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PDB: 176 件

2APV
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Crystal Structure of the G17E/A52V/S54N/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain
分子名称: MALONIC ACID, T cell receptor beta chain V
著者Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
登録日2005-08-16
公開日2006-03-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2AQ1
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Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant
分子名称: Enterotoxin type C-3, T-cell receptor beta chain V
著者Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
登録日2005-08-17
公開日2006-03-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
4K79
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Recognition of the Thomsen-Friedenreich Antigen by a Lamprey Variable Lymphocyte Receptor
分子名称: Variable lymphocyte receptor, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose
著者Luo, M, Velikovsky, C.A, Yang, X.B, Mariuzza, R.A.
登録日2013-04-16
公開日2013-06-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor.
J.Biol.Chem., 288, 2013
2APF
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Crystal Structure of the A52V/S54N/K66E variant of the murine T cell receptor V beta 8.2 domain
分子名称: MALONIC ACID, T cell receptor beta chain V
著者Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
登録日2005-08-16
公開日2006-03-21
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2APT
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Crystal Structure of the G17E/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain
分子名称: MALONIC ACID, T-cell receptor beta chain V
著者Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
登録日2005-08-16
公開日2006-03-21
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2AQ3
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Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3
分子名称: Enterotoxin type C-3, T-cell receptor beta chain V
著者Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
登録日2005-08-17
公開日2006-03-21
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2APB
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Crystal Structure of the S54N variant of murine T cell receptor Vbeta 8.2 domain
分子名称: MALONIC ACID, T-cell receptor beta chain V
著者Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
登録日2005-08-16
公開日2006-03-21
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2APX
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Crystal Structure of the G17E/A52V/S54N/K66E/Q72H/E80V/L81S/T87S/G96V variant of the murine T cell receptor V beta 8.2 domain
分子名称: MALONIC ACID, T cell receptor beta chain V
著者Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
登録日2005-08-16
公開日2006-03-21
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
2APH
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Crystal structure of human PGRP-IalphaC in complex with muramyl pentapeptide
分子名称: N-acetyl-beta-muramic acid, Peptidoglycan recognition protein I-alpha, SULFATE ION, ...
著者Guan, R, Roychowdjury, A, Boons, G, Mariuzza, R.A.
登録日2005-08-16
公開日2006-06-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of human peptidoglycan recognition protein I alpha bound to a muramyl pentapeptide from Gram-positive bacteria.
Protein Sci., 15, 2006
2AQ2
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Crystal structure of T-cell receptor V beta domain variant complexed with superantigen SEC3 mutant
分子名称: Enterotoxin type C-3, SODIUM ION, SULFATE ION, ...
著者Cho, S, Swaminathan, C.P, Yang, J, Kerzic, M.C, Guan, R, Kieke, M.C, Kranz, D.M, Mariuzza, R.A, Sundberg, E.J.
登録日2005-08-17
公開日2006-03-21
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of affinity maturation and intramolecular cooperativity in a protein-protein interaction.
Structure, 13, 2005
1BEC
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BU of 1bec by Molmil
BETA CHAIN OF A T CELL ANTIGEN RECEPTOR
分子名称: 14.3.D T CELL ANTIGEN RECEPTOR
著者Bentley, G.A, Boulot, G, Karjalainen, K, Mariuzza, R.A.
登録日1995-02-28
公開日1995-10-25
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the beta chain of a T cell antigen receptor.
Science, 267, 1995
3OWE
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BU of 3owe by Molmil
Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a High Affinity Mutant Mouse T-cell Receptor Chain
分子名称: Beta-chain, Enterotoxin SEG
著者Fernandez, M.M, Cho, S, Robinson, H, Mariuzza, R.A, Malchiodi, M.L.
登録日2010-09-17
公開日2010-11-03
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.
J.Biol.Chem., 286, 2011
1P1Z
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BU of 1p1z by Molmil
X-RAY CRYSTAL STRUCTURE OF THE LECTIN-LIKE NATURAL KILLER CELL RECEPTOR LY-49C BOUND TO ITS MHC CLASS I LIGAND H-2Kb
分子名称: Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ...
著者Dimasi, N, Natarajan, K, Rangjin, G, Dam, J, Margulies, D.H, Mariuzza, R.A.
登録日2003-04-14
公開日2003-11-11
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.26 Å)
主引用文献Variable MHC class I engagement by Ly49 natural killer cell receptors demonstrated by the crystal structure of Ly49C bound to H-2K(b).
