4YLA

Crystal structure of the indole prenyltransferase MpnD complexed with indolactam V and DMSPP

Summary for 4YLA

• Entry DOI: 10.2210/pdb4yla/pdb
• Related: 4YL7
• Descriptor: Aromatic prenyltransferase, (2S,5S)-5-(hydroxymethyl)-1-methyl-2-(propan-2-yl)-1,2,4,5,6,8-hexahydro-3H-[1,4]diazonino[7,6,5-cd]indol-3-one, SULFATE ION, ... (5 entities in total)
• Functional Keywords: transferase, indole prenyltransferase, pt-fold, indolactam v
• Biological source: Marinactinospora thermotolerans
• Total number of polymer chains: 1
• Total formula weight: 41878.73

Authors

Mori, T.,Morita, H.,Abe, I. (deposition date: 2015-03-05, release date: 2016-03-16, Last modification date: 2023-11-08)

• Primary citation: Mori, T.,Zhang, L.,Awakawa, T.,Hoshino, S.,Okada, M.,Morita, H.,Abe, I.; Manipulation of prenylation reactions by structure-based engineering of bacterial indolactam prenyltransferases.; Nat Commun, 7:10849-10849, 2016; PubMed: 26952246; DOI: 10.1038/ncomms10849

Experimental method

X-RAY DIFFRACTION (1.4 Å)