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PDB: 15 件
3EU0
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Crystal structure of the S-nitrosylated Cys215 of PTP1B
分子名称: Tyrosine-protein phosphatase non-receptor type 1
著者Chu, H.M, Wang, A.H.J, Chen, Y.Y, Pan, K.T, Wang, D.L, Khoo, K.H, Meng, T.C.
登録日2008-10-09
公開日2008-11-11
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Cysteine S-Nitrosylation Protects Protein-tyrosine Phosphatase 1B against Oxidation-induced Permanent Inactivation
J.Biol.Chem., 283, 2008
4S0G
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Crystal structure of PTPN3 (PTPH1) in complex with Eps15 pTyr849 P850V peptide
分子名称: Peptide from Epidermal growth factor receptor substrate 15, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.-E, Meng, T.C, Wang, A.H.-J.
登録日2014-12-31
公開日2015-03-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.723 Å)
主引用文献Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Structure, 23, 2015
4RH5
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Crystal structure of PTPN3 (PTPH1) in complex with Eps15 pTyr849 peptide
分子名称: Epidermal growth factor receptor substrate 15, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.-E, Meng, T.C, Wang, A.H.-J.
登録日2014-10-01
公開日2015-03-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Structure, 23, 2015
4QUN
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Crystal structure of the PTPN3 (PTPH1) catalytic domain C842S mutant
分子名称: GLYCEROL, PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.E, Meng, T.C, Wang, A.H.J.
登録日2014-07-11
公開日2014-12-10
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Reciprocal allosteric regulation of p38 gamma and PTPN3 involves a PDZ domain-modulated complex formation.
Sci.Signal., 7, 2014
4QUM
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Crystal structure of PTPN3 (PTPH1) in complex with a dually phosphorylated MAPK12 peptide
分子名称: Mitogen-activated protein kinase 12, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.E, Meng, T.C, Wang, A.H.J.
登録日2014-07-10
公開日2014-12-10
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.516 Å)
主引用文献Reciprocal allosteric regulation of p38 gamma and PTPN3 involves a PDZ domain-modulated complex formation.
Sci.Signal., 7, 2014
4RH9
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Crystal structure of PTPN3 (PTPH1) H812F, M883G mutant in complex with Eps15 pTyr849 peptide
分子名称: Epidermal growth factor receptor substrate 15, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.-E, Meng, T.C, Wang, A.H.-J.
登録日2014-10-01
公開日2015-03-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.598 Å)
主引用文献Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Structure, 23, 2015
4RHG
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Crystal structure of PTPN3 (PTPH1) D811E, C842S mutant in complex with Eps15 pTyr849 peptide
分子名称: Epidermal growth factor receptor substrate 15, Tyrosine-protein phosphatase non-receptor type 3
著者Chen, K.-E, Meng, T.C, Wang, A.H.-J.
登録日2014-10-02
公開日2015-03-11
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.581 Å)
主引用文献Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Structure, 23, 2015
4RI4
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Crystal structure of PTPN3 (PTPH1) Y676I mutant in complex with vanadate
分子名称: Tyrosine-protein phosphatase non-receptor type 3, VANADATE ION
著者Chen, K.-E, Meng, T.C, Wang, A.H.-J.
登録日2014-10-05
公開日2015-03-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.596 Å)
主引用文献Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Structure, 23, 2015
4RI5
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Crystal structure of PTPN3 (PTPH1) D811E mutant in complex with metavanadate
分子名称: GLYCEROL, Tyrosine-protein phosphatase non-receptor type 3, oxido(dioxo)vanadium
著者Chen, K.-E, Meng, T.C, Wang, A.H.-J.
登録日2014-10-05
公開日2015-03-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.26 Å)
主引用文献Substrate specificity and plasticity of FERM-containing protein tyrosine phosphatases.
Structure, 23, 2015
1OEM
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PTP1B with the catalytic cysteine oxidized to a sulfenyl-amide bond
分子名称: PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1
著者Salmeen, A, Andersen, J.N, Myers, M.P, Meng, T.C, Hinks, J.A, Tonks, N.K, Barford, D.
登録日2003-03-28
公開日2003-06-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Redox Regulation of Protein Tyrosine Phosphatase Involves a Sulfenyl-Amide Intermediate
Nature, 423, 2003
1OEO
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PTP1B with the catalytic cysteine oxidized to sulfonic acid
分子名称: PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1
著者Salmeen, A, Andersen, J.N, Myers, M.P, Meng, T.C, Hinks, J.A, Tonks, N.K, Barford, D.
登録日2003-03-28
公開日2003-06-12
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Redox Regulation of Protein Tyrosine Phosphatase Involves a Sulfenyl-Amide Intermediate
Nature, 423, 2003
7F5N
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Crystal structure of TCPTP catalytic domain
分子名称: Tyrosine-protein phosphatase non-receptor type 2
著者Singh, J.P, Lin, M.-J, Hsu, S.-F, Lee, C.-C, Meng, T.-C.
登録日2021-06-22
公開日2021-12-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal Structure of TCPTP Unravels an Allosteric Regulatory Role of Helix alpha 7 in Phosphatase Activity.
Biochemistry, 60, 2021
7F5O
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Crystal structure of PTPN2 catalytic domain
分子名称: IODIDE ION, Tyrosine-protein phosphatase non-receptor type 2
著者Singh, J.P, Lin, M.-J, Hsu, S.-F, Lee, C.-C, Meng, T.-C.
登録日2021-06-22
公開日2021-12-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of TCPTP Unravels an Allosteric Regulatory Role of Helix alpha 7 in Phosphatase Activity.
Biochemistry, 60, 2021
5ZXH
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BU of 5zxh by Molmil
The structure of MT189-tubulin complex
分子名称: 2-(6-fluoro-3-{[(4-methoxyphenyl)methyl]amino}imidazo[1,2-a]pyridin-2-yl)phenol, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ...
著者Li, Z.P, Wang, Y.X, Meng, T, Yang, J.L, Chen, Q.
登録日2018-05-21
公開日2019-05-22
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of MT189-Tubulin Complex Provides Insights into Drug Design
Lett.Drug Des.Discovery, 2019
7CGA
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Crystal structure of human unphosphorylated p38gamma
分子名称: Mitogen-activated protein kinase 12
著者Lee, C.C, Hsu, S.F, Chen, K.E, Wang, A.H.J, Meng, T.C.
登録日2020-06-30
公開日2021-06-30
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural basis for allosteric regulation of protein tyrosine phosphatase PTPN3 by unphosphorylated MAP kinase p38g
To be published

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件を2024-07-24に公開中

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