7T66

Co-crystal structure of Chaetomium glucosidase with compound UV-4

This is a non-PDB format compatible entry.

Summary for 7T66

• Entry DOI: 10.2210/pdb7t66/pdb
• Descriptor: Chaetomium alpha glucosidase, GLYCEROL, N-9'-methoxynonyl-1-deoxynojirimycin, ... (7 entities in total)
• Functional Keywords: alpha glucosidase i, hydrolase, inhibitor complex, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Chaetomium thermophilum var. thermophilum DSM 1495
• Total number of polymer chains: 2
• Total formula weight: 188853.76

Authors

Karade, S.S.,Mariuzza, R.A. (deposition date: 2021-12-13, release date: 2022-05-04, Last modification date: 2023-10-18)

• Primary citation: Karade, S.S.,Kolesnikov, A.,Treston, A.M.,Mariuzza, R.A.; Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.; Biochemistry, 61:822-832, 2022; PubMed: 35476408; DOI: 10.1021/acs.biochem.2c00092

Experimental method

X-RAY DIFFRACTION (2.19 Å)