5ICW
 
 | | Crystal structure of human NatF (hNaa60) homodimer bound to Coenzyme A | | Descriptor: | CHLORIDE ION, COENZYME A, N-alpha-acetyltransferase 60 | | Authors: | Stove, S.I, Magin, R.S, Marmorstein, R, Arnesen, T. | | Deposit date: | 2016-02-23 | | Release date: | 2016-06-22 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.951 Å) | | Cite: | Crystal Structure of the Golgi-Associated Human N alpha-Acetyltransferase 60 Reveals the Molecular Determinants for Substrate-Specific Acetylation.
Structure, 24, 2016
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6POF
 | | Structure of human ATP citrate lyase | | Descriptor: | ATP-citrate synthase | | Authors: | Wei, X, Marmorstein, R. | | Deposit date: | 2019-07-03 | | Release date: | 2020-01-01 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (4.3 Å) | | Cite: | Molecular basis for acetyl-CoA production by ATP-citrate lyase.
Nat.Struct.Mol.Biol., 27, 2020
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6PPL
 | | Cryo-EM structure of human NatE complex (NatA/Naa50) | | Descriptor: | ACETYL COENZYME *A, INOSITOL HEXAKISPHOSPHATE, N-alpha-acetyltransferase 10, ... | | Authors: | Deng, S, Marmorstein, R. | | Deposit date: | 2019-07-08 | | Release date: | 2020-02-19 | | Last modified: | 2020-10-14 | | Method: | ELECTRON MICROSCOPY (3.02 Å) | | Cite: | Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK.
Nat Commun, 11, 2020
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6PW9
 | | Cryo-EM structure of human NatE/HYPK complex | | Descriptor: | ACETYL COENZYME *A, Huntingtin-interacting protein K, INOSITOL HEXAKISPHOSPHATE, ... | | Authors: | Deng, S, Marmorstein, R. | | Deposit date: | 2019-07-22 | | Release date: | 2020-02-19 | | Last modified: | 2020-10-14 | | Method: | ELECTRON MICROSCOPY (4.03 Å) | | Cite: | Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK.
Nat Commun, 11, 2020
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2ER8
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7SNI
 | | Structure of G6PD-D200N tetramer bound to NADP+ and G6P | | Descriptor: | 6-O-phosphono-beta-D-glucopyranose, Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | Authors: | Wei, X, Marmorstein, R. | | Deposit date: | 2021-10-28 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.5 Å) | | Cite: | Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity.
Proc.Natl.Acad.Sci.USA, 119, 2022
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6UV5
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6UUW
 | | Structure of human ATP citrate lyase E599Q mutant in complex with Mg2+, citrate, ATP and CoA | | Descriptor: | (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | | Authors: | Wei, X, Marmorstein, R. | | Deposit date: | 2019-11-01 | | Release date: | 2019-12-25 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Molecular basis for acetyl-CoA production by ATP-citrate lyase
Nat.Struct.Mol.Biol., 27, 2020
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6UI9
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1FY7
 | | CRYSTAL STRUCTURE OF YEAST ESA1 HISTONE ACETYLTRANSFERASE DOMAIN COMPLEXED WITH COENZYME A | | Descriptor: | COENZYME A, ESA1 HISTONE ACETYLTRANSFERASE, SODIUM ION | | Authors: | Yan, Y, Barlev, N.A, Haley, R.H, Berger, S.L, Marmorstein, R. | | Deposit date: | 2000-09-28 | | Release date: | 2000-11-29 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal structure of yeast Esa1 suggests a unified mechanism for catalysis and substrate binding by histone acetyltransferases.
Mol.Cell, 6, 2000
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2ERE
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2ERG
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1QSN
 | | CRYSTAL STRUCTURE OF TETRAHYMENA GCN5 WITH BOUND COENZYME A AND HISTONE H3 PEPTIDE | | Descriptor: | COENZYME A, HISTONE H3, TGCN5 HISTONE ACETYL TRANSFERASE | | Authors: | Rojas, J.R, Trievel, R.C, Zhou, J, Mo, Y, Li, X, Berger, S.L, David Allis, C, Marmorstein, R. | | Deposit date: | 1999-06-22 | | Release date: | 1999-09-08 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structure of Tetrahymena GCN5 bound to coenzyme A and a histone H3 peptide.
Nature, 401, 1999
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1K6O
 | | Crystal Structure of a Ternary SAP-1/SRF/c-fos SRE DNA Complex | | Descriptor: | 5'-D(*CP*AP*CP*AP*GP*GP*AP*TP*GP*TP*CP*CP*AP*TP*AP*TP*TP*AP*GP*GP*AP*CP*A)-3', 5'-D(*TP*GP*TP*CP*CP*TP*AP*AP*TP*AP*TP*GP*GP*AP*CP*AP*TP*CP*CP*TP*GP*TP*G)-3', ETS-domain protein ELK-4, ... | | Authors: | Mo, Y, Ho, W, Johnston, K, Marmorstein, R. | | Deposit date: | 2001-10-16 | | Release date: | 2002-01-17 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (3.19 Å) | | Cite: | Crystal structure of a ternary SAP-1/SRF/c-fos SRE DNA complex.
J.Mol.Biol., 314, 2001
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1HU8
 | | CRYSTAL STRUCTURE OF THE MOUSE P53 CORE DNA-BINDING DOMAIN AT 2.7A RESOLUTION | | Descriptor: | CELLULAR TUMOR ANTIGEN P53, ZINC ION | | Authors: | Zhao, K, Chai, X, Johnston, K, Clements, A, Marmorstein, R. | | Deposit date: | 2001-01-04 | | Release date: | 2001-07-04 | | Last modified: | 2023-08-09 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Crystal structure of the mouse p53 core DNA-binding domain at 2.7 A resolution.
J.Biol.Chem., 276, 2001
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5JSM
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4K2J
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7LIW
 | | Local refinement of human ATP citrate lyase E599Q mutant ASH domain | | Descriptor: | (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | | Authors: | Wei, X, Marmorstein, R. | | Deposit date: | 2021-01-28 | | Release date: | 2021-05-19 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (2.85 Å) | | Cite: | Reply to: Acetyl-CoA is produced by the citrate synthase homology module of ATP-citrate lyase.
Nat.Struct.Mol.Biol., 28, 2021
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7LLA
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7KPU
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7KD7
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7STX
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7SNG
 | | structure of G6PD-WT tetramer | | Descriptor: | Glucose-6-phosphate 1-dehydrogenase | | Authors: | Wei, X, Marmorstein, R. | | Deposit date: | 2021-10-28 | | Release date: | 2022-07-13 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (2.8 Å) | | Cite: | Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity.
Proc.Natl.Acad.Sci.USA, 119, 2022
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7TOE
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5J8C
 | | Human MOF C316S, E350Q crystal structure | | Descriptor: | CHLORIDE ION, Histone acetyltransferase KAT8, SODIUM ION, ... | | Authors: | McCullough, C.E, Marmorstein, R. | | Deposit date: | 2016-04-07 | | Release date: | 2016-07-20 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.17 Å) | | Cite: | Structural and Functional Role of Acetyltransferase hMOF K274 Autoacetylation.
J.Biol.Chem., 291, 2016
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