5XGZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5xgz by Molmil](/molmil-images/mine/5xgz) | Metagenomic glucose-tolerant glycosidase | Descriptor: | Beta-glycosidase, GLYCEROL, NICKEL (II) ION, ... | Authors: | Watanabe, M, Matsuzawa, T, Yaoi, K. | Deposit date: | 2017-04-19 | Release date: | 2018-05-02 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Improved thermostability of a metagenomic glucose-tolerant beta-glycosidase based on its X-ray crystal structure. Appl.Microbiol.Biotechnol., 101, 2017
|
|
1UEX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1uex by Molmil](/molmil-images/mine/1uex) | Crystal structure of von Willebrand Factor A1 domain complexed with snake venom bitiscetin | Descriptor: | bitiscetin alpha chain, bitiscetin beta chain, von Willebrand Factor | Authors: | Maita, N, Nishio, K, Nishimoto, E, Matsui, T, Shikamoto, Y, Morita, T, Sadler, J.E, Mizuno, H. | Deposit date: | 2003-05-22 | Release date: | 2003-09-30 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Crystal structure of von Willebrand factor A1 domain complexed with snake venom, bitiscetin. Insight into glycoprotein Ibalpha binding mechanism induced by snake venom proteins. J.Biol.Chem., 278, 2003
|
|
7FEH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7feh by Molmil](/molmil-images/mine/7feh) | Crystal structure of human DDR1 in complex with CH5541127 | Descriptor: | Epithelial discoidin domain-containing receptor 1, N-[(5-chloranyl-2-ethylsulfonyl-phenyl)methyl]-3-piperazin-1-yl-5-(trifluoromethyloxy)benzamide, NITRATE ION | Authors: | Fukami, T.A, Kadono, S, Matsuura, T. | Deposit date: | 2021-07-20 | Release date: | 2022-07-27 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Novel potent and highly selective DDR1 inhibitors from integrated lead finding Medicinal Chemistry Research, 32, 2023
|
|
1V8X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1v8x by Molmil](/molmil-images/mine/1v8x) | Crystal Structure of the Dioxygen-bound Heme Oxygenase from Corynebacterium diphtheriae | Descriptor: | Heme oxygenase, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Unno, M, Matsui, T, Chu, G.C, Couture, M, Yoshida, T, Rousseau, D.L, Olson, J.S, Ikeda-Saito, M. | Deposit date: | 2004-01-15 | Release date: | 2004-05-18 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal Structure of the Dioxygen-bound Heme Oxygenase from Corynebacterium diphtheriae: IMPLICATIONS FOR HEME OXYGENASE FUNCTION. J.Biol.Chem., 279, 2004
|
|
2D4F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2d4f by Molmil](/molmil-images/mine/2d4f) | The Crystal Structure of human beta2-microglobulin | Descriptor: | Beta-2-microglobulin, SODIUM ION | Authors: | Iwata, K, Matsuura, T, Nakagawa, A, Goto, Y. | Deposit date: | 2005-10-18 | Release date: | 2006-08-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Conformation of Amyloid Fibrils of beta2-Microglobulin Probed by Tryptophan Mutagenesis J.Biol.Chem., 281, 2006
|
|
2DFV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2dfv by Molmil](/molmil-images/mine/2dfv) | Hyperthermophilic threonine dehydrogenase from Pyrococcus horikoshii | Descriptor: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, Probable L-threonine 3-dehydrogenase, SULFATE ION, ... | Authors: | Ishikawa, K, Higashi, N, Nakamura, T, Matsuura, T, Nakagawa, A. | Deposit date: | 2006-03-03 | Release date: | 2007-01-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The first crystal structure of L-threonine dehydrogenase. J.Mol.Biol., 366, 2007
|
|
