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PDB: 180 results

5D2N
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Crystal structure of C25-NLV-HLA-A2 complex
Descriptor: ASN-LEU-VAL-PRO-MET-VAL-ALA-THR-VAL, Beta-2-microglobulin, C25 alpha, ...
Authors:Mariuzza, R.A, Yang, X.
Deposit date:2015-08-05
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.099 Å)
Cite:Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope.
J.Biol.Chem., 290, 2015
1Y0M
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BU of 1y0m by Molmil
Crystal structure of of the SH3 domain of phospholipase C Gamma-1
Descriptor: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1
Authors:Mariuzza, R, Sangwoo, C.
Deposit date:2004-11-15
Release date:2006-02-21
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.2 Å)
Cite:Crystal structure of of the SH3 domain of phospholipase C Gamma-1
To be Published
1NBY
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BU of 1nby by Molmil
Crystal Structure of HyHEL-63 complexed with HEL mutant K96A
Descriptor: Lysozyme C, antibody kappa light chain, immunoglobulin gamma 1 chain
Authors:Mariuzza, R.A, Li, Y, Urrutia, M, Smith-Gill, S.J.
Deposit date:2002-12-04
Release date:2003-04-01
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen
Biochemistry, 42, 2003
1NBZ
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Crystal Structure of HyHEL-63 complexed with HEL mutant K97A
Descriptor: Lysozyme C, antibody kappa light chain, immunoglobulin gamma 1 chain
Authors:Mariuzza, R.A, Li, Y, Urrutia, M, Smith-Gill, S.J.
Deposit date:2002-12-04
Release date:2003-04-01
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigen
Biochemistry, 42, 2003
1NDG
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Crystal structure of Fab fragment of antibody HyHEL-8 complexed with its antigen lysozyme
Descriptor: ACETIC ACID, Lysozyme C, antibody kappa light chain, ...
Authors:Mariuzza, R.A, Li, Y, Li, H, Yang, F, Smith-Gill, S.J.
Deposit date:2002-12-09
Release date:2003-06-03
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray snapshots of the maturation of an antibody response to a protein antigen
Nat.Struct.Biol., 10, 2003
1NDM
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Crystal structure of Fab fragment of antibody HyHEL-26 complexed with lysozyme
Descriptor: Lysozyme C, antibody kappa light chain, immunoglobulin gamma 1 chain
Authors:Mariuzza, R.A, Li, Y, Li, H.
Deposit date:2002-12-09
Release date:2003-06-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:X-ray snapshots of the maturation of an antibody response to a protein antigen
Nat.Struct.Biol., 10, 2003
4E42
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BU of 4e42 by Molmil
Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Descriptor: CHLORIDE ION, NITRATE ION, SODIUM ION, ...
Authors:Deng, L, Langley, R.J, Wang, Q, Topalian, S.L, Mariuzza, R.A.
Deposit date:2012-03-11
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
7RM4
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BU of 7rm4 by Molmil
Neoantigen p53R175H-specific TCR 6-11 binds to p53R175H-HLA-A2
Descriptor: 6-11 T cell receptor alpha chain, 6-11 T cell receptor beta chain, Beta-2-microglobulin, ...
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-07-26
Release date:2022-02-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.33 Å)
Cite:T cell receptors employ diverse strategies to target a p53 cancer neoantigen.
J.Biol.Chem., 298, 2022
1TWQ
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Crystal structure of the C-terminal PGN-binding domain of human PGRP-Ialpha in complex with PGN analog muramyl tripeptide
Descriptor: N-acetyl-beta-muramic acid, NICKEL (II) ION, muramyl tripeptide, ...
Authors:Guan, R, Roychowdury, A, Boons, G.-A, Mariuzza, R.A.
Deposit date:2004-07-01
Release date:2004-12-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for peptidoglycan binding by peptidoglycan recognition proteins
Proc.Natl.Acad.Sci.USA, 101, 2004
2PTT
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BU of 2ptt by Molmil
Structure of NK cell receptor 2B4 (CD244) bound to its ligand CD48
Descriptor: CD48 antigen, Natural killer cell receptor 2B4, SULFATE ION
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
2PTU
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Structure of NK cell receptor 2B4 (CD244)
Descriptor: Natural killer cell receptor 2B4
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.38 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
3G39
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BU of 3g39 by Molmil
Structure of a lamprey variable lymphocyte receptor
Descriptor: Variable lymphocyte receptor VLRB.2D
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2009-02-02
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
3T0E
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BU of 3t0e by Molmil
Crystal structure of a complete ternary complex of T cell receptor, peptide-MHC and CD4
Descriptor: HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ...
Authors:Yin, Y, Mariuzza, R.A.
Deposit date:2011-07-20
Release date:2012-03-07
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (4 Å)
Cite:Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4.
