7KD7
Crystal structure of human NatD (NAA40) bound to a bisubstrate analogue
Summary for 7KD7
| Entry DOI | 10.2210/pdb7kd7/pdb |
| Descriptor | N-alpha-acetyltransferase 40, SER-GLY-ARG-GLY-LYS, GLYCEROL, ... (8 entities in total) |
| Functional Keywords | natd, naa40, transferase, bi-substrate |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 4 |
| Total formula weight | 51051.99 |
| Authors | Deng, S.,Marmorstein, R. (deposition date: 2020-10-08, release date: 2021-06-16, Last modification date: 2023-10-18) |
| Primary citation | Deng, Y.,Deng, S.,Ho, Y.H.,Gardner, S.M.,Huang, Z.,Marmorstein, R.,Huang, R. Novel Bisubstrate Inhibitors for Protein N-Terminal Acetyltransferase D. J.Med.Chem., 64:8263-8271, 2021 Cited by PubMed: 34110812DOI: 10.1021/acs.jmedchem.1c00141 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.44 Å) |
Structure validation
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