7KD7
Crystal structure of human NatD (NAA40) bound to a bisubstrate analogue
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0010485 | molecular_function | histone H4 acetyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0043998 | molecular_function | histone H2A acetyltransferase activity |
| D | 0010485 | molecular_function | histone H4 acetyltransferase activity |
| D | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| D | 0043998 | molecular_function | histone H2A acetyltransferase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25619998, ECO:0007744|PDB:4U9W |
| Chain | Residue | Details |
| D | TYR85 | |
| A | THR174 | |
| A | SER197 | |
| A | TYR211 | |
| D | ASP127 | |
| D | TYR138 | |
| D | THR174 | |
| D | SER197 | |
| D | TYR211 | |
| A | TYR85 | |
| A | ASP127 | |
| A | TYR138 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25619998, ECO:0007744|PDB:4U9V, ECO:0007744|PDB:4U9W |
| Chain | Residue | Details |
| D | VAL140 | |
| D | ARG148 | |
| D | ASN179 | |
| A | VAL140 | |
| A | ARG148 | |
| A | ASN179 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | SITE: Essential for catalytic activity => ECO:0000269|PubMed:25619998 |
| Chain | Residue | Details |
| D | GLU139 | |
| A | GLU139 |
