8FFM

Wildtype rat TRPV2 in nanodiscs bound to RR and 2-APB

Summary for 8FFM

Entry DOI	10.2210/pdb8ffm/pdb
EMDB information	29047
Descriptor	Transient receptor potential cation channel subfamily V member 2, 1,2-DIDECANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-aminoethyl diphenylborinate, ... (4 entities in total)
Functional Keywords	trpv2, 2-apb, trp channel, ruthenium red, membrane protein
Biological source	Rattus norvegicus (Norway rat)
Total number of polymer chains	4
Total formula weight	350745.99
Authors	Pumroy, R.A.,Protopopova, A.D.,Rocereta, J.A.,De Jesus-Perez, J.J.,Fluck, E.C.,Moiseenkova-Bell, V.Y. (deposition date: 2022-12-09, release date: 2024-02-07, Last modification date: 2024-02-21)
Primary citation	Pumroy, R.A.,De Jesus-Perez, J.J.,Protopopova, A.D.,Rocereta, J.A.,Fluck, E.C.,Fricke, T.,Lee, B.H.,Rohacs, T.,Leffler, A.,Moiseenkova-Bell, V. Molecular details of ruthenium red pore block in TRPV channels. Embo Rep., 25:506-523, 2024 Cited by PubMed: 38225355 DOI: 10.1038/s44319-023-00050-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation