7EQF
Crystal Structure of a Transcription Factor in complex with Ligand
Summary for 7EQF
Entry DOI | 10.2210/pdb7eqf/pdb |
Related | 7EQE |
Descriptor | TetR/AcrR family transcriptional regulator, (6~{R})-3-methyl-8-[(2~{S},4~{R},5~{S},6~{R})-6-methyl-5-[(2~{S},4~{R},5~{R},6~{R})-6-methyl-4-[(2~{S},5~{S},6~{S})-6-methyl-5-[(2~{S},4~{R},5~{S},6~{R})-6-methyl-5-[(2~{S},4~{S},5~{S},6~{R})-6-methyl-4-[(2~{S},5~{S},6~{S})-6-methyl-5-oxidanyl-oxan-2-yl]oxy-5-oxidanyl-oxan-2-yl]oxy-4-oxidanyl-oxan-2-yl]oxy-oxan-2-yl]oxy-5-oxidanyl-oxan-2-yl]oxy-4-oxidanyl-oxan-2-yl]oxy-1,6,11-tris(oxidanyl)-5,6-dihydrobenzo[a]anthracene-7,12-dione (2 entities in total) |
Functional Keywords | transcription factor, transcription |
Biological source | Streptomyces griseoluteus |
Total number of polymer chains | 4 |
Total formula weight | 92603.19 |
Authors | Uehara, S.,Tsugita, A.,Matsui, T.,Yokoyama, T.,Ostash, I.,Ostash, B.,Tanaka, Y. (deposition date: 2021-05-01, release date: 2022-04-27, Last modification date: 2023-11-29) |
Primary citation | Tsugita, A.,Uehara, S.,Matsui, T.,Yokoyama, T.,Ostash, I.,Deneka, M.,Yalamanchili, S.,Bennett, C.S.,Tanaka, Y.,Ostash, B. The carbohydrate tail of landomycin A is responsible for its interaction with the repressor protein LanK. Febs J., 289:6038-6057, 2022 Cited by PubMed: 35429224DOI: 10.1111/febs.16460 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.91 Å) |
Structure validation
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