7EQF

Crystal Structure of a Transcription Factor in complex with Ligand

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	TetR/AcrR family transcriptional regulator	polymer	200	22335.4	4	UniProt (A0A4Z1DIH6) Pfam (PF00440)	Streptomyces griseoluteus
2	E, F, G (A, C, D)	(6~{R})-3-methyl-8-[(2~{S},4~{R},5~{S},6~{R})-6-methyl-5-[(2~{S},4~{R},5~{R},6~{R})-6-methyl-4-[(2~{S},5~{S},6~{S})-6-methyl-5-[(2~{S},4~{R},5~{S},6~{R})-6-methyl-5-[(2~{S},4~{S},5~{S},6~{R})-6-methyl-4-[(2~{S},5~{S},6~{S})-6-methyl-5-oxidanyl-oxan-2-yl]oxy-5-oxidanyl-oxan-2-yl]oxy-4-oxidanyl-oxan-2-yl]oxy-oxan-2-yl]oxy-5-oxidanyl-oxan-2-yl]oxy-4-oxidanyl-oxan-2-yl]oxy-1,6,11-tris(oxidanyl)-5,6-dihydrobenzo[a]anthracene-7,12-dione	non-polymer		1087.2	3	Chemie (JB0)

Sequence modifications

A, B, C, D: 1 - 192 (UniProt: A0A4Z1DIH6)

PDB	External Database	Details
Mse -7	-	initiating methionine
Gly -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Thr 83	Asn 83	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	89341.7
Non-Polymers*	Number of molecules	3
	Total formula weight	3261.5
All*	Total formula weight	92603.2

*Water molecules are not included.