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PDB: 43 件
8FHI
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Wildtype rabbit TRPV5 in nanodiscs in complex with oleoyl coenzyme A, Open stated
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL, S-{(3R,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (9Z)-octadec-9-enethioate (non-preferred name), ...
著者De Jesus-Perez, J.J, Moiseenkova-Bell, V.Y.
登録日2022-12-14
公開日2023-11-01
実験手法ELECTRON MICROSCOPY (3.25 Å)
主引用文献Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A.
Nat Commun, 14, 2023
8FHH
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Wildtype rabbit TRPV5 in nanodiscs in the presence of oleoyl coenzyme A, Closed stated
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5
著者De Jesus-Perez, J.J, Moiseenkova-Bell, V.Y.
登録日2022-12-14
公開日2023-11-01
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural basis of the activation of TRPV5 channels by long-chain acyl-Coenzyme-A.
Nat Commun, 14, 2023
8FFQ
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Wildtype rabbit TRPV5 into nanodiscs in the presence of PI(4,5)P2 and ruthenium red
分子名称: 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5, ...
著者De Jesus-Perez, J.J, Fluck, E.C, Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, Moiseenkova-Bell, V.Y.
登録日2022-12-09
公開日2024-02-07
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (2.65 Å)
主引用文献Molecular details of ruthenium red pore block in TRPV channels.
Embo Rep., 25, 2024
8FFM
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BU of 8ffm by Molmil
Wildtype rat TRPV2 in nanodiscs bound to RR and 2-APB
分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 2, ...
著者Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y.
登録日2022-12-09
公開日2024-02-07
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Molecular details of ruthenium red pore block in TRPV channels.
Embo Rep., 25, 2024
8FFL
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BU of 8ffl by Molmil
Wildtype rat TRPV2 in nanodiscs bound to RR
分子名称: 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, Transient receptor potential cation channel subfamily V member 2
著者Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, De Jesus-Perez, J.J, Fluck, E.C, Moiseenkova-Bell, V.Y.
登録日2022-12-09
公開日2024-02-07
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Molecular details of ruthenium red pore block in TRPV channels.
Embo Rep., 25, 2024
8FFN
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RR-bound wildtype rabbit TRPV5 in nanodiscs
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, ERGOSTEROL, Transient receptor potential cation channel subfamily V member 5, ...
著者Fluck, E.C, De Jesus-Perez, J.J, Pumroy, R.A, Protopopova, A.D, Rocereta, J.A, Moiseenkova-Bell, V.Y.
登録日2022-12-09
公開日2024-02-07
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (2.96 Å)
主引用文献Molecular details of ruthenium red pore block in TRPV channels.
Embo Rep., 25, 2024
7T37
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Activated state of 2-APB and CBD-bound wildtype rat TRPV2 in nanodiscs
分子名称: 2-aminoethyl diphenylborinate, Transient receptor potential cation channel subfamily V member 2, cannabidiol
著者Pumroy, R.A, Protopopova, A.D, Gallo, P.N, Moiseenkova-Bell, V.Y.
登録日2021-12-07
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural insights into TRPV2 activation by small molecules.
Nat Commun, 13, 2022
7T38
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Inactivated state of 2-APB and CBD-bound wildtype rat TRPV2 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 2
著者Pumroy, R.A, Protopopova, A.D, Gallo, P.N, Moiseenkova-Bell, V.Y.
登録日2021-12-07
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural insights into TRPV2 activation by small molecules.
Nat Commun, 13, 2022
7T6J
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Cryo-EM structure of TRPV5 at pH8 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6K
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BU of 7t6k by Molmil
Cryo-EM structure of TRPV5 at pH6 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6R
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BU of 7t6r by Molmil
Cryo-EM structure of TRPV5 T709D in nanodiscs in the presence of Calmodulin
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6M
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BU of 7t6m by Molmil
Cryo-EM structure of TRPV5 in nanodiscs with PI(4,5)P2 at pH6 state 1
分子名称: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6L
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BU of 7t6l by Molmil
Cryo-EM structure of TRPV5 at pH5 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6Q
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BU of 7t6q by Molmil
Cryo-EM structure of TRPV5 T709D with PI(4,5)P2 in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6P
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BU of 7t6p by Molmil
Cryo-EM structure of TRPV5 T709D in nanodiscs
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6O
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BU of 7t6o by Molmil
Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 3
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
7T6N
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BU of 7t6n by Molmil
Cryo-EM structure of TRPV5 in nanodiscs at pH6 state 2
分子名称: Transient receptor potential cation channel subfamily V member 5
著者Fluck, E.C, Yazici, A.T, Rohacs, T, Moiseenkova-Bell, V.Y.
登録日2021-12-14
公開日2022-05-04
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of TRPV5 regulation by physiological and pathophysiological modulators.
Cell Rep, 39, 2022
8G8W
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BU of 8g8w by Molmil
Molecular mechanism of nucleotide inhibition of human uncoupling protein 1
分子名称: CARDIOLIPIN, GUANOSINE-5'-TRIPHOSPHATE, Mitochondrial brown fat uncoupling protein 1, ...
著者Gogoi, P, Jones, S.A, Ruprecht, J.J, King, M.S, Lee, Y, Zogg, T, Pardon, E, Chand, D, Steimle, S, Copeman, D, Cotrim, C.A, Steyaert, J, Crichton, P.G, Moiseenkova-Bell, V, Kunji, E.R.S.
登録日2023-02-20
公開日2023-06-07
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of purine nucleotide inhibition of human uncoupling protein 1.
Sci Adv, 9, 2023
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