1UC9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1uc9 by Molmil](/molmil-images/mine/1uc9) | Crystal structure of a lysine biosynthesis enzyme, Lysx, from thermus thermophilus HB8 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, lysine biosynthesis enzyme | Authors: | Sakai, H, Vassylyeva, M.N, Matsuura, T, Sekine, S, Nishiyama, M, Terada, T, Shirouzu, M, Kuramitsu, S, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-04-09 | Release date: | 2003-09-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.38 Å) | Cite: | Crystal Structure of a Lysine Biosynthesis Enzyme, LysX, from Thermus thermophilus HB8 J.Mol.Biol., 332, 2003
|
|
1UC8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1uc8 by Molmil](/molmil-images/mine/1uc8) | Crystal structure of a lysine biosynthesis enzyme, Lysx, from thermus thermophilus HB8 | Descriptor: | lysine biosynthesis enzyme | Authors: | Sakai, H, Vassylyeva, M.N, Matsuura, T, Sekine, S, Nishiyama, M, Terada, T, Shirouzu, M, Kuramitsu, S, Vassylyev, D.G, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2003-04-09 | Release date: | 2003-09-23 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of a Lysine Biosynthesis Enzyme, LysX, from Thermus thermophilus HB8 J.Mol.Biol., 332, 2003
|
|
7E7F
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7e7f by Molmil](/molmil-images/mine/7e7f) | Human CYP11B1 mutant in complex with metyrapone | Descriptor: | CHOLIC ACID, Cytochrome P450 11B1, mitochondrial, ... | Authors: | Mukai, K, Sugimoto, H, Reiko, S, Matsuura, T, Hishiki, T, Kagawa, N. | Deposit date: | 2021-02-26 | Release date: | 2022-01-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Spatially restricted substrate-binding site of cortisol-synthesizing CYP11B1 limits multiple hydroxylations and hinders aldosterone synthesis. Curr Res Struct Biol, 3, 2021
|
|
3FUC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fuc by Molmil](/molmil-images/mine/3fuc) | Recombinant calf purine nucleoside phosphorylase in a binary complex with multisubstrate analogue inhibitor 9-(5',5'-difluoro-5'-phosphonopentyl)-9-deazaguanine structure in a new space group with one full trimer in the asymmetric unit | Descriptor: | AZIDE ION, MAGNESIUM ION, Purine nucleoside phosphorylase, ... | Authors: | Bochtler, M, Breer, K, Bzowska, A, Chojnowski, G, Hashimoto, M, Hikishima, S, Narczyk, M, Wielgus-Kutrowska, B, Yokomatsu, T. | Deposit date: | 2009-01-14 | Release date: | 2009-12-08 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | 1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state. Biochem.Biophys.Res.Commun., 391, 2010
|
|
7EQE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7eqe by Molmil](/molmil-images/mine/7eqe) | Crystal Structure of a transcription factor | Descriptor: | TetR/AcrR family transcriptional regulator | Authors: | Uehara, S, Tsugita, A, Matsui, T, Yokoyama, T, Ostash, I, Ostash, B, Tanaka, Y. | Deposit date: | 2021-05-01 | Release date: | 2022-04-27 | Last modified: | 2022-10-19 | Method: | X-RAY DIFFRACTION (2.399 Å) | Cite: | The carbohydrate tail of landomycin A is responsible for its interaction with the repressor protein LanK. Febs J., 289, 2022
|
|
7EQF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7eqf by Molmil](/molmil-images/mine/7eqf) | Crystal Structure of a Transcription Factor in complex with Ligand | Descriptor: | (6~{R})-3-methyl-8-[(2~{S},4~{R},5~{S},6~{R})-6-methyl-5-[(2~{S},4~{R},5~{R},6~{R})-6-methyl-4-[(2~{S},5~{S},6~{S})-6-methyl-5-[(2~{S},4~{R},5~{S},6~{R})-6-methyl-5-[(2~{S},4~{S},5~{S},6~{R})-6-methyl-4-[(2~{S},5~{S},6~{S})-6-methyl-5-oxidanyl-oxan-2-yl]oxy-5-oxidanyl-oxan-2-yl]oxy-4-oxidanyl-oxan-2-yl]oxy-oxan-2-yl]oxy-5-oxidanyl-oxan-2-yl]oxy-4-oxidanyl-oxan-2-yl]oxy-1,6,11-tris(oxidanyl)-5,6-dihydrobenzo[a]anthracene-7,12-dione, TetR/AcrR family transcriptional regulator | Authors: | Uehara, S, Tsugita, A, Matsui, T, Yokoyama, T, Ostash, I, Ostash, B, Tanaka, Y. | Deposit date: | 2021-05-01 | Release date: | 2022-04-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | The carbohydrate tail of landomycin A is responsible for its interaction with the repressor protein LanK. Febs J., 289, 2022