Proc.Natl.Acad.Sci.USA, 109, 2012
1A2Y
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BU of 1a2y by Molmil
HEN EGG WHITE LYSOZYME, D18A MUTANT, IN COMPLEX WITH MOUSE MONOCLONAL ANTIBODY D1.3
Descriptor: IGG1-KAPPA D1.3 FV (HEAVY CHAIN), IGG1-KAPPA D1.3 FV (LIGHT CHAIN), LYSOZYME, ...
Authors:Tsuchiya, D, Mariuzza, R.A.
Deposit date:1998-01-13
Release date:1998-04-29
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:A mutational analysis of binding interactions in an antigen-antibody protein-protein complex.
Biochemistry, 37, 1998
1AC6
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BU of 1ac6 by Molmil
CRYSTAL STRUCTURE OF A VARIABLE DOMAIN MUTANT OF A T-CELL RECEPTOR ALPHA CHAIN
Descriptor: T-CELL RECEPTOR ALPHA
Authors:Li, H.-M, Mariuzza, R.A.
Deposit date:1997-02-13
Release date:1998-02-25
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Dual conformations of a T cell receptor V alpha homodimer: implications for variability in V alpha V beta domain association.
J.Mol.Biol., 269, 1997
8GON
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BU of 8gon by Molmil
SARS-CoV-2 specific private TCR RLQ7 in complex with RLQ-T1006I-HLA-A2
Descriptor: Beta-2-microglobulin, MHC class I antigen, SARS-CoV-2 specific private TCR RLQ7 alpha, ...
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2022-08-25
Release date:2023-03-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.601 Å)
Cite:Structural insights into protection against a SARS-CoV-2 spike variant by T cell receptor (TCR) diversity.
J.Biol.Chem., 299, 2023
4Z0X
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BU of 4z0x by Molmil
Structure of Hepatitis C Virus Envelope glycoprotein E2 antigenic region 434-446 bound to the broadly neutralizing antibody HC26AM
Descriptor: Antibody HC26AM heavy chain variable domain, Antibody HC26AM light chain variable domain, HCV E2 Antigen (residues 432-446)
Authors:Rangarajan, S, Shahid, S, Mariuzza, R.A.
Deposit date:2015-03-26
Release date:2016-07-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice.
Hepatology, 64, 2016
2PTV
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BU of 2ptv by Molmil
Structure of NK cell receptor ligand CD48
Descriptor: CD48 antigen
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2007-05-08
Release date:2007-11-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Structure of natural killer receptor 2B4 bound to CD48 reveals basis for heterophilic recognition in signaling lymphocyte activation molecule family.
Immunity, 27, 2007
4E41
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BU of 4e41 by Molmil
Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Descriptor: HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ...
Authors:Deng, L, Langley, R.J, Wang, Q, Topalian, S.L, Mariuzza, R.A.
Deposit date:2012-03-11
Release date:2012-08-29
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
3FF8
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BU of 3ff8 by Molmil
Structure of NK cell receptor KLRG1 bound to E-cadherin
Descriptor: CALCIUM ION, Epithelial cadherin, Killer cell lectin-like receptor subfamily G member 1
Authors:Li, Y, Mariuzza, R.A.
Deposit date:2008-12-02
Release date:2009-07-28
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition.
Immunity, 31, 2009
4PO4
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BU of 4po4 by Molmil
Crystal Structure of Lampetra planeri VLRC
Descriptor: Lampetra planeri VLRC
Authors:Gao, M.M, Mariuzza, R.
Deposit date:2014-02-24
Release date:2015-01-14
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Selection of the lamprey VLRC antigen receptor repertoire.
Proc.Natl.Acad.Sci.USA, 111, 2014
4XVJ
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BU of 4xvj by Molmil
STRUCTURE OF THE HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 ANTIGENIC 2 REGION 412-423 BOUND TO THE BROADLY NEUTRALIZING ANTIBODY HC33.1
Descriptor: HCV E2 antigen, antibody heavy chain variable domain, antibody light chain variable domain
Authors:Li, Y, Mariuzza, R.A.
Deposit date:2015-01-27
Release date:2015-03-11
Last modified:2016-12-28
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for penetration of the glycan shield of hepatitis C virus e2 glycoprotein by a broadly neutralizing human antibody.
J.Biol.Chem., 290, 2015
4ZSO
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BU of 4zso by Molmil
Crystal structure of a complex between B7-H6, a tumor cell ligand for natural cytotoxicity receptor NKp30, and an inhibitory antibody
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ...
Authors:Xu, X, Li, Y, Mariuzza, R.A.
Deposit date:2015-05-13
Release date:2016-05-18
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a complex between B7-H6, a tumor cell ligand for natural cytotoxicity receptor NKp30, and an inhibitory antibody
to be published
1G7H
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BU of 1g7h by Molmil
CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3(VLW92A)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7J
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92H)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000

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