKEL (II) ION, SULFATE ION, ... | | Authors: | Mori, T, Shimokawa, Y, Matsui, T, Kato, R, Sugio, S, Morita, H, Abe, I. | | Deposit date: | 2013-06-10 | | Release date: | 2013-09-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Cloning, characterization, and crystal structure analysis of novel type III polyketide synthases from Citrus microcarpa
To be Published
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3WD8
 | | TypeIII polyketide synthases | | Descriptor: | GLYCEROL, Type III polyketide synthase quinolone synthase | | Authors: | Mori, T, Shimokawa, Y, Matsui, T, Morita, H, Abe, I. | | Deposit date: | 2013-06-10 | | Release date: | 2013-09-04 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.463 Å) | | Cite: | Cloning, characterization, and crystal structure analysis of novel type III polyketide synthases from Citrus microcarpa
To be Published
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3WXZ
 | | The structure of the I375F mutant of CsyB | | Descriptor: | Putative uncharacterized protein csyB | | Authors: | Mori, T, Yang, D, Matsui, T, Morita, H, Fujii, I, Abe, I. | | Deposit date: | 2014-08-13 | | Release date: | 2015-01-14 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.303 Å) | | Cite: | Structural basis for the formation of acylalkylpyrones from two beta-ketoacyl units by the fungal type III polyketide synthase CsyB.
J.Biol.Chem., 290, 2015
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5YJ0
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5YIZ
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5YJ1
 | | Mouse Cereblon thalidomide binding domain complexed with R-form thalidomide | | Descriptor: | 2-[(3~{R})-2,6-bis(oxidanylidene)piperidin-3-yl]isoindole-1,3-dione, Protein cereblon, SULFATE ION, ... | | Authors: | Mori, T, Hakoshima, T. | | Deposit date: | 2017-10-06 | | Release date: | 2018-02-07 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structural basis of thalidomide enantiomer binding to cereblon
Sci Rep, 8, 2018
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8IXP
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8IXQ
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7WPY
 | | AndA_M119A_N121V variant | | Descriptor: | Dioxygenase andA, FE (III) ION | | Authors: | Mori, T, Chen, H, Abe, I. | | Deposit date: | 2022-01-24 | | Release date: | 2023-02-01 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | AndA_M119A_N121V variant
To Be Published
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7ENB
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7EMZ
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2ZPY
 | | Crystal structure of the mouse radxin FERM domain complexed with the mouse CD44 cytoplasmic peptide | | Descriptor: | CD44 antigen, Radixin | | Authors: | Mori, T, Kitano, K, Terawaki, S, Maesaki, R, Fukami, Y, Hakoshima, T. | | Deposit date: | 2008-07-31 | | Release date: | 2008-08-26 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural basis for CD44 recognition by ERM proteins
J.Biol.Chem., 283, 2008
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3WX2
 | | Mouse Cereblon thalidomide binding domain, native | | Descriptor: | Protein cereblon, SULFATE ION, ZINC ION | | Authors: | Mori, T, Ito, T, Hirano, Y, Yamaguchi, Y, Handa, H, Hakoshima, T. | | Deposit date: | 2014-07-10 | | Release date: | 2014-08-06 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs
Nat.Struct.Mol.Biol., 21, 2014
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3WX1
 | | Mouse Cereblon thalidomide binding domain, selenomethionine derivative | | Descriptor: | Protein cereblon, SULFATE ION, ZINC ION | | Authors: | Mori, T, Ito, T, Hirano, Y, Yamaguchi, Y, Handa, H, Hakoshima, T. | | Deposit date: | 2014-07-10 | | Release date: | 2014-08-06 | | Last modified: | 2014-09-17 | | Method: | X-RAY DIFFRACTION (1.93 Å) | | Cite: | Structure of the human Cereblon-DDB1-lenalidomide complex reveals basis for responsiveness to thalidomide analogs
Nat.Struct.Mol.Biol., 21, 2014
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3WA0
 | | Crystal structure of merlin complexed with DCAF1/VprBP | | Descriptor: | Merlin, Protein VPRBP | | Authors: | Mori, T, Gotoh, S, Shirakawa, M, Hakoshima, T. | | Deposit date: | 2013-04-20 | | Release date: | 2014-05-28 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.31 Å) | | Cite: | Structural basis of DDB1-and-Cullin 4-associated Factor 1 (DCAF1) recognition by merlin/NF2 and its implication in tumorigenesis by CD44-mediated inhibition of merlin suppression of DCAF1 function.
Genes Cells, 19, 2014
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5XCV
 | | Crystal structure of NZ-1 Fv-clasp fragment with its antigen peptide | | Descriptor: | CALCIUM ION, PA14 peptide, VH(S112C)-SARAH chimera,VH(S112C)-SARAH chimera, ... | | Authors: | Arimori, T, Takagi, J. | | Deposit date: | 2017-03-23 | | Release date: | 2017-10-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.143 Å) | | Cite: | Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability
Structure, 25, 2017
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