|
|
5YQS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5yqs by Molmil](/molmil-images/mine/5yqs) | Isoprimeverose-producing enzyme from Aspergillus oryzae in complex with isoprimeverose | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Yaoi, K, Matsuzawa, T, Watanabe, M, Nakamichi, Y. | Deposit date: | 2017-11-07 | Release date: | 2018-11-14 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure and substrate recognition mechanism of Aspergillus oryzae isoprimeverose-producing enzyme. J.Struct.Biol., 205, 2019
|
|
3EMS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ems by Molmil](/molmil-images/mine/3ems) | Effect of Ariginine on lysozyme | Descriptor: | ARGININE, CHLORIDE ION, Lysozyme C, ... | Authors: | Ito, L, Shiraki, K, Matsuura, T, Yamaguhi, H. | Deposit date: | 2008-09-25 | Release date: | 2008-10-21 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.651 Å) | Cite: | Effect of Ariginine on lysozyme to be published
|
|
1DIO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dio by Molmil](/molmil-images/mine/1dio) | DIOL DEHYDRATASE-CYANOCOBALAMIN COMPLEX FROM KLEBSIELLA OXYTOCA | Descriptor: | COBALAMIN, POTASSIUM ION, PROTEIN (DIOL DEHYDRATASE), ... | Authors: | Shibata, N, Masuda, J, Tobimatsu, T, Toraya, T, Suto, K, Morimoto, Y, Yasuoka, N. | Deposit date: | 1999-01-27 | Release date: | 2000-01-30 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | A new mode of B12 binding and the direct participation of a potassium ion in enzyme catalysis: X-ray structure of diol dehydratase. Structure Fold.Des., 7, 1999
|
|
1WNW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wnw by Molmil](/molmil-images/mine/1wnw) | D136N mutant of Heme Oxygenase from Corynebacterium diphtheriae (HmuO) | Descriptor: | Heme oxygenase, IODIDE ION, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Unno, M, Matsui, T, Ikeda-Saito, M. | Deposit date: | 2004-08-10 | Release date: | 2004-11-09 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Roles of Distal Asp in Heme Oxygenase from Corynebacterium diphtheriae, HmuO: A WATER-DRIVEN OXYGEN ACTIVATION MECHANISM J.Biol.Chem., 280, 2005
|
|
1X1N
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1x1n by Molmil](/molmil-images/mine/1x1n) | Structure determination and refinement at 1.8 A resolution of Disproportionating Enzyme from Potato | Descriptor: | 4-alpha-glucanotransferase, CALCIUM ION, GLYCEROL | Authors: | Imamura, K, Matsuura, T, Takaha, T, Fujii, K, Nakagawa, A, Kusunoki, M, Nitta, Y. | Deposit date: | 2005-04-08 | Release date: | 2006-04-18 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure determination and refinement at 1.8 A resolution of Disproportionating Enzyme from Potato to be published
|
|
1WD7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wd7 by Molmil](/molmil-images/mine/1wd7) | Crystal Structure of Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (Wild type, Native, Form-2 crystal) | Descriptor: | Uroporphyrinogen III Synthase | Authors: | Mizohata, E, Matsuura, T, Sakai, H, Murayama, K, Terada, T, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-12 | Release date: | 2004-11-12 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal Structure of Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (Wild type, Native, Form-2 crystal) to be published
|
|
2ZWB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zwb by Molmil](/molmil-images/mine/2zwb) | Neutron crystal structure of wild type human lysozyme in D2O | Descriptor: | Lysozyme C | Authors: | Chiba-Kamoshida, K, Matsui, T, Chatake, T, Ohhara, T, Ostermann, A, Tanaka, I, Yutani, K, Niimura, N. | Deposit date: | 2008-12-02 | Release date: | 2009-12-08 | Last modified: | 2023-11-01 | Method: | NEUTRON DIFFRACTION (1.8 Å) | Cite: | Site-specific softening of peptide bonds by localized deuterium observed by neutron crystallography of human lysozyme To be Published