Nat.Immunol., 4, 2003
1TVD
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BU of 1tvd by Molmil
VARIABLE DOMAIN OF T CELL RECEPTOR DELTA CHAIN
分子名称: T CELL RECEPTOR
著者Li, H.M, Lebedeva, M.I, Llera, A.S, Fields, B.A, Brenner, M.B, Mariuzza, R.A.
登録日1997-10-19
公開日1998-04-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of the Vdelta domain of a human gammadelta T-cell antigen receptor.
Nature, 391, 1998
3O6F
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BU of 3o6f by Molmil
Crystal structure of a human autoimmune TCR MS2-3C8 bound to MHC class II self-ligand MBP/HLA-DR4
分子名称: HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ...
著者Yin, Y, Li, Y, Martin, R, Mariuzza, R.A.
登録日2010-07-29
公開日2011-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of a TCR with high affinity for self-antigen reveals basis for escape from negative selection.
Embo J., 30, 2011
1JCK
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BU of 1jck by Molmil
T-CELL RECEPTOR BETA CHAIN COMPLEXED WITH SEC3 SUPERANTIGEN
分子名称: 14.3.D T CELL ANTIGEN RECEPTOR, STAPHYLOCOCCAL ENTEROTOXIN C3
著者Fields, B.A, Mariuzza, R.A.
登録日1996-10-22
公開日1997-11-12
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of a T-cell receptor beta-chain complexed with a superantigen.
Nature, 384, 1996
7RD2
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Co-crystal structure of Chaetomium glucosidase with compound 2
分子名称: (2R,3R,4R,5S)-1-{[4-({4-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-nitroanilino}methyl)phenyl]methyl}-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, ...
著者Karade, S.S, Mariuzza, R.A.
登録日2021-07-09
公開日2023-02-22
最終更新日2023-03-01
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity.
J.Med.Chem., 66, 2023
7T6W
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BU of 7t6w by Molmil
Crystal structure of Chaetomium Glucosidase I (apo)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, GLYCEROL, ...
著者Karade, S.S, Mariuzza, R.A.
登録日2021-12-14
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.
Biochemistry, 61, 2022
7T8V
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Co-crystal structure of Chaetomium glucosidase I with EB-0159
分子名称: (1S,2S,3R,4S,5S)-1-(hydroxymethyl)-5-[(6-{[2-nitro-4-(1H-1,2,3-triazol-1-yl)phenyl]amino}hexyl)amino]cyclohexane-1,2,3,4-tetrol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Karade, S.S, Mariuzza, R.A.
登録日2021-12-17
公開日2022-05-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.
Biochemistry, 61, 2022
7T66
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Co-crystal structure of Chaetomium glucosidase with compound UV-4
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, ...
著者Karade, S.S, Mariuzza, R.A.
登録日2021-12-13
公開日2022-05-04
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.
Biochemistry, 61, 2022
7T68
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Co-crystal structure of Chaetomium glucosidase with compound UV-5
分子名称: (2R,3R,4R,5S)-1-[6-(4-azido-2-nitroanilino)hexyl]-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Karade, S.S, Mariuzza, R.A.
登録日2021-12-13
公開日2022-05-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.
Biochemistry, 61, 2022
1DVF
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BU of 1dvf by Molmil
IDIOTOPIC ANTIBODY D1.3 FV FRAGMENT-ANTIIDIOTOPIC ANTIBODY E5.2 FV FRAGMENT COMPLEX
分子名称: FV D1.3, FV E5.2, ZINC ION
著者Braden, B.C, Fields, B.A, Ysern, X, Dall'Acqua, W, Goldbaum, F.A, Poljak, R.J, Mariuzza, R.A.
登録日1996-04-13
公開日1996-08-17
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of an Fv-Fv idiotope-anti-idiotope complex at 1.9 A resolution.
J.Mol.Biol., 264, 1996
2IAM
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Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
分子名称: 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ...
著者Deng, L, Langley, R.J, Mariuzza, R.A.
登録日2006-09-08
公開日2007-04-03
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
2IAN
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BU of 2ian by Molmil
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
分子名称: 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ...
著者Deng, L, Langley, R.J, Mariuzza, R.A.
登録日2006-09-08
公開日2007-04-03
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
5D2L
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BU of 5d2l by Molmil
Crystal structure of TCR C7 in complex with HCMV NLV epitope presented by HLA-A2
分子名称: ASN-LEU-VAL-PRO-MET-VAL-ALA-THR-VAL, Beta-2-microglobulin, C7 TCR alpha chain, ...
著者Gao, M, Mariuzza, R.A.
登録日2015-08-05
公開日2015-10-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.511 Å)
主引用文献Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope.
J.Biol.Chem., 290, 2015

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