5YJ1
Mouse Cereblon thalidomide binding domain complexed with R-form thalidomide
Summary for 5YJ1
Entry DOI | 10.2210/pdb5yj1/pdb |
Related | 3WX2 5YIZ 5YJ0 |
Descriptor | Protein cereblon, 2-[(3~{R})-2,6-bis(oxidanylidene)piperidin-3-yl]isoindole-1,3-dione, ZINC ION, ... (5 entities in total) |
Functional Keywords | zinc binding protein, metal binding protein |
Biological source | Mus musculus (Mouse) |
Cellular location | Cytoplasm : Q8C7D2 |
Total number of polymer chains | 16 |
Total formula weight | 205424.43 |
Authors | Mori, T.,Hakoshima, T. (deposition date: 2017-10-06, release date: 2018-02-07, Last modification date: 2023-11-22) |
Primary citation | Mori, T.,Ito, T.,Liu, S.,Ando, H.,Sakamoto, S.,Yamaguchi, Y.,Tokunaga, E.,Shibata, N.,Handa, H.,Hakoshima, T. Structural basis of thalidomide enantiomer binding to cereblon Sci Rep, 8:1294-1294, 2018 Cited by PubMed: 29358579DOI: 10.1038/s41598-018-19202-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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