|
|
1WCX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wcx by Molmil](/molmil-images/mine/1wcx) | Crystal Structure of Mutant Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (L75M/I193M/L248M, SeMet derivative, Form-1 crystal) | Descriptor: | GLYCEROL, Uroporphyrinogen III Synthase | Authors: | Mizohata, E, Matsuura, T, Murayama, K, Sakai, H, Terada, T, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-06 | Release date: | 2005-05-06 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of Uroporphyrinogen III Synthase from Thermus thermophilus HB8 To be Published
|
|
1WCW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wcw by Molmil](/molmil-images/mine/1wcw) | Crystal Structure of Uroporphyrinogen III Synthase from an Extremely Thermophilic Bacterium Thermus thermophilus HB8 (Wild type, Native, Form-1 crystal) | Descriptor: | GLYCEROL, Uroporphyrinogen III synthase | Authors: | Mizohata, E, Matsuura, T, Sakai, H, Murayama, K, Terada, T, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2004-05-06 | Release date: | 2005-05-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Crystal Structure of Uroporphyrinogen III Synthase from Thermus thermophilus HB8 To be Published
|
|
1O9X
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1o9x by Molmil](/molmil-images/mine/1o9x) | HUMAN SERUM ALBUMIN COMPLEXED WITH TETRADECANOIC ACID (MYRISTIC ACID) AND HEMIN | Descriptor: | MYRISTIC ACID, PROTOPORPHYRIN IX CONTAINING FE, SERUM ALBUMIN | Authors: | Zunszain, P.A, Ghuman, J, Komatsu, T, Tsuchida, E, Curry, S. | Deposit date: | 2002-12-20 | Release date: | 2003-03-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Crystal Structure Analysis of Human Serum Albumin Complexed with Hemin and Fatty Acid Bmc Struct.Biol., 3, 2003
|
|
3AUJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3auj by Molmil](/molmil-images/mine/3auj) | Structure of diol dehydratase complexed with glycerol | Descriptor: | CALCIUM ION, COBALAMIN, Diol dehydrase alpha subunit, ... | Authors: | Yamanishi, M, Kinoshita, K, Fukuoka, M, Shibata, T, Tobimatsu, T, Toraya, T. | Deposit date: | 2011-02-07 | Release date: | 2012-02-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Redesign of coenzyme B(12) dependent diol dehydratase to be resistant to the mechanism-based inactivation by glycerol and act on longer chain 1,2-diols Febs J., 279, 2012
|
|
2ZDY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2zdy by Molmil](/molmil-images/mine/2zdy) | Inhibitor-bound structures of human pyruvate dehydrogenase kinase 4 | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Kawamoto, M, Shiromizu, I, Kukimoto-Niino, M, Tokmakov, A, Terada, T, Shirouzu, M, Matsusue, T, Yokoyama, S. | Deposit date: | 2007-12-01 | Release date: | 2008-12-09 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Inhibitor-bound structures of human pyruvate dehydrogenase kinase 4. Acta Crystallogr.,Sect.D, 67, 2011
|
|
1WNX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1wnx by Molmil](/molmil-images/mine/1wnx) | D136E mutant of Heme Oxygenase from Corynebacterium diphtheriae (HmuO) | Descriptor: | Heme oxygenase, PROTOPORPHYRIN IX CONTAINING FE, SODIUM ION, ... | Authors: | Unno, M, Matsui, T, Ikeda-Saito, M. | Deposit date: | 2004-08-10 | Release date: | 2004-11-09 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Roles of Distal Asp in Heme Oxygenase from Corynebacterium diphtheriae, HmuO: A WATER-DRIVEN OXYGEN ACTIVATION MECHANISM J.Biol.Chem., 280, 2005
|
|