5YJ1
Mouse Cereblon thalidomide binding domain complexed with R-form thalidomide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, D, G, J, M...) | Protein cereblon | polymer | 111 | 12335.3 | 16 | UniProt (Q8C7D2) Pfam (PF03226) | Mus musculus (Mouse) | Protein PiL |
| 2 | AA, DB, EA, HB, JA... (J, e, M, h, P...) | 2-[(3~{R})-2,6-bis(oxidanylidene)piperidin-3-yl]isoindole-1,3-dione | non-polymer | 258.2 | 16 | Chemie (6EL) | |||
| 3 | AB, BA, EB, FA, IB... (b, J, e, M, h...) | ZINC ION | non-polymer | 65.4 | 16 | Chemie (ZN) | |||
| 4 | BB, CA, CB, DA, FB... (b, J, e, M, h...) | SULFATE ION | non-polymer | 96.1 | 30 | Chemie (SO4) | |||
| 5 | AC, BC, CC, DC, EC... (A, D, G, J, M...) | water | water | 18.0 | 786 | Chemie (HOH) |
Sequence modifications
A, D, G, J, M, P, S, V, Y, b, e, h, k, n, q, t: 322 - 430 (UniProt: Q8C7D2)
| PDB | External Database | Details |
|---|---|---|
| Gly 320 | - | expression tag |
| Pro 321 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 16 |
| Total formula weight | 197364.3 | |
| Non-Polymers* | Number of molecules | 62 |
| Total formula weight | 8060.1 | |
| All* | Total formula weight | 205424.4 |
